Category Archives: L’Oreal

3D Bioprinting of Hair

Within the world of 3D bioprinting, the most exciting developments to look forward to involve the 3D printing of essential human body parts. However, for us hair loss sufferers, 3D bioprinted hair is of foremost interest.

Note that there are various 3D printing technologies with different purposes. These include: bioprinting of hair follicles that would then be transplanted; bioprinting of skin that also contains hair and sweat glands; 3D printing of scaffolds to assist in 3D culturing of hair and dermal papilla cells; and 3D printing of hair systems.

March 21, 2024

University of Oregon (US) researchers have teamed up with scientists from L’Oréal (France) to develop a multilayered artificial skin that more accurately mimics real human skin. Their research on tailored skin tissue engineering was published on March 7 in the journal Advanced Functional Materials. The artificial skin can be grown in just 18 days and relies on a novel 3D printing technique. Most importantly, these skin models have the potential to be safely transplanted into humans in future. This would paved the way for personalized skin grafts for burn victims and patients with skin diseases.

March 1, 2024

3D-Printed Skin Closes Wounds and Contains Hair Follicle Precursors

Bioprinted Skin Adipose
3D bioprinting of skin and hair via the use of adipose-derived stem cells and extra-cellular matrix. Source: Bioactive Materials, March 2024.

In a new study led by Dr. Ibrahim Ozbolat and other scientists from Penn State University (US), the researchers managed to bioprint skin as well as hair in rats in a unique way using adipose (fat) cells. The full study can be read in the latest issue of Bioactive Materials. One of the co-authors is Ryan Driskell from Washington State. I covered his work and unique skin related website in my post on skin regeneration, wound healing and hair growth.

The researchers obtained fat cells and tissue from patients undergoing surgery at a nearby hospital. They then used this tissue to correct injuries in rats via the use of a 3D printer. They also obtained adipose-derived stem cells (ADSCs) and adipose-derived extracellular matrix (adECM) from the adipose tissue to make another bioink component.

While scientists have previously 3D bioprinted thin layers of skin, the Penn team are the first to intraoperatively print a full, living system of multiple skin layers. This includes the lowest layer hypodermis, which is below the epidermis and dermis. The ADSCs and ECM also induced downgrowth of hair follicle-like structures.

According to Dr. Ozbolat:

“We are working to advance this, to mature the hair follicles with controlled density, directionality and growth. We believe this could be applied in dermatology, hair transplants, and plastic and reconstructive surgeries.”

November 16, 2023

3D Bioprinting of Hair Follicles within Skin

3D Printing of Hair in Skin.
3D Bioprinting of Hair Follicles within Skin. Source: Science Advances.

A team of scientists from Rensselaer Polytechnic Institute (US) has 3D-printed hair follicles in human skin tissue cultured in the lab. The research was published in Scientific Advances in October 2023 and led by Dr. Pankaj Karande.

December 21, 2022

New Studies on 3D Bioprinting of Hair Follicles

I am updating this post due to several new studies on 3D bioprinting of hair follicles.

  • A new December 2022 paper from China concludes that a new bead-jet enabled printing of mesenchymal stem cell laden Matrigel beads results in hair follicle regeneration. Matrigel (similar to extracellular matrix) was selected as the biomaterial for this research. Compared with conventional 3D in-situ printing techniques, bead-jet printing is specialized for stem cell therapy, with improved retention rates. The new technology might find a diverse range of uses in clinical applications for regenerative medicine.
  • A November 2022 paper from China discusses an interesting mechanical engineering approach of “in situ” bioprinting. The scientists printed bioinks directly into defective sites in order to promote tissue repair. Epidermal stem cells (Epi-SCs), skin-derived precursors (SKPs), and Matrigel were “printed” into the wounds of nude mice to promote hair follicle regeneration. The results showed successful regeneration of hair follicles and other skin appendages at 4 weeks after in situ bioprinting. Moreover, the bioprinting only slightly decreased stem cell viability. These findings support a mechanical engineering method for hair follicle regeneration.
  • A June 2022 study from Japan proposes an approach for the scalable and automated preparation of highly hair-inductive grafts using a bioprinter. Mesenchymal–epithelial interactions resulted in efficient hair follicle regeneration in mice. However, the new hair shafts remained mostly beneath the skin. The scientists then developed a unique method to enable the hair to sprout upwards through the skin. Note that the lead author of this study is Junji Fukuda, who I have covered many times on this blog.
  • A study from China that was published in September 2021 discusses a new approach in three-dimensional bioprinting for the tissue engineering of hair follicle reconstruction. This method entails a 3D bioprinting technique based on a gelatin/alginate hydrogel to construct a multilayer composite scaffold. The end results is a suitable 3D microenvironment for dermal papilla cells to induce new hair follicle formation. Update: A March 2022 summary can be read on ScienceDirect.
  • A June 2021 summary from China is a must read. It is titled “3D bioprinting for skin tissue engineering: Current status and perspectives.” It covers in detail the latest status of the main 3D bioprinting technologies (droplet-based, laser-assisted, extrusion-based and stereolithography). It then covers in detail skin bioprinting, hair bioprinting and sweat gland bioprinting. The last mentioned is not always desirable, hence the need for clinical strength antiperspirants.
  • Another far more detailed study from China that was published in May 2021 is titled: “Using bioprinting and spheroid culture to create a skin model with sweat glands and hair follicles.” The researchers managed to simultaneously induce sweat gland and hair follicle regeneration. Moreover, they discovered a symbiotic relationship between sweat gland scaffolds and hair follicle spheroids.
3D Bioprinting of Hair and Sweat Glands.
Using 3D bioprinting and spheroid culture to create skin with sweat glands and hair follicles. Source: Burns & Trauma, Volume 9, 2021.

Also make sure to read my past tissue engineering of hair follicles post covering work from Dr. Angela Christiano’s team at Columbia University. It is also summarized in the below 2019 video:

Poietis, L’Oréal, BASF and Dr. Atala

The most exciting work in this area of 3D printed hair (and skin) involves the partnership between Poietis, L’Oréal and BASF. Even after years of reading about 3D bioprinting and watching many videos on the subject, it still seems like science fiction to me. However, this is definitely not fiction, and the basic technology has already existed and been used in people for over a decade.

Dr. Anthony Atala (a pioneer who I have mentioned a few times on this blog) has two extremely popular TED Talk videos on this subject from 2010 and 2011. At the time, Dr. Atala’s work was also well covered in this article. More recently, Dr. Atala has been working with NASA to print artificial organs in space.

3D Printed Hair and Hair Systems

While we are most interested in cellular level 3D hair follicle bioprinting and transplantation, there also exist other uses of 3D printers that involve hair. Methods that make use of synthetic materials and do not entail any kind of complicated scaffolds and culturing.

MIT Media Group’s Cillia: 3D Printed Hair

The first of these was not widely covered, but since it involves researchers from MIT, I give it precedence. These scientists are part of the MIT Tangible Media Group, led by Dr. Hiroshi Ishii, and their project is called Cillia. Note that they do not discuss the human scalp whatsoever, and they are using bitmap technology to print this hair rather than any kind of actual cells.

The futurism website has a much more detailed article on the subject. Make sure to also see the work from Carnegie Mellon University for creating lifelike hair fibers using a fused deposition modeling (FDM) printer.

CRLAB (Cesare Ragazzi): 3D Printed CNC Hair System

Hair systems and prosthesis are not exactly what me have in mind when we discuss 3D printed hair. However, Italian company CRLAB (previously Cesare Ragazzi) has received tremendous publicity in recent years for its CNC 3D printed hair and scalp prosthesis systems.

You can watch a Lab Tour video of the company to learn more. Their work was even covered on in 2016. The company’s technology is essentially an attempt at making a much better wig/hairpiece/hair system/toupee than anything that is in existence today. With far less expensive and frequent maintenance requirements. Plus a superior individualized fit (scalp mapping). The technology is based on CNC systems that are being sold around the world by Cesare Ragazzi.

Grey Hair Cure Discoveries

I originally published this post in January 2016 and update it every year. Note that a grey hair cure also has implications for hair loss reversal, anti-aging treatment and regenerative medicine.

Edit: Due to the increasing length of this post, the newest grey hair cure related developments are now listed in my post on grey hair reversal.

Grey Hair Treatment

Over the past few years, I have collected quite a few interesting links related to a cure for grey hair. I kept delaying writing this post because a permanent reversal of grey hair is obviously far less important than a cure for hair loss. However, there are some interesting ideas in reversing graying hair that are also relevant to reversing hair loss. Both problems also seem to have some common pathways and genetics.

Moreover, whenever we get back a full head of hair, the vast majority of us will no doubt prefer that the new hair is pigmented. At that point, grey hair will be deemed to be a significant problem unless one prefers the salt and pepper distinguished look.

Finally, for younger people who are both balding and prematurely graying, it is a double whammy. Hair loss shampoos and vitamins and minerals do not seem to impact hair color in most people.

Why Does Hair Turn Grey?

A person’s hair color is determined by his or her pigment producing stem cells known as melanocytes working in conjunction with his/her hair follicle stem cells. Hair color depends on the presence and ratios of two types of melanins: dark eumelanins (brown and black pigments); and light pheomelanins (red and yellow pigments). Among the reasons that hair turns grey include:

  • Genetics.
  • Aging.
  • Hydrogen Peroxide Buildup.
  • Stress.
  • Smoking.

As people age, a natural buildup of hydrogen peroxide occurs in their hair follicles. This in turn causes oxidative stress, melanocyte destruction and subsequent graying. Side note: many women use hydrogen peroxide solutions to go blonde.

In 2009, a team of scientists from Germany and the UK figured out why this hydrogen peroxide buildup occurs in people as they age. They also found out why hydrogen peroxide is to blame for graying hair. Basically, in younger people an enzyme called catalase breaks down hydrogen peroxide into water and oxygen.

However, as people get older, they often have lower levels of this enzyme. They also have lower levels of other enzymes (MSR A and B) that repair hydrogen peroxide related damage to hair follicles. On Amazon, products containing catalase often have at least some favorable reviews regarding the hair darkening side effect.

The combination of high levels of hydrogen peroxide and low levels of MSR A and B disrupts the formation of tyrosinase. That enzyme is important to melanin production in hair follicles. Scientists think that something similar is at play in the skin condition called vitiligo. One interesting and unusual thing about white nonpigmented hair is that it is thicker and grows faster than pigmented dark hair.

Our bodies produce molecules called free radicals that often react adversely with other molecules. These free radicals can cause a lot of damage, but they are countered by beneficial antioxidants. However, it the balance between these two classes of molecules shifts towards free radicals, we get damaging oxidative stress. This results in premature canities, aka the earlier than expected whitening of hair.

Anti–Interleukin (IL)-17 Therapy Reverses Grey Hair

In May 2018, Italian scientists reported a complete reversal of grey hair in one 61-year old patient. He first started getting white hair around the age of 45. He was undergoing interleukin-17 therapy with secukinumab to treat scalp psoriasis. The below before and after photo after 6 months of treatment is truly astounding. The 10-month follow up showed maintenance of results.

Note that this patient also saw new hair growth. The conclusion of the scientists is especially motivating: “hair whitening and thinning caused by the aging process might be reversible”.

Grey Hair Reversal Anti–Interleukin-17.
Grey hair reversal after anti–Interleukin-17.

Minoxidil could Reverse Grey Hair

In 2017, Dr. Wilma Bergfeld told the New York Times that:

“In early testing of the anti-hair-loss drug minoxidil, she and other researchers noticed the drug sometimes also restored hair color, suggesting it was rejuvenating the melanocytes”.

In 2021, I asked Dr. Bergfeld if there was any further research on the above phenomenon. She responded that she is unaware of anything new.

It is surprising that this phenomenon is not discussed by many other physicians, since Minoxidil has been in use for decades. Make sure to read my post on how Minoxidil works to regrow hair for more on this important FDA approved hair loss drug.

On a related note, there have been several reports that glaucoma medication Latanoprost can also cause hair repigmentation.

Hair Repigmentation after Immunotherapy

Grey Hair Becomes Dark Again.
Grey hair cured and becomes dark again. Source: JAMA Dermatol.

In 2017, scientists were able to reverse grey hair in 13 of 14 patients using a new immunotherapy based cancer treatment.

The treatment entailed anti–programmed cell death 1 (anti–PD-1) and anti–programmed cell death ligand 1 (anti–PD-L1 ).

Hair Repigmentation
Hair repigmentation after cancer treatment.

The before and after pictures of two of the patients are extraordinary. I have included both in this section.

In recent years, research has found a connection between immune system involvement in both hair loss and hair premature greying of the hair.

Stem Cell Factor Protein, Krox20 and Hair Color

In 2017, scientists at UT Southwestern Center in the US led my Dr. Lu Le found that a protein called stem cell factor (SCF) was essential for hair pigmentation. Full study here. They found that the mice without SCF in Krox20 lineage cells developed grey hair early in life.

Is PC-KUS (a modified pseudocatalase) a False Flag?

In 2013, the same Germany and UK based team that was discussed earlier in this post came out with a potential way to reverse grey hair. According to the article:

The researchers found that this massive build up of hydrogen peroxide can be reversed with a UVB-activated compound called PC-KUS, a modified pseudocatalase. The research team developed this new proprietary treatment.

PC-KUS was also supposed to cure vitiligo. However, according to the UK’s NHS, the research and subsequent publicity on PC-KUS curing grey hair was a bit of a sham.

I am not sure if this avenue of work is definitely over, and perhaps these same scientists will surprise us and come out with better news in the future.

L’Oréal: A Pill to Prevent Grey Hair Forever

During the past decade, France’s cosmetics behemoth L’Oréal has led global research in the private sector when it comes to a search for a cure for grey hair. The company’s head of the “Hair Biology Group”, Mr. Bruno Bernard, is a co-inventor of a topical product to protect and/or regenerate the melanocytes of hair follicles. The patent for this product was filed in 2009.

Moreover, In 2011, L’Oreal announced that it was developing a pill that would prevent grey hair forever — as long as you continued to take the pill once a day permanently! The medicine contains an undisclosed fruit extract that mimics the chemical tyrosinase-related protein (TRP-2), an enzyme that protects pigment production.

Unfortunately, this pill will not cause existing grey hairs to darken, but instead, just prevent new grey hairs from forming. The pill was supposed to become available in 2015, but now we are now well past that year.

Dr. Mayumi Ito, Wnt Signaling and Hair Pigmentation

Dr. Mayumi Ito is a renowned Japanese hair loss research scientist who got her Ph.D from Nagoya University in 2003. She now does research and teaching at New York University. She has co-authored numerous papers on the impact of Wnt signaling on hair follicle growth and regeneration. On this blog you can find many posts that discuss this important subject matter.

In 2011, Dr. Ito found that Wnt signaling also explains hair losing its pigmentation. Her team even restored hair color in mice in 2011 via manipulating the Wnt pathway. It remains to be seen when they will experiment in humans (via stem cell injection or gene therapy) and see a successful reversal of grey hair.

Also in April 2016, scientists (led by Dr. Ito) at NYU Langone Medical Center in New York found the molecular pathways responsible for creating the color of skin and hair. They found that a signaling pathway known as Edn/EdnrB interacts with other pathways (in particular, the Wnt signaling pathway).

This in turn causes the proliferation of melanocyte stem cells (McSCs) that are involved in the earliest stages of skin and hair pigmentation. This suggests that targeting Edn/EdnrB signaling in McSCs can be a therapeutic approach to promote hair pigmentation retention.

Is Dr. Cotsarelis also Working on Hair Pigmentation?

Interestingly, in December 2011, the renowned Dr. George Cotsarelis and Dr. Mayumi Ito co-filed for a patent titled: “Methods for generating new hair follicles, treating baldness, and hair removal.” This patent was approved in December 2015.

In the description to the patent, it ends with “The present invention also provides methods for hair removal and inducing hair pigmentation.” Quite incredible. A three-in-one solution (hair regrowth, body hair removal, and grey hair reversal). If only Dr. Cotsarelis’ predictions and optimism would be realized faster than he thinks or claims.

Can Finasteride Make Grey Hair Darker?

Over the years, I have read quite a few testimonials on hair loss forums where Finasteride users have claimed that their hair darkened while on Finasteride (which reduces DHT levels). The majority of these patients had very limited quantities of grey hair to begin with, so it was hard for me to tell from their before and after photos (when available) if this phenomenon was true or not. Also see my post on natural DHT blockers.

However, in 2014, forum member “bverotti” who is a hair transplant clinic representative in Belgium posted a stunning now deleted before and after image of one of the clinic’s patients on Finasteride. While it shows blonde hair turning brown, I think of that as the same as grey hair turning brown or black. Also, see this hair darkening on finasteride post on Reddit.

I think that DHT, besides making many people go bald, also makes some of them go grey much sooner. I do not know if this has ever been shown to be true in any kind of study, and I could be wrong in my observation.

Using similar logic as in the above paragraph regarding Finasteride, I think that the much stronger Dutasteride can also reverse grey hair. Moreover, a few of the commentators in my post on Dutasteride Testimonials mention that the drug darkened their hair.

Could Platelet-Rich Plasma (PRP) Darken Hair?

I have covered PRP to treat hair loss many times on this blog. While the results are never guaranteed and PRP will not bring back hair in totally bald areas of the scalp, there are now numerous doctors who believe in the product. I am skeptical, but willing to listen to them.

More relevant to this blog post’s subject matter, in November 2015, Dr. Carlos Wesley started an interesting thread on the BTT forums with a photo showing PRP and ACell mesotherapy darkening some previously transparent scalp hair. This was very surprising to me. Moreover, he states that “An additional finding that has also been observed by other practices throughout the world is that PRP can help return some of the original hair color to follicles.” It seems like PRP could be stimulating melanocytes in hair follicles.

Update: A number of other doctors have confirmed this phenomenon of PRP darkening hair color in rare instances.

Grey Hair Reversal PRP

Stem Cell Transplants to Cure Grey Hair

I have discussed Dr. Takashi Tsuji on this blog numerous times in the past. Several of his old videos have shown black pigmented hair growing on a mouse after stem cell transplantation. Moreover, this article on his work has the following sentence in it: “He combined a number of stem cells to adjust the density and color of the hair, raising the possibility of a cure to graying strands.

Will Telomerase Activation Therapy Reverse Grey Hair?

There are a number of online testimonials regarding telomarase therapy via the ingestion of the TA-65 supplement reversing grey hair and/or growing new hair. There are also many opinions to the contrary. I cover all this and more in my post titled “TA-65. telomerase activation and hair regrowth“. Other anti-aging compounds such as Rapamycin are also being tested for hair pigmentation.

Cancer Treatments that lead to Hair Repigmentation

There have been various reports of people reversing their grey hair while being on drugs to treat cancer. For example:

Natural Remedies and Vitamin Supplements

Natural treatments and remedies for hair loss can sometimes also benefit hair color and pigmentation modestly. However, popular vitamin supplements such as melatonin, B-12, biotin, iron, calcium, zinc, copper, manganese, vitamin D, cysteine and selenium will not change hair color significantly in most people. If a person is severely deficient in any of these important vitamins and minerals, natural remedies can reverse grey hair on rare occasions.

Fo-Ti Root

Several studies as sell as numerous online anecdotal success story reports suggest that Fo-Ti root can darken grey hair. Fo-Ti is also knows as Fallopia multiflora, He Shou Wu and Polygonum multiflorum. Dr. Jerry Cooley told me that some of his patients have seen grey hair reduction when on a shake product containing Fo-Ti.

Make sure to read reviews and search for user experiences in relation to hair color changes before purchasing Fo-Ti root. Also of note, a new popular supplement pill product called Not Today Grey contains Fo-Ti Root as a key ingredient. Please note that excessive consumption of Fo-Ti root can damage your liver.


Calcium Alpha-Ketoglutarate (Ca-AKG) is though to have anti-aging properties. At least in aged mice. Some reviewers of an AKG acid supplement on Amazon (scroll down) mention that their hair darkened while on the product. Dr. Arvind Poswal of India told me that his Ca-AKG product has darkened hair color in multiple people. Also note this study that found α-ketoglutarate (α-KG) stimulated quiescent (telogen) hair follicles to anagen phase hair growth.


Some patients have iodine deficiency, often due to underactive thyroid gland or hormone disorders. Supplementing with iodine can darken grey hair or prevent further graying.

B Vitamins

Vitamin B12, Biotin and other B-complex supplements can help with your hair color in rare instances. However, make sure to get tested first to make sure that you are really deficient in B-12, folate or other B vitamins.

N-Acetyl Cysteine

N-Acetyl Cysteine (NAC) is sometimes touted on sites such as Reddit as benefitting hair color. Not much evidence on this, but its key benefit is proclaimed to come via an increase in glutathione levels.

Iron Deficiency

One of the most common reasons for premature hair loss is iron deficiency. This is especially true for pregnant women, vegans and people on extreme diets. In rare instances, a lack of iron can cause premature grey hair.

Mucuna Puriens

A 1989 report found that treating an 85-year old woman with Mucuna pruriens extract powder for her Parkinson’s disease resulted in drastic darkening of white hair.

Fluoxetine (SSRI)

Antidepressants such as Selective Serotonin Reuptake Inhibitors (SSRIs) have been known to cause hair loss. However, in 2017, a report from Germany discussed how Fluoxetine promoted hair follicle pigmentation. However, the work was done in dissected sample hair from two females and not on actual scalps. Another study from 2020 suggested that Fluoxetine promotes human hair follicle pigmentation via serotonin reuptake inhibition. This could be a new antigreying treatment strategy.

Grey Hair Cure Scams

While not as proliferate as in the hair loss cure industry, the grey hair reversal market is still full of scams. Moreover, while some products have been FDA approved and proven to reverse hair loss in numerous patients, nothing of that sort can be said for products that are touted to reverse grey hair to pigmented hair. Most of these products are natural supplements that will do nothing for your hair color.

In 2015, the US government went after various companies that were making fraudulent claims about their products being able to treat grey hair successfully. Prior to that, in 2013, a nutritional supplement company called “Rise-N-Shine” promised a pill that would permanent cure grey hair. Wonder if that pill ever came into stores, and if so, how many gullible people purchased it?

Proctor & Gamble’s ME+ Molecule Hair Dye

Until a cure for gray hair does come out, people will have to accept their graying locks, or continue to use hair dyes. In 2013, Proctor & Gamble came out with a supposed permanent hair dye based on a new proprietary ME+ molecule. The new molecule (chemical name 2-Methoxymethyl-p-Phenylenediamine) was apparently a result of 20 years of research.

Proctor & Gamble’s website also raved about ME+ in early 2014, but it does not seem like all this early optimism has led to any kind of new blockbuster permanent dye product.

Stress and Plucking will not Cause Grey Hair

Most of the articles I have read on this subject seem to indicate that for the vast majority of people, stress will not cause early premature graying of hair. Plucking hair will definitely not cause it to go grey. Both of these myths are old wives’ tales.

Some articles suggest that US presidents have grayed a lot while in office. However, in my opinion, these presidents’ parents were also usually fully grey haired in their old age. So it is not surprising to see more white hairs appearing on presidents’ heads when they are in office in their 50s and 60s. In all likelihood, it is grey hair genes rather than stress that causes middle-age greying.

Update: A new 2021 study found that grey hair could possibly be reversed by relaxation and taking vacations. Small sample size, limited results, and only in those below age 40.

A 2020 study found that hair turned grey and white more rapidly in mice when exposed to major stress. The effects were via the sympathetic nervous system (fight or flight response).

Grey Hair is not Always a Sign of Ageing

Since grey hair usually only affects people in their mid-30s and aftermath (and a full head of white hair is almost never seen in those below the age of 50), most people assume that it is a sign of ageing. However, this is not always the case. There is no shortage of celebrities on TV that have grayed at a very early age.

Perhaps the two most famous examples here in the US are Anderson Cooper and Jay Leno, who both look very young for their age in that video despite graying in their 20s. Cooper started to go grey at just 20 and Leno at 29 according to his statement in that video. Neither of them seem to have any health issues despite now having been grey for decades. If anything, both seem to be aging at slower pace then the average human.

Hair Color in Men versus in Women

Grey hair is a far greater concern for women than for men. For the former, it represents a sign of aging and an almost certain end to careers in acting and modeling unless the hair is dyed all the time. The women’s hair dye market is worth billion of dollars per year.

For men, this is not true, and some are even purposely buying grey hair dye in order to look like George Clooney. The salt and pepper look often makes men seem distinguished. However, some famous men such as Mr. Giuliani prefer to darken their hair even in old age.

Other News and Research on Grey Hair Reversal

Update: A September 2019 case report from India found premature hair graying reversal after the use of Melitane 5% lotion and oral hair supplements. Melitane ™ from Redenhair is a biomimetic peptide agonist of an important melanocyte-stimulating hormone.

Update: In May 2018, researchers from the NIH and the University of Alabama discovered a connection between hair color and immune system activity. Lead researcher Dr. Melissa Harris runs a lab that researches melanocyte stem cells.

Update: In August 2017, a study concluded that forced epilation in mice resulted in melanocyte cell and hair color regeneration. i.e., a potential grey hair cure in humans.

Update: In June 2017, a very unique experiment on one South Korean patient showed significant hair darkening. This success was achieved after treatment with a 1,927-nm fractionated Thulium laser and Polydeoxyribonucleotide injections.

Update: In March 2016, researchers in the UK discovered key genes for grey hair and more. The IRF4 gene’s presence seems to correlate with an earlier loss of hair color.