Han Bio Hair Multiplication via Dermal Papilla Cells

At the end of March, I read about a new South Korean company named Han Bio. Apparently, this company has managed to successfully develop a dermal papilla cell culturing technology.

Update: October 2021 — Clinical trials will start in the first half of 2022. Han Bio will partner with Dt&CRO. The latter is South Korea’s first and only full-service contract research organization (CRO). Non-clinical trials will commence in November 2021.

Update: Another article from March 2021, with CEO David Kang making a bold prediction:

“By collecting 50 to 100 healthy hair follicle tissues from the back of a patient suffering from hair loss, extracting the dermal papilla cells, cultivating them, and transplanting them back to the head, we can fundamentally cure hair loss.”

Of course at first I was incredulous. However, after further research, I decided that I should at least take the company semi-seriously. Han Bio’s blog is especially extensive. Some hair related articles on there go into many pages, so be sure to navigate thoroughly (after translation). Another version here seems to have additional news.

Note that when I contacted the company, they directed me to the above blog.

South Korea: Groundbreaking Hair Loss Treatments

South Korea is a world leader when it comes to plastic surgery and cosmetic procedures. When it comes to treating hair loss, South Korea is especially impressive in developing and/or using new technologies. For example:

  • South Korea is one of only two countries in the world where Dutasteride has been approved for treating hair loss.
  • The work of Dr. Kang-Yell Choi and CK Biotech in developing PTD-DBM to target CXXC5.
  • PGD2 inhibition technology via Stemore.
  • DKK-1 research and patent for locally-based Bioneer.
  • My favorite: Allogeneic Person-to-Person Hair Transplants.
  • South Korean companies are also at the forefront of developing stem cell related products, including AAPE and ADSC. Most such currently available products likely have limited to no benefits towards hair growth.
  • Finasteride injections.
  • Moogene.
  • Update: May 2021 — Epibiotech.
  • A disproportionate amount of research when it comes to hair growth from natural products. Especially from sea vegetables and algae.

Han Bio’s Dermal Papilla Cell Storage and Culturing

Note that Han Bio is also called Hanmo Bio and Hanbio Group in news articles and on the company’s site. The externally located blog has some lengthy posts regarding this new technology. Some include images and video (screenshots further below).

In December 2020, Han Bio introduced its dermal papilla cell storage service called HDPC-480. The list price is 4.8 million South Korean Won ($4280 at current exchange rates). They offer a steep discount for the first 500 patients.

Note that in the western world, we have a similar option available via HairClone (UK). Moreover, HairClone has already been active for several years.

Han Bio Dermal Papilla Cell Storage
Dermal Papilla Cell Storage. HDPC-480 procedure from Han Bio.

According to the balding CEO Kang Da-Witt (also called Kang David):

“Han Bio has secured technologies to separate and regroup the dermal papilla cells in hair follicles. It would take just a single strand of a patient’s hair to cultivate enough cells to reproduce around 30,000 hair strands.”

The company’s method is described as “chopping separation technology” after translation from Korean into English.

Han Bio has finished construction of its first plant, where the company stores and cultivates patient dermal papilla cells. These can then be cultured, multiplied and then implanted into the same patient via a hair transplant. This new plant will open by the end of May 2021.

Han Bio Clinical Trials and Patents

Han Bio Presentation
Han Bio video presentation screenshot.

Han Bio will start clinical trials in the second half of 2021. According to CEO Kang Da-Witt, he expects that the time required for clinical trials will be shortened. This is due to a favorable new South Korean law which became effective on August 28, 2020. It is designed to help fast-track the market entry of regenerative medicine and biologics related products. Similar to Japan’s fast-track laws.

Han Bio is now preparing to apply for patents in the US, Japan and China. The are also open to out-licensing the technology.

Transplanting Someone Else’s Dermal Papilla Cells

From Han Bio’s extensive blog, one FAQ section caught my eye. It seems like the parent company of “Hanmo Bio” has successfully transplanted hair stem cells from one person to another. Without any immune reactions.

Dermal Papilla Transplant
Dermal Papilla Cell Transplant from Another Person.

Obviously, this all sounds way too good to be true. But I have to prognosticate.

Asian countries dominate the world in the manufacturing of nano-scale semiconductors, microchips and integrated circuits. Perhaps our invisible-to-the-eye dermal papilla cells are next?

32 thoughts on “Han Bio Hair Multiplication via Dermal Papilla Cells”

    1. I did, but they just referred me to their blog. They did answer my timeline question and said good chance trials can be completed before 2025 due to the new favorable regulations.

  1. Hi Admin,

    Any update from Hairclone? Are they still in position to offer cell injection this year to clinics?

  2. Great thanks for the find, but are they working on hair cloning?and im not fond of ukhairclone they have nothing going on other than freezing your follicles !

  3. “By collecting 50 to 100 healthy hair follicle tissues from the back of a patient suffering from hair loss, extracting the dermal papilla cells, cultivating them, and transplanting them back to the head, we can fundamentally cure hair loss.” Wait I’m confused so they take the dermal papilla cells from the follicles they then create hair follicles from that and then transplant to the person’s scalp? Or is this another replicel?

  4. I have more hope for this company than Hairclone lol. Hairclone with their freezing hair follicles business lol. I dont want to say anything more.

  5. Hello Admin,

    I wanted to get your perspective on this: Do you believe the pandemic will drastically delay the availability of any possibly future cure for hair loss? I appreciate your opinion. Thanks!

  6. @ADMIN @HLC2020 @hairlosscure2020

    what is the movement at HopeMedicine?
    When will they publish their website?
    When will they Start trials For HMI-115?

  7. Don’t see the hype, they’re doing the same thing hairclone are doing now and Aderans have done in the past, DP cell multiplication. We’ve already seen the results and they don’t grow new hair, just thicken existing.

    Changing the way you administer it isn’t going to make any significant changes in outcome IMO.

    1. Hey Sahak…Check out this patent…WO1994005250A1..it’s an old 1994 which means it can be used by any one now…and it showed 100 % success rate…
      I am in the process of buying the compounds and mixing it my self…
      All the compounds are organic and they are sulfur based .

        1. I will report here…and hopefully will provide before after photos …
          I think this patent is legit…and would be nice if other people give it. A try …
          Have you read the claim and patent details ?

  8. They talk as if they were already successful don’t they?
    I don’t understand if this is another pretentious claim or they actually got something.
    Anyway the idea that a company we’ve never heard before could come out of the blue and cure hair loss is fun

  9. If half of what they say is true, they would have been acquired by now. they would have been billions eur worth. come on guys, almost a year ago a “start-up” biontech was discovered by pfizer and now they are playing for cancer treatments.
    i would only believe if loreal or big pharma acquires them or make partnership with them

  10. Reminds me of “Stemore” – appeared out of nowhere with groundbreaking treatments.

    Then quiet for a long time and now with a much more conservative timeline and no public statements at all.

    Han Bio‘s CEO looks like a character from “The Office”. Which makes him almost more credible than one of these over-the-top-styled model-like CEOs.

    Great find, Admin. The more players the better!

  11. Nice birthday present for me today.
    Well if the CEO is balding we can focus on his head as proof of concept.

  12. Why would they need to transplant hair from one person to another if all you need is 50-100 hair follicles? I mean even Norwood 7 people can manage to find 50-100 hairs don’t you think?

  13. Well, this may be similar to hairclone. But do you know the difference? In the western world something that will take 15 to 20 years to complete and get approved can be fast tracked in South Korea. And it’s proven South Korea has massive success, not necessarily with hair loss cures, but with things in a similar arena. This is definitely worth watching. Heck, I’m in the US and I’d fly to SK to get this done if I had to, though I don’t think I’d have to.

    I think other cures (pharm) will “help” with hair loss but the only true cure is hair cloning. If they can clone them you can literally keep getting hair transplants until you’re happy with your thickness – if you’ve got the money, that is (meaning if you’re quite bald it’s going to be costly to clone and get then MANY transplants as it’s usually just 3-4K per procedures, typically).

  14. I have a deja vu. Maybe they should consult replicel to learn where this will end. Even though I’d welcome a cure through cell injection over one with the manual transplant of cloned follicles, like tsuji wanted.

  15. Admin, anyword on how the funding for 4.8 million for Dr tsuji to be able to start human trials is going? Either way i think most people who have researched this topic can relise that its not going to happen until the next decade mark my words.its just not feasable !

  16. If true, this would be a dream come true. I’m not getting my hopes up though. I blindly put all of my faith into Replicel and followed them closely for YEARS, only to be punched in the stomach.

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