List of Exosome Suppliers for Hair Loss

List of Exosome suppliers to the hair growth market mentioned in this post:

1) Direct Biologics (US). Bone marrow derived.

2) Elevai (US). Wharton’s Jelly derived.

3) Kimera (US). Placental derived.

4) ExoCoBio (South Korea). Adipose stem cell derived from rose petals.

5) Exomide (South Korea). Adipose stem cell derived.

6) Vitti Labs (US). Placental derived.

7) New Life Medical Services (US).  Dermal papilla cell derived.

8) Revive Exosomes (Thailand). Umbilical cord derived.

9) Dermoaroma (Italy). Derived from bovine colostrum (first milk).

When I wrote my first post on exosomes for hair growth in 2019 and an update in 2020, there were few companies that supplied the product in the US. And just one company was dominating sales to the hair loss market. However, it seems like doctors outside the US are nowadays using a much wider range of exosome products and suppliers. Hence the reason for this new post.

Note that the US FDA released a consumer alert in 2020 in relation to regenerative medicine products such as stem cells and exosomes. Thereafter, a number of hair transplant surgeons and dermatologists in the US stopped offering exosomes as a hair loss treatment. However, usage outside the US is far less regulated.

According to one well known US hair transplant surgeon who e-mailed me last year:

“The regulations is a real quagmire. Exosomes cannot be used with any claim of growing hair. You can’t market it. Some companies say that it is ok to use off-label as long as you don’t make claims. Others say you are at risk.”

“The debate over the use of placental or bone marrow still exists and I personally believe placental will be better.”

Bone Marrow versus Umbilical Cord

A number of key factors differentiate exosome products:

  1. Concentration in particles/mL. The typical range seems to be 0.5-2.5 billion p/ml, but much higher numbers are available and preferred (to some extent). For example, Direct Biologics says that every mL of its potent XoFlo product delivers over 10 billion extracellular vesicles (EVs). Vitti Labs EV-PURE product contains 15 billion extracellular vesicles per mL.
  2. Size in nm. The typical range is 30-200 nm.
  3. How the exosomes are derived. The two most common sources are bone marrow and perinatal (umbilical cord/Wharton’s jelly, placental and amniotic fluid).

In the case of bone marrow, the extracellular vesicles need to be derived from the marrow of a young adult who is in great health, has no diseases and hopefully led a healthy lifestyle. However, adult-derived stem cells will never be as good as what Dr. John Cole calls “T-0” stem cells (see video further below).

Also of note are differences in delivery mechanisms (often governed by national regulations). Injections, microneedling and even just plain topical application all seem to be popular.

Also relevant are the specific cells used to derive the exosomes from. A September 2023 literature review analyzed 16 studies on exosome treatment for hair restoration. The extracellular vesicles were isolated from either adipose-derived stem cells (ADSCs) or dermal papilla cells (DPCs). The results were deemed to be favorable. In fact, even topical ADSC exosomes demonstrated significant increases in hair density and thickness in 39 AGA patients. No significant adverse reactions and side effects were reported across the 16 studies.

List of Exosome Suppliers for Treating Hair Loss

The below list of companies have become well known for making exosomes specifically for the hair growth market.

Direct Biologics

Direct Biologics ExoFlo
Direct Biologics ExoFlo Exosomes.

The most popular exosome producing company in the US (when it comes to the hair growth market) is Direct Biologics. When I wrote my post in 2019, all of the main hair transplant surgeons seemed to be using their ExoFlo™ product (also marketed as XoFlo™). Among these included Dr. Jerry Cooley, Dr. Daniel McGrath and Dr. John Cole. However, the Direct Biologics product is drived from bone marrow mesenchymal stromal/stem cells (BM-MSCs). So is not a “T-0” product.


Elevai Exosomes
Elevai Exosomes for Hair Loss.

Based on two recent favorable reviews, I am curently most excited about Elevai (US). Just under half-way into the below recent October 2023 video, Dr. John Cole implies that he is currently a fan of Elevai exosomes and the company’s CEO. These extracellular vesicles are mesenchymal-derived stem cells from Wharton’s Jelly (i.e., the umbilical cord). So it is a “T-0” exosome.

Moreover, in a recent interaction on Instagram with Dr. Sahil Mrigpuri (India), he told me that he is seeing good results with exosomes sold by DermapenWorld (Australia). On the company’s website, they say the following:

“DermapenWorld has sourced ethically produced Exosomes. These are multipotent, highly versatile, the youngest and purest source. You can think of these as the cream of the crop.”

However, upon further research, I found out that Dermapenworld is in fact buying these from Elevai Labs. Note that Dermapenworld is the manufacturer of the world’s leading microneedling pen.


Kimera XoGlo
Kimera XoGlo Exosomes.

Also well known in the US is Kimera. According to an interesting article on their site, the company’s exosome products:

“Include sterile suspensions of isolated MSC exosomes derived from isolated, perinatal, mesenchymal stem cells.”

On one of the pdfs on the company’s website, they claim that their XoGlo® exosomes:

  • Increase the number of hair follicles in the growth phase.
  • Regenerate dermal papilla cells of the hair follicles.

The company’s placental-derived exosomes were found to be effective in a 2021 study analyzing their topical use for skin aging reversal. The company also makes a Vive topical skin serum exosome product that is derived from donated human placenta.


ExoCoBio ASCEplus Exosomes.
ExoCoBio ASCEplus HRLV Lycophilized Exosomes for Hair Growth.

Another well known supplier is ExoCoBio (South Korea). The company’s product for hair loss is called ASCEplus HRLV (Advanced Skincare Complex from ExoCoBio Hair Rejuvenation Lyophilized Vial). It is derived from adipose mesenchymal stem cells.

In May 2023, ExoCoBio was granted an interesting patent related to rose stem cell-derived exosomes (RSCE™) using its proprietary ExoSCRT™ technology. Not sure why someone would prefer roses to humans. Perhaps it is a way to get around government regulations and clinical trials when it comes to cosmetic treatments.

Dr. Sophie Menkes (Switzerland) told me that she uses the rose stem-cell derived exosomes from ExoCoBio for hair rejuvenation with great results (since human-derived is not allowed in Europe). Per Dr. Menkes, she treats patients in five sessions (after microneedling at 0.5 mm), with each session being two weeks apart. Thereafter, you need one session every three months, or else the hair starts to fall out. Cosmetic use (but without injections) is allowed in Europe, including after a laser treatment.

In June 2023, ExoCoBio pubished a paper on its extracellular vesicles (extracted from adipose-derived stem cells) and wound healing. Below is a 2020 presentation from their CEO where he discusses the company’s product and its effect on hair growth.


Exomide for Hair Regrowth.

A doctor from Australia mentioned to me that he is using locally based Xytide company’s Exomide (originally developed in South Korea). On Xytide’s site, it is claimed that this product delivers stem cell-derived exosomes to target skin rejuvenation and hair growth. In Australia, you can only use exosomes topically, so this doctor is applying the product in tandem with microneedling.

Vitti Labs

Vitti Labs
Vitti Labs EV-PURE Exosomes.

Dr. Ron Shapiro told me about Vitti Labs (US) several years ago. They make EV-PURE placental-derived exosomes that are donated by volunteers undergoing C-section. On the company’s website research page, it shows that they have already completed Phase 2 trials for use of these products in Covid patients. They are scheduled to begin Phase 1 trials for a number of health conditions soon, though nothing in the hair loss or cosmetics sector.

New Life Medical Services

I have covered Florida (US) based Dr. Joe Greco many times on this blog. He is perhaps the most experienced provider of platelet-rich plasma (PRP) treatments for hair loss in the US. He is also betting big on exosomes. He sent me the below update:

My son (Joe Greco III, MD) and I are developing protocols, testing and working with the BioScientist at New Life Regenerative Medicine (US) on the “next generation” of exosomes for hair: Dermal Papilla Exosomes (DP EXOS).

Independent, in vivo studies and mouse models, demonstrate that Exosomes derived from DP cells promote hair growth and hair regeneration by regulating the activity of follicular dermal and epidermal cells.

We feel the advantages of DP EXOS in theory are:

1. Cell-to-cell communication: These exosomes carry specific signals that can directly communicate with other cells involved in hair follicle development and regeneration, enhancing their effectiveness.

2. Hair follicle-specific factors: Dermal papilla exosomes contain a variety of factors that are specifically required for hair follicle development and growth. These factors include various growth factors (such as VEGF, FGF-7, and IGF-1), extracellular matrix proteins, and microRNAs. These components can provide the necessary signals and stimulate the proliferation and differentiation of hair follicle stem cells, leading to hair regeneration.

3. Localization and proximity: Dermal papilla cells are located at the base of the hair follicle, in close proximity to the hair follicle stem cells. This proximity allows the exosomes released by dermal papilla cells to directly target and influence the adjacent stem cells, facilitating hair regeneration. Other exosomes from distant sources may not have the same direct access to the hair follicle stem cells, limiting their effectiveness.

4. Natural hair growth regulation: Dermal papilla cells naturally regulate hair growth cycles by transitioning hair follicles between growth (anagen), rest (telogen), and shedding (catagen) phases. The exosomes secreted by dermal papilla cells carry signals that can modulate this hair growth regulation system, promoting hair regeneration.

Revive Exosomes

Revive exosomes are made by a Thailand based company called Regenerative Medicine Ltd. that I just discovered via the below video. Their CEO Brian Dardzinski seems pretty accomplished in the regenerative medicine and stem cell space.

Revive extracellular vesicles are derived from umbilical cord mesenchymal stem cells and currently come in two varieties: Revive EXO-15 (15 billion exosomes) and Revive EXO-25 (25 billion exosomes). The  below presentation is geared towards skin aging applications, but there is some discussion about other uses, pricing, US government regulations and more.


Dermoaroma (Italy) produces an especially unique exosome product called Purasomes HSC50+. The company’s products contain 20 functional growth factors and 20 billion exosomes. Moreover, these are derived from organic bovine colostrum. The cow breed they use are Holsteins from Italian family owned organic farms.

Colostrum (first milk) is the first form of milk that is produced by the mammary glands of humans and other mammals immediately following delivery of a newborn. The Purasomes product also contains curcuma longa stem cells and a unique peptide complex. It supposedly increases miRNA-31 expression by 500%.


Other companies that I have heard about that offer or plan to offer exosomes for hair loss include Novus (US) and Avalon GloboCare (US). However, their sites currently show no specific pages on this particular usage.

More Effective than PRP

A number of hair transplant surgeons have in the past told me that the hair growth results from exosomes are far superior to platelet-rich plasma (PRP). Exosomes contain more plentiful growth factors and signaling molecules for hair regeneration. In particular, those that are derived from embryonic “T-0” stem cells (i.e., placental) have the most regenerative potential. One doctor who saw an increase in dermal papilla cells in some of his patients that were being treated with exosomes even calls them “nuclear PRP”.

44 thoughts on “List of Exosome Suppliers for Hair Loss”

      1. Well I don’t know…AGA is in phase 2, AA only a IND. According to their pipeline.

        Never heard of them. A dark horse, admin?

  1. “nuclear PRP”, guaranteed to blow up your budget and like PRP, no proven results on the vast number of hair loss sufferers except females, very early/young MPB males. Hopefully viable one day, until then another money-grab by the usual suspects.

    1. I am glad you read till the end of such a lengthy post Yoda!!

      The Greco update was added today btw (for those who read this post yesterday).

  2. Had seen the Greco update, another “usual suspect”. Tells a good story with dubious results. To me exomes are another example of polishing a turd (PRP) to show advanced technology to get em in the door. Money is extracted for the treatments itself and then when results aren’t as advertised they try and sell you on a transplant procedure. I know this from first hand experience.

    1. How on earth is using a newborn’s placenta cells the same as using your own blood? It is like saying that hair transplants and minoxidil are the same thing!

      1. Who said it’s the same thing? I’m saying that there’s no concrete evidence that it has any better results. Different ingredients, same s… cake. Unless you know something I don’t? Would love to learn I’m wrong. I’ll be the next one in line for exosomes if anyone can show proof that it works on the average MPB sufferer and regrows hair superior to available treatments.

        1. Here, here. Complete word-salad unless there is solid proof. PRP: does anyone still believe in that wallet draining, blood spiked, roulette wheel of misfortune? Show me one person, just one, who has seen real results and benefited?! Dr Gecko. No thanks. There’s enough of those little buggers scurrying around the walls here in Thailand. At least they’re not trying to sell me BS. Nothing personal to Dr G, but I’d rather head-butt a cactus with my eyeballs. Anyway, I recently slipped on some wet tiles here in The Land of Lies and cracked my head quite badly – so what would I know? I’m fine though kids, a bit foggy at times…but really, don’t worry. However, I am thinking of changing my name to Mrs YoungJet, tossing my Min pills and topical Fin juice and worshipping at the Tsuji temple in Kobe, in the vain hope that some half-baked, ‘hair’ miracle materialises, sometime before the end of the century. Btw: if any delicate snowflakes out there have a problem with the above, please direct all correspondence to my horses a**. Nite.

          1. I got props from Summy K, never know when I post if he might hop on a plane to San Diego and punch me in the snoot! Sorry about the fall, maybe after a soapy sandwich. The Youngjet reference is priceless, did Tsuji ever bring out his line of cosmetic, whoops, I mean cosmeceutical (apparently a big difference even though the FDA doesn’t recognize that as an actual thing) products after his last fail? Hope he fairs better this go-around.

            1. Thanks fellas, appreciate it. All good now, but I’m wary of the sour-faced cleaning lady here after she mops the room. (I think she’s trying to kill me?!)

                1. It’s so-so mate, but I think it was worse before tho. I still have pretty decent hair for an old fart and I’m hoping the low-dose sublingual Min and topical Fin I was prescribed will help, but it’s still early days. Apart from grumpy housekeeping (not that I blame them on such crappy wages and long hours), top lights are my worst enemy! Ha. Apart from hair loss, Covid really knocked me for a bit. For a long time I was quite out of breath. Especially at work. I was getting chest pain, so had my lungs and heart checked – all good. Stress most likely? My doc thinks it ‘might’ be long-Covid, but said it’s more likely a case of taking a bit longer to recover in some patients he’s seen. I seem to be gradually improving overall, so who knows? Glad to hear your hair is making a come back.

                    1. Comorbidities? I got boosters, only got CV19 once with mild flu symptom and unfortunately some hair loss.

                    2. Yes, Admin. Had initial Pfizer shot followed by 3 boosters before I got Covid back in late March. (Attended a spreader event apparently) then had to wait 6 mths before a Moderna booster more recently. Never had any problems at all, but I did hear a tale of one girl in my town who reacted very badly to Pfizer and was bedridden for a week! Everyone is different I guess, but I do believe the shots may have saved me from getting very sick or worse. Who knows?

    1. No patents, no papers; at least for AGA.

      It’s a bit of an odd one. The funding round this year was huge.

      There’s also conflicting information if this is phase one or two.

      I am not overly enthusiastic. But new players are always welcome.

  3. Wait DR tsuji is going to start human trials in the second quarter of 2024 how come no one is talking about this I just found this out . Admin, or anyone reading this what does this mean for us IDs Dr tsuji really going to have his hair cloning technology out in 2026 for half a million dollars?

        1. Only time will tell if they actually start human trials in the second quarter of 2024 . Admin isn’t junji Fukuda trichoseeds going to start human trials at the end of 2024 but isn’t junji Fukuda trichoseeds going to start with a topical treatment first then an injection treatment and then finally actual hair cloning am I right? And if so that means junji Fukuda trichoseeds isn’t going to start human trials for hair cloning until like 2028 is that correct to say ? I’m just asking please don’t call the yoyo police on ma minority we’ve been through a lot!

          1. Marc, you should call Japan and Korea one day and give us live updates for once! Or get the researchers from there to contact me for interviews.

          2. Christ you‘re annoying.

            Just read the articles on this page and you‘re perfectly well informed.

            Both Tsuji and Fukuda will start in 24. That’s what THEY are saying.

            And nobody is talking about Replicel. They are out of the game.

  4. I already have in the past. I contacted replicel/shiesido and one of there student interns let me know replicel has nothing going on and I shared this on here and I was shunned.

  5. This post probably took me 6 hours to research and write.

    I am excited that there are so many different types of exosomes.

    I need to visit a baby delivery ward and try to illegally purchase some umbilical cords (or cord blood) and then visit a cryonics facility for storage.

    1. Appreciate your hard work admin, even when I find the subject matter’s effectiveness questionable. It’s news and might pan out to be something someday down the road.

  6. There isn’t much talk about it yet, but if we want to be optimistic as usual, I believe that a great help in the treatment of baldness will be given to us by artificial intelligence, thanks to AI things can speed up quite fast.

  7. I have a question. As exosomes need to be stored in fridge at about 6-8°C, how can they be sold and transported by airmail without been destroyed ?

    1. Interesting thought, though even something as low-cost as chesse is flown across the US to individual homes without spoilage. So I am sure they have their methods when it comes to the expensive exosomes.

      1. I would like to try exosome as home mesotherapy but if I buy it from website I am afraid of receiving damaged products…

        1. There is a reason that the US FDA is being so cautious. You do not want to mess around with injecting other peoples’ cells into yourself!

          1. Evocyte (exclusive distributors of ASC+ exosomes) say to me that since the ASC+ exosomes are lyophilized, there is no need to store them at 5-8°C in frindge. It is needed only when they have been diluted with saline for injection…
            They also sent me the protocol to use : they recommand 1mm when microneedle mesotherapy is used.
            I will start this next month :-)

    2. I’ve had sublingual Min and topical Fin sent to me by post. They’re meant to be stored below 25C and they seem to be ok. I’m not sure about 6-8C tho? I normally keep them in the fridge. I also bought a gel pouch from glucology to travel with which keeps them cool. That worked great. I think the is a bit of leeway with medicines in terms of temp. It’s a pain, but when travelling you can always ask a flight attendant to put your meds in their fridge or they can give you a ziplock bag filled with ice. Hope that helps?

  8. Are the Pyrilutamide China phase 3 results out yet? Was supposed to finish in Oct?

    I know they r running another long term safety trial but that’s separate.

  9. A lot of exosome products exist on the web. Do you think we can make our own trials ? Which tools would you use it for the application ?

  10. I am using ASCE+ HRLV from 5 months now without spectacular results…

    I just switched to AAPE exosomes for Hair which are from Human stem cells and not vegetable (like ASCE).

    Hope I will get more results :-)

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