Category Archives: Hair Loss News

Hair Loss News, Kerastem, SM04554

This Month’s Hair Loss News

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Hair loss news first:

— I have covered Samumed and its SM04554 product a few times on this blog in the recent past. The drug is likely not going to be a miracle hair loss cure. I was therefore impressed that the company’s CEO Osman Kibar still managed to recently get profiled on a Forbes magazine cover page. In any case, a few days ago Samumed completed its Phase 2 clinical trials. Now we can only hope that they choose to continue with Phase 3 trials.

— Seems like South Korea’s Dong-A ST updated the Phase 1 clinical trials page for its DA-4001 topical finasteride product.

— Sweden based Follicum’s US patent was approved in July. The patent covers the drug candidate FOL-005.

— HairCell, yet another new startup in the hair loss world. This one wants to use a “bioelectric stimulator combined with a micro infusion pump”. Even if the vast majority of these new entrants end up as outright failures or frauds, the frenetic new activity in the hair loss world is great. HairCell’s phase 1 clinical trials have not yet commenced.

— HLT forum member “jgray201” has a very interesting thread that he started in 2012, but updates every so often including several weeks ago.

— Commentator Peter Renardo gives us some more updates on his decades old artery ligation procedure. Extremely interesting, although I would never go through with such a procedure just to save my hair.

— A 2015 presentation on Kerastem by Dr. David Perez-Meza from Spain was posted on an Italian hair loss site last month. Results in 6 patients showed an improvement in all, with an average 14 percent increase in hair count at 6 months. Not that great for the price people pay for this treatment unless the results last for years.

— A huge increase in men wanting to become women (MTF transsexuals) in the UK. This will lead to many interesting before and after MTF transition photos of scalp hair regrowth via medication, transplants and castration. The increase in women wanting to become men (FTM transsexuals) is not so useful for our purposes.

— El Chapo going bald, although the link between stress and permanent hair loss is tenuous at best in my opinion.

And now on to medical items of interest:

— Stem cell stimulating regenerative dental fillings could eliminate the need for root canals.

— Artificial pancreas next year?

— Extremely interesting article on “pausing” people so as to then bring them back from the dead.

— Growing human bones from fat cells.

— Finally, we have a biodegradable absorbable stent for heart patients with blocked arteries.

— 3-parent DNA containing life-forms seem healthy when it comes to monkeys. Note that the UK has already approved this technology for human embryos.

— 3D printed jaw for cancer survivor.

— Wired magazine’s Kevin Kelly: Next 30 years in technology.

— Thanks to commentator “Susana” from Portugal (who is usually quite pessimistic) for providing us with this link on groundbreaking skin replacement technology from Spain.

Claire Higgins, Hair Loss News, Kythera Biopharmaceuticals

Hair Loss News Items of Interest

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Hair loss news first:

— I just found out that Devon Grimmé from Follicept unexpectedly passed away today at the very young age of 27. He made many helpful comments over the past year while testing Follicept’s product on himself. Also see my post from earlier this year regarding Follicept.

— Kythera submitted an Investigational New Drug Application (IND) to the US FDA for KYTH-105 (Setipiprant).

— The renowned Dr. Claire Higgins recently made a great presentation on re-engineering the human body. I found her team’s experiment and findings on hair growing dermis transplanted under non-hair growing epidermis growing hair through the previously barren epidermis very interesting. In contrast, the hair growing epidermis transplanted over non-hair growing dermis ceased growing hair.

It makes obvious sense of course since the critical dermal papilla cells are in the dermis that lies below the epidermis. The most interesting part of the below video, however, is at 33:47 during the question and answer segment where she mentions how people are now using “rollers with spikes on them” to stimulate dermal papilla cells.

I have mentioned dermarolling and microneedling based intentional wounding on this blog before. It is great to see that even Dr. Higgins thinks there is some legitimacy to this crude concept. Unfortunately, the wounding has to be done at a very precise level, manner, frequency and duration. So most  hair loss forum members who are doing this are unlikely to be doing it correctly. I can fathom a day in the near future when we will go to clinics to get professionals to do this for us. i.e., we will pay to have someone injure our scalps and bleed us, all in the name of more hair.

— On rare occasions, I promote someone or some idea on this blog that I do not fully understand or even trust. The only reason I do this is because my intuition tells me that there is some serious potential behind this person or idea even if some of the subject matter goes above me. If a person is extremely passionate about his idea, is also very intelligent (especially when it comes to hair, chemistry and biology) and is well spoken, I get an urge to post about him or her.

Getting back to the subject matter, this new Swisstemples hair loss treatment blog is extremely interesting and the author has also e-mailed me a few times. He does not sell anything directly as far as I can tell. I would probably not buy anything from sites that he starts to recommend, since some of these products may not be 100 percent safe or thoroughly tested. I am more cautious than most when it comes to taking drugs, especially oral drugs.

A lot of guys are participating in “group buys” of products from strangers in China and Eastern Europe. Absolutely foolish in my opinion, but perhaps the fools will have full heads of hair while I continue losing ground on Finasteride. I only posted this link for the entertainment and educational value. I will not participate in these group buys.

–Very surprising that the BBC had such a speculative article: can a bang on the head lead to hair loss?

— Spironolactone is a potentially miraculous product for some, and also very cheap. Besides helping with hair loss, it can even reduce persistent high blood pressure.

— I mentioned Arfy and Ernie Primeau in a post from 2013, and just like the latter, the former is back again with a vengeance. The hair loss world is quite something. Why on earth would one want to go watch a movie on a weekend night when one can find far better plots on hair loss forums?

— An interesting new video on balding.

And now on to medical items of interest:

— Amazing videos on bioengineered organs.

— At first they were blaming the Chinese for moving too fast, but now they want to do it themselves. Western scientists seek permission to genetically modify embryos.

— George Church is a brilliant scientists and he is all for genetic engineering.

— Spanish cancer patient receives 3D printed ribs from an Australian company in a world first surgery.

— Getting closer to an invisibility cloak. Perhaps a future hair loss treatment may involve visuals…i.e., we will have others (and the mirror and the camera) see us as we want them to?

— DARPA brain interfaces coming.