Category Archives: Kerastem

Kerastem, Wounding and Other Hair News

Kerastem Update

Kerastem STYLE phase II clinical trial results update. Somewhat positive news of 17 percent increase in hair count at 6 months post-treatment. However, they only treated men in the early stages of hair loss (Norwood Scale I to III).

Wounding and Hair Growth

New hair from wounding.
Single hair follicle regeneration after wounding in elderly man.

Reader “omg” posted an interesting link to a study from Taiwan with a great title: “Never too old to regenerate (hair)”. The researchers report on an 80 year old man who regrew 1 brand new pigmented black hair after scalp wounding due to excision of a basal cell carcinoma.

Yet more evidence in support of wounding, the main idea behind the work of well known company Follica. The new (or regenerated old) hair remained black at the 42-month time of follow-up. I do not think the claim that the researchers make that this is the world’s first case of wounding led hair growth in human skin is true.

Other Hair News this Month

— A potential improvement in current hair regeneration technology from Japan via self-sorted hair follicle germs (ssHFGs). I visualize an image of ant collaboration (which creeps me out a bit), each time I read that term. Dr. Junji Fukuda who I have covered on this blog before is a lead author. Update: A new article on this development came out on February 1, 2018.

— Dr. Takashi Tsuji was back in the news a couple of weeks ago. He is leading a Japanese team that includes RIKEN researchers that will develop technology to analyze human health ramifications of changes in people’s hair shape and quality. According to Dr. Tsuji, some research indicates that certain changes in human hair components are unique to people with diseases such as cancer and diabetes. Perhaps in future one can detect cancer earlier depending on hair analysis.

— Discussion about Donald Trumps’s hair never seems to get old when it comes to the major newspapers. I previously discussed Mr. Trump’s usage of Finasteride as well as a 10 page detailed article on his hair. Now come news that his daughter Ivanka has claimed that Donald Trump has had scalp reduction surgery.

Hair transplants could cure migraines in some per Turkish surgeon Dr. Safvet Ors. Actual study was published a few months ago despite major newspapers only covering the development more recently.

Topical Tofacitinib 2% ointment at least moderately effective in 3 of 10 patients suffering from alopecia areata. Dr. Brett King led the study. Hopefully, Aclaris will see better results for male pattern hair loss sufferers with their topical JAK product when it finally comes out. Fingers crossed.

Kerastem CEO Update

A few hours ago Kerastem’s CEO Mr. Brad Conlan sent me an e-mail for the first time ever. The timing of this e-mail is quite appropriate considering that I just mentioned Kerastem in my recent post related to yet another new study finding some positive correlation between adipose tissue (fat cells) and hair growth. Note that in that post, the study that I discussed entailed Kerastem’s technology (even though the UK newspaper articles that covered the development did not state so anywhere explicitly).

I am pasting Mr. Conlan’s e-mail verbatim below in blue font. Please keep discussions in the comments here civil and related to this subject matter. Unrelated comments should continue to go in my last (“brief items of interest”) post. From the first link in the below pasted e-mail, I liked the following quote from lead investigator Dr. David Perez-Meza, although it is worth keeping in mind that the study had a very small sample size of 6 patients:

“We are very pleased with the clinical outcomes of our hair regeneration study, as they represent this procedure is safe and that results are on par or better than those of traditional medical approaches to hair loss”.


Dear Editor,

I wanted to pass along that the Kerastem UK clinical study results were recently published in the Journal of Stem Cells and Cloning.

http://www.prweb.com/releases/2017/07/prweb14496474.htm

We were highly encouraged by the results of the UK study and proceeded to a 70 patient, US IDE clinical trial focused on Androgenetic Alopecia. US Clinical Trial details can be found below:

https://www.clinicaltrials.gov/ct2/show/NCT02503852?term=STYLE&rank=1

We expect to present the results from the US clinical in the Fall of 2017.

Kind Regards,

Brad Conlan
CEO
Kerastem