Update: June 29, 2023
OrganTech Wins Future Award 2023 for its Organ Regenerative Medicine Technology
Congratulations to Dr. Miho Ogawa of OrganTech for winning Japan’s prestigious “The Economist Future Award 2023“. Per my new Japanese correspondent (old ones were “nosyu” and “Fuji Maru“), this award is sponsored by the “Economist Future Awards 2023 Executive Committee” and supported by the renowned Mainichi Shimbun newspaper agency. There were 225 nominated companies, of whom 15 got awards spread across 5 categories. Dr. Ogawa only became CEO/Director of OrganTech in early 2023.
Make sure to read the detailed interview with Dr. Miho Ogawa that I also posted earlier this month. She started working at Dr. Takashi Tsuji’s lab in 2005 at the Tokyo University of Science when she was a student. Thereafter she joined Organ Technologies, which folded in October 2020 due to fundraising issues that were exacerbated by the Corona crisis.
Now she is back with OrganTech, and I am getting positive vibes yet again for Dr. Tsuji’s hair multiplication work finally reaching fruition. The prior issues with fundraising inexperience and surprise pandemic will surely not be repeated. Japan is home to one of the oldest populations in the world, and also home to one of the fastest clinical trial processes in the world. Especially when it comes to regenerative medicine and anti-aging treatments.
Make sure to keep checking OrganTech’s website for new developments. Per my prior updates, they are aiming to start hair regeneration related human clinical trials in 2024. And they want to offer their hair multiplication treatment in clinics in 2026. I assume they can move this fast due to their past decade of work combined with Japan’s favorable regulations. However, as most readers know, their original goal had been 2020, prior to the earlier mentioned disruptions.
Update: June 1, 2023
Japan: Global Hub for Hair and Tooth Regeneration
An interesting new interview with OrganTech’s confident representative director Dr. Miho Ogawa. It looks like the team is very serious about making Japan the global hub for hair and tooth generation. And they are keen to avoid repeating past fundraising and commercialization related mistakes.
The other representative director is Takashi Kondo (see his recent interview), who is in charge of business planning and fundraising. Ms. Ogawa is in charge of research and development and technology.
Lead scientist and OrganTech owner Dr. Takashi Tsuji remains fully involved of course. The company is scheduled to conduct clinical research within one to two years for practical application. With Japan’s fast track regulations, this treatment could still get to clinics in 2026 as was announced by Dr. Takashi Tsuji last year. Key quote:
“In the near future, this world-first, Japan-originated organ regenerative medicine management will shock the world and contribute to improving the QOL of many people.”
Update: February 11, 2023
OrganTech: New name for Organ Technologies
After ending its partnership with Riken and Dr. Takashi Tsuji in 2021, Organ Technologies is back. It is renaming itself to OrganTech, and this time the founder himself is Dr. Tsuji. A little confusing, but read the next paragraph. OrganTech plans to start hair regeneration related clinical trials in 2024. And yet again they have a new website. They are also getting funding from Kobayashi Pharmaceutical.
According to the latest press release, it seems like founder Dr. Tsuji will remain the team leader and OrganTech is still affiliated with RIKEN. However, Dr. Tsuji cannot be officially titled CEO, since RIKEN does not allow its top scientists to be CEOs of venture firms. This last point was e-mailed to me by a reader.
I previously mentioned how Dr. Tsuji took over Organ Technologies’ debt in 2021 in order to prevent patent loss. He also announced that they plan to offer their hair multiplication treatment in 2026. So this new development means they are on schedule. Note that Japan has favorable regulations in relation to clinical trial speed when it comes to regenerative medicine.
They are also very serious about fundraising this time. On March 6th 2023, they plan to present their technology on Tokyo Innovative Business Day. On OrganTech’s website, it says that the company’s purpose is to “create functional organs.” They they emphasize the two main areas of Dr. Tsuji’s past work:
“Technologies that can contribute to hair regenerative medicine and dental regenerative medicine.”
Also of interest, the following patents are assigned to Organ Technologies. These now belong to OrganTech.
Jan 5, 2020
I have mentioned many times that Dr. Takashi Tsuji and his hair loss treatment protocol holds the best short-term prospects for a hair loss cure. Mr. Tsuji is working in partnership with RIKEN, Organ Technologies and Kyocera. The treatment can come to market faster because 1) It is autologous in nature; and 2) Clinical trials in Japan get finished faster due to favorable government regulations.
All four of these Japan-based partners have their own sites (in Japanese and English). So it is hard to keep a track of new developments.
Organ Technologies and Takashi Tsuji
Organ Technologies has updated its website (Update: They replaced it yet again with a new one in 2023. See upper sections of this post for latest updates). A goldmine of information is available on the new site.
The hair regeneration page has a list of publications at the bottom. Apparently, the company has developed three generations of its technology over the years. Mostly via the work of Dr. Takashi Tsuji and RIKEN (in Kobe, Japan).
I will add more to this post in the coming days, but wanted to start the discussion now. Please only post comments about Organ Technologies and the work of its partners in this post.
I am wondering if human trials has been finished for the 1. generation: DP rejuvenation treatment.
Otherwise SHISEIDO has a big advantage. I could not imagine that SHISEIDO has to do a 2year trial and Tsuji has only to do a little trial and then commercialize it.
I want an official update of Kyocera. They claimed in 2016 on their homepage that they commercialize in 2020. in November 2018 Tsuji said that they will cure baldness in 2020.
So we need an kyocera-Update!
It’s coming. Don’t worry. Just start saving up
bringing out a $300,000 treatment wouldnt be as a worthwhile for a company than a $5000 treatment that they can sell to the masses
Hopefully one of those will be available this year! Glad to hear they have other options and the prices could be much less the other treatments.
This looks very promising. A life without worrying about hair loss. Imagine!
Now this is EXCELLENT information from a company. These Japanese have tackled all 3 areas of its competitors. Sisheido better stop messing around or these guys will take them under. I still think it will be out of reach for common folk due to its price 300k but……if they announce completion of any of the three treatments they technically cured baldness. I’ll take a loan out to end this bs mpb once and for all.
Which of the three treatments do we think will be best for diffuse thinners?
Also, what is Organ Technologies relation to Tsuji?
On the page they mention that they continue R&D and anticipate clinical trials. Too bad thought they were undergoing trials in humans already. this still sounds like it’s sooo far away:/
Tsuji started human trials in 2019 per last update.
Has this been confirmed and do we know which of three technologies mentioed are undergoing trials?
No it has not been officially confirmed unfortunately
Hi Admin, first thank you for mentioning me, that’s kind. I knew you would make an article (or more articles) out of this new information as this company is our biggest hope and the by far most advanced in terms of time schedule and technology.
How do you know they started human trials already? Any official statement?
Anyhow I believe they started secret testing long time ago, probably in 2018. Those claims on the website are so strong and confident, they must know it works – otherwise it would be terribly embarrassing.
Hi Ben and GreedBlocksTheCure,
— Per this interview (I did not recheck the video today so please do so), human trials began in 2019:
https://www.hairlosscure2020.com/dr-tsujis-hair-loss-cure-in-2020-will-be-costly/
— Per page 2 of this interview after translation, human trials were scheduled to start in 2019:
https://project.nikkeibp.co.jp/behealth/atcl/feature/00003/061200009/?P=2
I would be surprised if they are behind schedule, since this is an autologous treatment.
I see now. They were doing clinical research at a university hospital during 2019. The clinical trials for product approval will begin after the results of the research are submitted.
@admin according to their last official post from 2018:
” Under the plan, we will begin manufacturing samples for preclinical testsinJuly2018 and we will conduct preclinical safety tests using animals.Weplan to complete the safety testingin 2018.If the results of the preclinical safety testsare successful, we will apply for clinical research to the Certified Special Committee or Certified Committee for Regenerative Medicine. After receiving approval fromthe Committee, we will present aprovisionalplan to the Minister of Health, Labor and Welfare,and will shift towardimplementation of clinical research.The details of the clinical research will be announced before the initiation of theresearch. ”
But, there is no official announcement about any clinical trial.
Histogen made similar claims about time lines, FDA in The States average 17yrs for trials and market phase. Ill remain hopeful but expect the worst, 300k is ridiculous but perhaps there will be licensing and more affordable options of it does indeed make it to market
On Linkedin there are only 6 people who say in their profile that they are working for Organ Technologies.
Which means they have 6 employees looking for another job :-)
Linkedin is more for business professionals, not medical researchers.
They had 11 employees in mid-2018. Many Japanese professionals probably don’t care about LinkedIn.
https://www.mitsui.com/jp/en/release/2018/1226500_11215.html
Replicel has 4 employees Linkedin lol —
https://www.linkedin.com/company/replicel-life-sciences-inc-
Unfortunately, I have to ask the question… Are these companies seeking investor money? Companies make beautiful claims when seeking investor money. What’s motivation for website claims without proof or an available product? Just tempering expectations a bit.
Photos. If these claims are legit (good chance they are), then I sincerely hope we see photos soon. That’ll be the moment. Let’s hope these companies have done it and they’re good, honest people.
Videos, not photos, should be the minimum standard of proof. My first question when I see before and after photos is often is it even the same person?
Even people in Africa have video phones now. There is just no excuse for not taking a video.
good, honest people!!… what’s that??…
It’s about money… good and honest it’s not part of the deal…
But we still hope for the best…
Histogen os the cute guys. Wait and see. Is near! Wait a bit longer and you will have full head of hairs!
They have funding from Kyocera, Mitsui, Itochu, RIKEN (Japanese government) and probably more.
Admin, forgive me for the skepticism. I’ve been lied to by the hair loss industry since I was 19, and the results have been particularly rough for me over the past 20 years…
I once knew a very reputable HT doctor who claimed a 70% growth rate with his brand new hair follicle generation process. He used that promise to get me to agree to another hair transplant surgery (my 4th) plus his new hair regeneration procedure to supplement. That said, he still wanted standard FUT to make a predictable and artistic hairline, but he was to fill in the crown with his new breakthrough procedure (I drove 9 hours each way to see him.. twice). I agreed to his plan, because I was desperate from previously failed FUT procedures, and the doctor knew it. Again, he had a great reputation for hairlines, so I trusted him on the FUT in the front and new hair regeneration process on the crown. It made sense. He took my money.
This doctor is a well-known name in the HT industry even to this very day. He presented a very lengthy and beautiful PowerPoint presentation at a national hair conference showing microscopic photos of new hair follicle formation through his breakthrough process. I now know that the point was to attract desperate people like me to his office.
Needless to say, the new procedure failed. The new follicles were a lie. I now have linear FUT scars on the sides of my head that have left me no other choice but to cover it with a wig every day, costing me thousands of hours, thousands of dollars, discrimination against me at work, and no personal relationships (since I refuse to impose my daily stress on anyone).
This doctor named that fake cure “autocloning”… plucked hairs plus Acell.
That’s enough venting for one day. I know the past doesn’t predict the future, and I visit this website with hope each week. I just also hope that my story might help give people’s optimism a healthy dose of caution and critical thinking. Doctors can pretty much claim whatever they want, and they tend to do so if it helps the money roll in.
I understand Slick, and hope things improve for you. I want to stop wearing a cap so often myself. Not to mention needing haircuts every 4 weeks due to various regions of the scalp misbehaving.
this guy got me too..back in 2009 …shaved my head, got smp…to cover my scars…after lasers to smooth and flatten the scars.. concealed my scars about 70 percent in 2015..this doctor charged me…for the test and never called me to see if the beard hairs grew.. the beard hairs never grew back either..there is a circle in my mustache..where he plucked them so hard…lol
First of all, Dr.Tsuji is not professor and scientist on some marginal university in some rural Thailand town. He is professor on one of the best universities in Japan. Japan is highly advanced country and Japanese are very hardworking people. So, don’t worry, he is not gonna lie if they failed to produce cure for MPB.
Don’t sugar coat it :-) You mean he is not from a university that used to be a truck stop.
That’s nonsense, Tokyo University is up there with the best universities of the world (https://cwur.org/2019-2020.php)
I think you may have misunderstood what I meant. I was not ridiculing Tokyo University but most of the others.
And I have been to Japan and it was awesome.
Dr.Tsuji is scientist with very big credibility and his team is working on many other organoids. Not just hair. In future all these treatments and innovations will bring very big positive things for japanese economy and health. Everyone who had visited Japan knows that they are very credible people.
if he fails then he commits suicide, is an old Japanese ritual \ use.
Hey Slick, sorry to hear about your experience. Hair loss industry is a giant scam. I personally like it when people vent on here. It’s good to hear it so others can learn andnot fall for ht and other scam doctors. Was this doctor Rahal? I know he is big on fut hairlines and known for impressive results but it’s all advertising. I hear other complaints from that Prasad guy who is pushing his advance prp. Haha dude screams scam. They all need to be called out. Not sure why so many forums block the names of these ht scammers. They need to be accountable for their actions for taking advantage of innocent mpb sufferers. Better off not getting an ht from a crook and go bald than have a failed one with scars and blowing thousands. So much for the fda tracking these guys down. It’s all about money ….always about money.
Thanks Mjones. I found a great micro pigmentation artist who is slowly helping me mask the scars with a buzz cut, so I’m hoping that’ll help me ditch the life-sucking wig and makeup routine. The SMP is subtle, unnoticeable, and effective. I do take some responsibility for bad choices and am always working on a “fix”. Moral to the story is NEVER get FUT scars. My life would’ve been far easier had the most recent scam not sold me on getting scars on the sides of my head which are very very hard to hide.
The doctor’s name I won’t say, but searching autocloning acell and plucked hair might get some results from good ole 2010. He was really onto something working with intercytex! LOL. The PowerPoint presentation really sold me on traveling to see him. Desperate people make bad decisions, and HT doctors take full advantage. You just have to keep moving forward and try to have a better plan.
Slick
Reading your story, I feel deep and honest empathy with you.
My personal struggle with mpb has also caused me to isolate myself, socially and relationship wise.
I also feel ridiculous lucky that I’ve been able to dodge several transplants – that I know would have been disastrous. The first one 20 years ago (when I was around 20) with a local doctor would have ruined me for life.
I was so close, so reading your story really hits home, because it could very well have been me.
Honestly, I truly hope there will be something that actually works within the next five years, so that people like you can finally find some healing and peace. I, with my NW3, will gladly get inline behind you, as you deserve this so much more.
Telly, Your comment is greatly appreciated. I’m pretty much max NW. That said, at your NW 3, it’s possible that FUE and some subtle SMP could help you. Regardless, it’s best to embrace it and clip your hair nice and short. Men look the strongest when thinning hair is clipped short. Embrace being a guy with too much testosterone! Women have told me they liked when guys clip hair short, because it makes them feel more girly by comparison.
Anyway, I WISH I could clip my hair very short and just move on. Unfortunately, FUT scars are long and embarrassing all around my head. I refuse to be a walking joke, so I cover them up (particularly at my job as an engineer, I speak in front of big crowds sometimes). We all have our issues to deal with. It’s certainly been humbling and isolating as you say.
Best wishes to you. I’m very glad you never got strip scars! Maybe you can buzz it short until we get the cure!
Sounds like you are speaking of the MD in North Carolina, but that seems odd considering his stellar reputation?
“live your life” Yes, I thought the same thing! He’s a hardworking MD that takes pride in conventional HT hairlines. You feel you can trust well-known industry leaders, right? I did.
But ask yourself, given that we have nothing better than finasteride and minox in 2020, what business does anyone have naming a 2010 procedure “autoCLONING”? What does that imply?? How does a doctor get away with such colossal BS and still keep a “stellar reputation”?? He claimed 70% success rate of new follicles in a written presentation… BS… No consequences
The whole point of the scam was to draw long-distance people like me, with no hope left, into his office where he could convince a scarred, max norwood guy that there’s still hope and that I should pay thousands for even more procedures. That’s the evil of the business. There was still money to be squeezed from me. I was desperate after failed hair transplants and being a high NW beyond any surgeon’s capabilities. He knew it. He used it.
Even the most reputable names in the industry have no problem running scams based on hope and hype. They’ll give you life-altering scars knowing full well they can’t really fix your hair. It’s all about the money.
Yeah that Dr in North Carolina talks a lot about innovation but I never see any real WOW factor results from prp or his transplants. The best fue I see are from Spain. Fue experts, and some good results from hassan wong, rahal and Konior. I see great ethical reviews from konior and great quick healing from his patients. Hopefully we will see cell based transplants this decade and remove the need to butcher our heads.
Mjones.. LOL… Hype brings clients from far and wide! They can claim almost any new, unprovable “developmental” breakthrough is working with no consequences (if it doesn’t work for YOU, then you’re a unique case). You only find out after you’ve paid. So what’s the latest snake oil? Exosomes?
I google Acell hair auto cloning and at least 10 doctors refer to it as autocloning or auto cloning on their sites….! Based on some paper about Acell. What a scam.
North Carolina
Hey Slick, you can say his name no problem, and sorry to hear about your bad experience :-(
Admin, Okay I’m done spamming your site with my scar-head origin story. It helped to share. Now I’ll stay relevant to the topics and hope for the best moving forward! If and when we see evidence of a breakthrough, I might just appreciate that a bit. Thanks.
No worries, I trust long time posters’ feedback. Were your scars largely from your earlier FUT, or from the most recent one?
Original scars in back of the head were from Dr. Shapiro in South Florida. He had big-time radio ads running the Miami-Fort Lauderdale metro area. I was 19 years old and showed him photos of my NW7 grandfather to see if that’d be enough hair to work with, and he told me the results would be “miraculous”… Had 3 surgeries over consecutive Spring Breaks. Result was sparse plugs and cratered scalp.
Many years later I was searching for any solution to fix hairline, add density, and ditch wig (buzz shorter). That’s when Dr. North Carolina had the plan of supplementing new FUT from sides of the head with his new “autocloning”. It made sense at the time, since Acell was supposed to make scars almost nonexistent (per the PowerPoint presentation) and I was desperate. The side-head FUT decision I blame more on myself, since I was then an adult. Regardless, I was lied to about autocloning and was flat-out told that it was working very well. I wanted to believe in a reputable doctor. Didn’t work out.
The scars on the side of the head make SMP masking much more difficult. It’s a highly noticeable location when facing people to talk. My hair is too thin to cover them without makeup. Sucks.
Anyway.. I’m ready for a real solution. Hopefully we see some results.
Hairclone received full funding!!!
We’re on course gents
Tsuji hairclone Tissuse and distant chance shiseido on the line up!
WOO!!
Assuming they do more than just follicle banking in the near future, it is good news.
https://twitter.com/Drgregwilliams/status/1213147107147866112
They hope to be able to offer treatment early next year, maybe earlier if things fall into place smoothly.
ive met with 4 of their clinical partners, 2 face to face. the other two via skype. i believe we will have other treatments that prove more robust soon before they launch. conincidentally, i am meeting with Cooley on Friday and will ask him about hair clone. however, he is really high on exosomes right now….so should make for an interesting meeting
Please post your experiences with exosomes on here, and say hi to Dr. Cooley from HLC2020 :-)
Ok, but that Tweet I linked to before from one of the UK doctors only mentioned follicle banking. Hopefully they can speed up the more important work.
Here it is:
We are extremely pleased and proud to announce that, in partnership with Newcastle University, we have received a significant grant from InnovateUK to help us develop our personalised regenerative cell therapy for androgenic alopecia and make it ready for clinical use
https://twitter.com/HairClone/status/1214209264539045888
Only interesting for our children. I’m following this blog since I’m 23, back then I was hearing news about the „big players“ that were supposed to have a cure by now according to their timeline and I always thought to myself nice, I’ll just focus on studying, maintaining a good lifestyle and physique and by the time I finished university and found a job, I’ll finally enjoy life again having hair like most people around me. Hitting 28 soon and nothing has changed, not even speaking about available treatments but also potential treatments. The biggest innovation is follica, combining microneedling with probably minoxidil
@Red
I started to deal with baldness when you were born… believe me you are not in a bad spot…
I remember when I was 18 and started losing hair and they said a cure was within 5-10 years away. There was equal hype back then but it feels like they are maybe half way there since then. I’m turning 30…so at 42 maybe I’ll have hair lol. Who honestly cares at that point. At least I’ve been alright with buzzing my hair with a 0 and 1 since I was 19, not some guy messing with my hormones or butchering my scalp. So I’ve been fortunate there. Besides random comments and questions if I’m in the army or a neo-nazi, it’s alright.
For what is worth here is another article….
https://www.wraltechwire.com/2020/01/08/a-cure-for-baldness-durham-startup-says-yes-with-its-patented-led-light-technology/
Just interesting to read…
https://www.theguardian.com/lifeandstyle/2020/jan/08/it-takes-a-thick-skin-to-rock-a-bald-head-meet-the-women-embracing-hair-loss
If that same north Carolina doctor is involved with hairclone then my excitement for that company is now gone. I really hope these researchers actually understand the stress we go through and that scamming us or providing false claims is not cool. My gut tells me that this treatment will provide sparse new hairs and nothing close to a cure. Prob best case prp results. Of course im pulling this out of my a%* but I just don’t trust that company. Failed intercytex researchers with a scammy ht doc already promoting autocloning. Doesn’t sit right especially when they asked the public to crowdfund them lol. Even follica didn’t have amazing results at least he didn’t put up a go fund me account lol.
Biologist find 5x increase in life span
For c elegan “applocable to humans”
Also sinclair has new interview saying their working on full tissue age reversing at Harvard with george churchs lab.
I will only trust anti-aging gurus when they regrow hair in tandem with aging reversal claims.
This is a lot bigger than hair. In fact I’d encourage anyone stressing about hair loss to dive into all of the exciting stuff going on with life extension and age reversal. It’s given me a genuine peace of mind.
Well hey It’s not easy becoming a chief scientist at Harvard… just hearing two of them saying their astounded by what they’ve discovered in the past 6 months is obviously note worthy.
These studies are totally correlated with yuva mitochondria take on the situation btw so I think it’s much more worth attention.
Not to sound elitist but you know it’s a big difference between these hair loss companies vs Harvard.
Can you post the link to Sinclair interview Egghead?
It’s on YouTube it’s recent sorry I’m too lazy / busy
Hello Gents,
Probably i’ve missed that but Tegardong this new technology: after new follicles will be cultivated in the lab and and send back to the doctor is it going to be good old regular transplantation? Similar to FUE procedure?
Tired of hearing about all the hairloss and age reversal break through’s. Nothing ever comes to fruition. Most just want the publicity.
Age reversal? It’s gonna take decades no need to be on the edge of your chair. Their doing clinicals in 2022 it’ll be alot longer than that until they can turn a 60 yo into a 20 yo body. Even ray kurzweil as aggressive as his exponential time lines are is 2040.
If libella succeeds this year starting next week dr. Bill Andrews work is being put to the test with controversial coverage. If they succeed then you’ll be hearing about this more than trump. That’s not likely to succeed though according to other scientist.
Admin,
I contacted Organ Technologies to ask some basic questions, and they responded. Here is their response:
“We are conducting research to provide patients with our technology as you have expected.
The method of recruiting clients and clinical trials or subjects are undecided now.
We hope to confirm our progress on our new HP new arrivals and media etc.
I am sorry to hear that you will respond to your expectations,
but I would be pleased if you can understand it.
We will encourage our employees to use words from you
and we will make every effort to realize it as soon as possible.”
Sorry for posting this on an “old” post (not even on the first page) but I wasn’t sure where to put it.
Thanks Paul! Greg got a similar reply too. Other sources suggest they started trials last year. Hard to tell if Tsuji and Organ are on the same page and being transparent.
Well it’s basically neither a bad nor a good reply, and probably a standard generic text, copy and paste. I wonder how many enquiries they get, must be thousands a year.
It’s clear that they don’t want to give any promises and hold expectations down. There’s always a chance of failure – maybe the technique just doesn’t work in humans (mice it does).
What’s true is that the official statments (Tsuji Interviews, Organ Tech Website, RIKEN) are sometimes a little contradictory or confusing – the website for instance is pretty direct and audacious and claims a “global breakthrough”. Other statements are more cautious. The translations from Japanese to English also seem to be a little wooden at times.
No worries. Do you think we will learn anything significant in March?
Greg, did you follow up? I didn’t bother, as they didn’t really answer any of my questions, and I thought I’d just get a similar reply to the first one.
Nah, I didn’t. Although they usually do give updates in March. I think that they’re not telling us anything real about their work because those inquiries can come form anyone. Only months ago they were giving lectures and interviews about their treatment so I wouldn’t take what they said as super crucial – they could just be avoiding disclosing anything of importance.
Very interesting. I guess that this treatment is for people who are completely bald and not in the process of balding? Unless you could do multiple surgeries but with the price that seems unrealistic.
From the information their website, they claim that it doesn’t matter at what stage you are – they have the treatments to fix it.
meaning even If I’m only a norwood 2-3 it can restore me back to a 0 forever? I’m confused how they would be able to do this with out multiple surgeries if I am certainly gonna lose more hair
I don’t think it’s multiple surgeries but then just doing multiple procedures with your follicles in the lab.
But how will they stop the rest of the hair from falling out?
I think their “first generation” procedure dies that – I think it’s similar to Shiseido’s procedure or what hairclone is trying to do – it DHT-proofs the hairs that you have. And the second gen. treatment clones hairs and fills up places in which you don’t have any. Check out their site – all this info is on there.
Whats the difference between what riken is researching and what jhewitt is?
Oh that’s awesome. you really think this is it? I can’t wait to not worry about this anymore.
They definitely claim to so some amazing stuff. I guess we’ll find out this year with trail results – but yeah. A lot of people – both on this blog and other blogs and other places as well refer to tsuji as one of the “imminent cures” that are being developed. And while there’s no tangible proof to back that up yet, there is a very good amount of evidence.
Only downside is the price during the first few years. Then it should drop to be somewhat affordable but still pricey. But it’ll spark competition – like TissUse who’s already playing ball – and others and create variety so you might be able to get a very similar treatment that’s in a much different price range.
When do you think we will get news about it? in 4-6 months?
Tsuji or TissUse? TissUse should be starting their trial in late January – so any day now. For tsuji, nobody really knows when they’ll do an update but they usually give an update in March so there’s a good chance they will this March as well.
I assume TissUse will have another delay… unfortunately
Jon Knight had problems with the company which should do the trials. As we are in end of January and the trial haven’t started I think we can forget TissUse for the next months
Time to buy stock in riken?
Corregidme si me equivoco, pero todo esto no fue noticia en 2018?Según lo que había leído en articulos de tricologos, los resultados en humanos habían sido malos y aseguran que todavía es una utopía la clonación capilar.
Ojalá no sea así. En qué os basais para esperar buenas noticias este año?
But how will the business model thrive if they’re charging $250K plus? They’ll have a decent amount of customers initially then it will fizzle out shortly afterwards and won’t sustain. However, this does cause a healthy pressure on other hair regenerative biotech companies to pick up the pace.
All relatively new technologies and innovations are very expensive.
This treatment will be very expensive, because it will give long time real solution based on science and technology from leading worldwide institute (RIKEN).
And this is the closest that we can get for hair cloning in near future. All other treatments are part-time solutions or only lab based dreams so far.
Hopefully, they got a chance to test the treatment and improve the technology last 2 years.
Bryan Bryan Bryan ♂️
Time to update GT20029. Much much more promise than the company listed above.
I already updated the Kintor post in the GT20029 section. Please try to post in that subject’s related post.
Thanks admin for the update but I don’t want to get my hopes up anymore. I don’t care if this cost so much money as long as it comes out to the market, I hope this isn’t a cruel joke. Bryan bro if you read this, do you think Dr tsuji hair cloning is better than stemsons therapeutics ? and do you believe that Dr tsuji will be able to release his technology to the public in 2026 ? And if this will be 250k plus what if one just needs to fill in one’s temples? That’s only like 1000k hair grafts generally speaking,so will 1000k hair grafts really be 70k dollars ? If so people have spent way more money on a Lexus than getting there looks back a good hair line does amazing thing’s to one’s physical appearance. Confidence is a key component in life.
After clinical trials we will know which technology is better. Until then we must wait.
OrganTech got their first funding and if they get their second funding in March, then they will firstly get to clinical trials in 2024. It will be game changing and it will open doors for other organ regenerations, because hair follicle in his nature is very complex organ.
Stemson is working with iPSCs and they are still many years away from clinical trials, because USA laws are different than Japanese.
@ Bryan your right! Thanks for the information.
Well what a nice surprise. Tsuji is back, with a vengeance. Nice find, admin.
Just a few short years away, hair cloning (Stemson, Tsuji, Fukuda, Hairclone, TissUse, Stemore) was seen as THE future solution. Today we are not much further – but trials are announced so here’s that. Eventually it will happen.
This approach is very complex: you need to serve 2 clients: patients and clinics. It’s more of a tech-business than a pharmacological business. So those ventures must deliver high-tech and know-how to thousands of clinics. Absolutely possible, but I wouldn’t underestimate the size of this endeavor. Traditional hair-transplants might be gone forever in 10 years.
But the bigger threat for cell-therapies is that traditional interventions (pills, injections, topicals) gained a lot of traction in recent months and seemingly offer full solutions for hair loss and are much easier to apply for the patient himself and also from a suppliers perspective. Pelage, Amplifica, HopeMed, Kintor, Olix – every single one of them could solve hair loss. No transplants needed.
If cell-therapies want a market-share, they need to move quickly. Ask yourself: would you rather take HMI-115 or go to a transplant-clinic?
A lot of competition in the market, that’s good for us.
Pills, injections, topicals will have limited success and you need to repeat treatment over and over again.
That would be so great if a company like Hopemed could cure bald scalps without a transplant, but I am reminded by some dermatologists that once the hair follicle gets too small, there is no coming back. Do you agree? Is there any science saying differently for human hair?
The stem-cell-reservoir is always there. Many studies showed that if certain signalling-pathways are activated the follicles fully recover – they are just dormant by definition.
This approach is done by Pelage (directly stem cell) and Amplifica (signalling pathways).
HopeMed also showed full regrowth (in previously fully bald areas) in the studies – but that mechanism is a little different (prolactin).
Androgen receptor targeted therapies (Olix, Finasteride or Kintor) are not very effective in that.
Thanks Ben. You seem to know a lot. I appreciate your reply and taking the time out to do so.
Man I hope your right!
The best news of the year without a doubt, although with Tsuji we must be cautious given his history. Reading your comments, I have to agree with Bryan. All of us who suffer from alopecia, once did not have this problem in our minds and I consider that a solution based on pills, topicals or injections from time to time would not solve our psychological problem of not worrying about baldness forever (although I understand your reflection Ben, that this path would be more affordable in economic terms). And as a final comment, I have read studies that explain how DHT affects the dermal papilla, opening small pores through which the stem cells escape, turning into skin cells, so in a person who has never been medicated against alopecia, and have a large area of baldness, it is impossible for me to make new hair sprout, without a definitive solution such as hair cloning.
the more the merrier but maybe all these companies will be too late , because im beginning to think that verteporfin might be the real deal, Dr Baghoutis small trial so far has shown that hair follicles regenerate, he was able to achieve 100% regeneration plus wound healing after extracting a single follicle. We need more hair transplant doctora doing experiments with verteporfin to see if they can replicate these results on a larger set of follicles. While i think hair cloning will be the permanent cure, this could be an interim treatment to have essentiallly an unlimited supply of donor extractions. Admin, you should follow Dr Baghouti i can post a link to his thread if anyone is interested.
I was never keen on just one surgeon testing. Hope it can be replicated. Also, please post about that in the below thread:
https://www.hairlosscure2020.com/verteporfin-week-in-the-hair-loss-world/
thanks will do!
Once they show a legit nw6 to nw1 then I’ll get excited…..I know how this all pans out….I hope tsuji shows us a real hair cloning solution…
I don’t need a NW6 to NW1, just infinite hair, rest will be done somehow, even if it has to be done in severel sessions
We need as many hair multiplication approaches to be commercialised as soon as possilbe: that will bring prices down. There has been speculation that Tsuji’s method may initally retail as high as 300K dollars: well, we will see. It has to be proved to work and be safe first. But anything like that will obviously be out of the question for the great majority of people. All new technologies are expensive to start with: it takes the magic of competition and the market to bring down prices and make it accessible to the mass of people. I’m now wearing hair systems (I no longer have enough hair for a transplant). I live in hope that in ten years or so I can get bio hair back. It will come: just a question of time.
I think this will be the first real cure, and it will be available in only 3 short years. Fukuda will be probably as fast. When you think of it, it’s even more than a cure: you could have more hair than you had as a 16-year-old: denser, lower hairline, etc. An endless supply.
It’s pretty clear though that it will be expensive and there will be only limited numbers of patients. At least in the beginning. Having two strong contenders is crucial therefore.
The third in the game, Stemson, is a bit of a letdown. They are soon entering their 6th (!) year of existence. They started with following statements:
„Our new protocol described today overcomes key technological challenges that kept our discovery from real-world use“
„Now we have a robust, highly controlled method for generating natural-looking hair that grows through the skin using an unlimited source of human iPSC-derived dermal papilla cells. This is a critical breakthrough in the development of cell-based hair-loss therapies and the regenerative medicine field.”
So they had the tech already in 2019? What have they done since?
It’s certainly not an easy task, but still a major disappointment. I hope they come up with some big announcements soon, or they are the next failure.
And I interviewed Dr. Terskikh in 2017 and covered his earlier work in 2015!
Exactly lol people don’t realise that Terskikh has been in the game longer and only now talking about clinical trials. But I do agree I feel like 2026-2028 are going to be special years.
I would have to double-check, but if I remember correctly Terskikh‘s first papers regarding hair research are from 2011. Let that sink in.
I’m not so convinced yet. We know Dr. Tsuji got it to work in mice (so did Stemson Therapeutics) but now from mice jumping to humans? With the pre-clinicals it seems that going from mice to a bigger mammal (and one with more similar skin to humans) is the barometer to see if a therapy is likely to work. Did Dr. Tsuji do that and I am just not aware? I was happy that Epibiotech succeeded in their pig studies but am not happy that they didn’t allow for longer periods of time to see if the hairs were able to cycle and regrow. Unfortunately that is a process that takes years of patience. I hope they will try again with this approach. The thing I’m worried about is Dr. Tsuji might succeed in growing hairs in people but then the hairs will fail to cycle continually in them.
So there starting human trials next year maybe the following year? Do you think we will be notified if and when Dr tsuji starts human trials? Do you think Dr tsuji is really going to do this for 2026?
The end of hair loss will happen one day, that I don’t doubt, but when…who knows? Ask ChatGPT before it takes your job. Obviously it’s just plain speculative at this point. Maybe in our lifetime, maybe not? I’m hopeful that one of these players with a card in the game will crack the riddle…eventually. Soonish would be better (I’m not getting any younger). In the meantime, it’s oral Min for dinner, quickly followed by a topical Fin nightcap and a sneaky Niz chaser. Nite.
What do you think about HMI-115?
Marconi, to the best of my knowledge it’s effectively the cure. Will cost around 80K usd however.
I always wonder where people always get this extreme price estimates from? There was never any offical mention regarding the price… Some antibody treatments can be this expensive but that doesn’t mean this one has to be that high. I was treated with antibody injections a few years ago and the injection price was much, much cheaper for example, only time will tell how expensive it will be.
No offense, how do you know it will effective?
Leon Edwards.
What a stupid comment. The treatment isn‘t out for years to come, yet random users on the internet know the price.
Ludicrous.