Major Development — Kyocera Branches out from Electronics into Hair Regeneration (Aims for 2020 Product Release)

Update: RIKEN added a brief summary of this development on its site and included the below photo on its home page:

Update: Commentator “sets” e-mailed Kyocera and got a response:

“Hello. My name is Hina Morioka from the Corporate Communications Division at Kyocera Corporation. Thank you very much for your question about our research with RIKEN and Organ Technologies.

Regarding timeline, we aim to put the technologies into practical use and make medical treatment available in 2020 in Japan (medical treatment at one’s own expense).”


I was planning on publishing an entirely different post today, but things continue moving along rapidly in the hair loss research world and you regularly encounter sudden usually pleasant surprises.  In the last post, commentator “Lewa” just brought to my attention that major Japanese electronics manufacturer Kyocera was entering the hair regeneration market via a collaboration with the government-affiliated RIKEN Institute in Japan (where the renowned Dr. Takashi Tsuji leads the hair related research department) and Organ Technologies in Japan (a company in which Dr. Tsuji is one of the directors).  In that article, I read that they plan to commence clinical trials BY 2020, but that they also planned to start their business IN 2020.  They will develop prototype equipment by March 2018.  Very ambitious and rapid progression targets, but if it can be done anywhere, it would be in Japan where the government is very supportive of expediting research.  With the addition of Kyocera into the mix, Dr. Tsuji now has access to funding that all other hair researchers around the world can only dream of.  The only other hair loss cure research related company with this kind of funding access is also based in Japan in the name of Shiseido.

At first I was only intending to mention the above development in my once a month “brief items of interest” post.  However, then I discovered an even better version of the above article on Kyocera’s website. This second article is far less ambiguous when it comes to the dates and therefore this development deserves its own post now.  Key quotes from the above second article:

“The companies aim to put the technologies into practical use in 2020.”

“Kyocera, RIKEN and Organ Technologies plan to establish cell culture and transplant technologies and develop devices for transplantation, aiming to put the technologies into practical use for the treatment of human alopecia in 2020 in Japan.”

Update: Forbes magazine now has a story on this news too.
Update: A brief Japan Times summary.

The division of labor between the partner companies will be as follows:

Kyocera = Development of cell processing devices via the utilization of its microfabrication and manufacturing technologies.

RIKEN and Organ Technologies = “Development of stem cell culture/amplification technologies, development of cell manipulation technologies, establishment of production processes, implementation of preclinical studies, etc.”

The technology (“regenerated follicular primordium” via a combination of epithelial stem cells and mesenchymal stem cells) being developed is outlined in the bottom part of the below image taken from Kyocera’s press release.  Top image shows a modern day FUT (strip) hair transplant procedure with limited donor hair supply limitations.

image: Development of Medical System for Hair Follicle Regeneration

294 thoughts on “Major Development — Kyocera Branches out from Electronics into Hair Regeneration (Aims for 2020 Product Release)”

  1. This is perhaps the best news ever for hairloss sufferers.

    Yet I cannot help to believe that the 2020 timeline is far too optimistic. Asking them for timelines at this point is like asking a hockey player of he believes he will win the next game.

    This is by far the most serious possibility of a cure that I’ve ever heard of. These are top scientists from one of the best universities in the world, and a big company is in as well.

    Reasons to celebrate? You bet: they could very well have a cure. But don’t stop breathing just yet.

  2. Who knows how many years it will really take to perfect the “stem cell culture/amplification technologies”. They shouldn’t give us even a tentative timeline unless they have already succeeded in cloning cells and only remaining tasks are some paper works and legal issues. How can they predict when this will come to fruition? “We’ve been failing for the last ten years but just need four more” is that it?

    1. @FADI, no this does not contain Sh-polypeptide 9. As far as if they work, based on simply what they are, growth factors, yes one might hypothesize that they will work.

      This article posted below has sparked my interest, and I’m curious as to why further studies were not performed. My guess is that AGA is not life threatening, and getting grant money to perform such studies is difficult, so the treatment was not investigated more.

      http://www.des-company.com/wp-content/uploads/2014/05/Zimber-et-al-2011.pdf

  3. admin in an italian hair loss forum they gathered questions and sent them to brotzu and he replied… , can we try with dr tsuji ?

  4. @Paul: Kyocera stock price is up. see the link

    https://www.google.com/webhp?sourceid=chrome-instant&ion=1&espv=2&ie=UTF-8#q=kyocera%20stock

    @bw: another smartass scientist we have here.. Of course u know stuff better than Dr Tsuji. These comments never cease to amuse me..
    If u ask Dr Tsuji his name.. he would first check his ID and then reply to you. Do you understand? He is the most conservative tight-lip scientist ever and never talks gobshite.
    If timeline is given, then it is logical. and i believe it can only be made sooner…

    I am sure Admin is now busy with collecting his questions to Dr Tsuji.. hopefully we have a chance to make small interview with him.

  5. My guess is they already have successfully cultured and developed the stem cells/ follicles. They are just trying to understand the effects when they are transplanted, hair cycles development etc.

    Or more thank likely I’m entirely wrong…

  6. ok this is just my speculation… on top of what u say (stem cells already cultured and developed). I BELIEVE they made a quick test on human and seen it worked.. Otherwise Tsuji will never ever never ever agree with such tight timeline.

    Of course Admin will ask this question and of course he aint gonna reveal what is cooking in the kitchen.

    We know Dr Tsuji by now. He takes every question with a grain of salt.

    like i said, also Hellouser thinks same, this is done deal. in next 4-5 years fin minox and HT surgeons will go down the drain…

    1. If they don’t improve their industry with hair donor regeneration… maybe you are right. But i’m not sure about that.

  7. The pictures released only showed fuzzy wiry type hair on a mouse however. The major issues stopping hair cloning was the culturing and then the actual hair cycle growth if I’m not mistaken.

  8. It’s always 5 to 10 years away. Tired of these timelines. Tsuji needs to show amazing pics then I will get excited or its just another company sending empty promises. Plus in 4 years half of us whose hair isn’t maintaining anymore of current treatments are going to be nw5 or more by 2020. We need something now that is better than current treatments. 2020 is too far away. Tired of fking waiting!

  9. @gatsby, exactly we still have to see some results. Like I wrote earlier – this COULD be the treatment to actually cure HL for good. I wonder if these news could put some of the other companies on fast track?

  10. ok guys and u tell me… why all of a sudden Dr Tjusi , aka the most conservative scientist in hair loss industry is joining his forces with RIKEN and showing us 2020 timeline?
    can someone explain it to me? why now? why he was silent before?
    and please dont be just smart ass sciencisit like PRAY THE BALD AWAY in bht and hairlosstalk and try to challenge the guru.

    just go relax and enjoy your 4-5 years of baldness .. look urselft at mirror and smile… u all know these days will be all over soon

    1. I think that’s just business. Spilling their beans early doesn’t help if they’re out to make as much profit as they can. On the other hand, there’s always a lot that can go wrong with treatments that haven’t yet been proven 100% effective, safe and feasible.

  11. @brah

    Not my intent to “jump” on derma rolling. The dermarolling articles just happened to discuss vegf, and it appears that the dermaheal products can either be injected into the scalp or applied topically after dermarolling (microneedling) the scalp.

    To top off my curiousity-induced binge of posting , here is an article I came across that involved only a single injection of VEGF (sh-polypeptide 9),and a few other compounds, and claimed to have adequate results.

    http://www.des-company.com/wp-content/uploads/2014/05/Zimber-et-al-2011.pdf

      1. @22 appreciate the recommendation on joining. In the future I might do so. Since I work at an academic medical center, I have access to the best resources out there.

  12. 1 question. Everybody telling it’s a cure. But is there any side effect may arise after this treatment ? They said they will inject new follicle into the scalp. Can it make any cancer or other side effects ?

  13. So many news about new treatments, but nothing concrete about timelines or results, too confusing. Please make it happen soon!

  14. guys, your reactions are, how can I put this…hm… , pathetic?
    You talk about costs, possible SE, making it happen S.O.O.N.E.R? LOL you bunch of spoiled brats
    Be thankful for the info we have now and stop whining like a bunch of bald babies ughhhh for crying out loud
    you always react like its never enough:
    no info on potential cure = we want something in the pipeline
    something in the pipeline = we want more info and we want it sooner
    something actually might come out BY 2020 like in the f*** blog title = we want info on costs / SE / interviews / try and make our own product
    utterly ridiculous…. be thankful for being still alive while there is talks about a potential cure…
    @admin thanks for the great insight on this possible cure, and as usual, great blog, great info release, and on behalf of the bald community, I’m sorry for all these immature reponses, I guess ppl are edgy nowadays
    Now I’ll go play pokemon Go and wait for the cure to come peace!

    1. Of course we want more information. How many times have we been told a cure is just around the corner? As mjones said, the 5-10 year timeline STILL hasnt budged. My father told me that 20 years ago they were saying a cure was only 5-10 years out. Obviously those of use who are severely balding want more info. Whats the point of getting excited if it falls to the way side? We were all pumped up 6 months ago for SM thinking it was going to be great getting our hopes up. Look how that panned out. Yeah it gives 10% regrowth, but it still wont be released for a long time and by the time it is, 10% isnt going to do jack for any of us over a NW 3 or 4. So pardon our skepticism and pessimism sometimes when a company makes claims with 0 proof.

    2. Paco, yesterday I went to my local park and at least 500 people showed up for Pokemon Go. I shot a crazy short video on it.

      It seemed like 90 percent of the Pokemon players were in their 20s and not balding. I still really enjoyed my time there despite that unfortunate detail. Played for 10 mins, but then got bored and mostly watched others.

  15. Paco how long have you been balding? How long have you been on treatments ? Just curious, not going to make a smart ass answer.

    1. This blog isn’t only about finding a cure and discussing it, its about helping people cop with their situation… And I think its really important that you people realize that hair is not worth so much worrying… 21 years old speaking here…
      How about I tell you that a cure would be to change mindsets and the way people see their situation? I’m not aggressive, but posting comments like :

      “1 question. Everybody telling it’s a cure. But is there any side effect may arise after this treatment ? They said they will inject new follicle into the scalp. Can it make any cancer or other side effects ?”

      This is just stoopid sorry… Always looking for the next problem… THAT is what spoils the fun

      1. @paco, alright young grasshopper. If you worked at a hospital then such comments would be music to your ears. Such questions/comments are heard all the time by healthcare professionals.

        You have the right attitude about not letting your hair loss bother you, but unless you’ve walked in someone else’s shoes (every human being has different psychosocial issues)….

  16. 21 years old. NW7. been balding since 18-19.
    I know baldness is hard guys, but hair is hair. Stop worrying too much about it because in the end, you can’t get those years you spend worrying back…
    I’m soooooooo happy to hear about this potential cure which would, lets say it, save my youth/life, but seeing people already worry about things like side effects / costs, about something that we don’t even for sure if it will work, this pisses me off…
    Can’t you just relax and enjoy the “good news” instead of ALWAYS trying to find another issue to solve or discuss?

    grow up.

      1. I think its due to my intensive workout routine (+ protein shakes) when I look back at pictures of me in 2012-2013 (when I had just started working out) I had a full head of hair… This experience has been traumatic for me… but I also had time to realize that :
        I won’t let my happiness fade away just because of hair.
        But I would give anything to go back and get my hair back … :'(
        Its only when you loose stuff that you realize how important they are…
        (@admin sorry for my words)

  17. thats why we are humans makes us different than animals. we have brains to render unnecessary or surplus information..

    20 years ago it was all about fin… we have came to know that pills aint gonna solve ur baldness.. it has to be stem-cell research.

    so no… i really dont understand ur pessimism. and yes to your question i believe they have tested on humans and it proved to be working. otherwise they dont put out such a short commercialization timeline.

    baldness is not perceived as we were in 80s or 90s anymore. this decade is all about aesthetics. u see hollywood stars or anyone on tv? they all have 6-packs and perfect hairlines. ppl want it. things have changed from last 20 years.

    dont worry about proof I think they have it .. just not sharing with society yet

  18. paco, your a funny little dude who doesn’t know what he’s talking about…

    “guys, your reactions are, how can I put this…hm… , pathetic?
    You talk about costs, possible SE, making it happen S.O.O.N.E.R? LOL you bunch of spoiled bratsno info on potential cure = we want something in the pipeline
    something in the pipeline = we want more info and we want it sooner”

    “This blog isn’t only about finding a cure and discussing it, ”

    so are we spoiled brats or are we discussing it?

    some of us have been balding longer than you’ve been alive and we’ve heard it all and have been promised for years.

    go back to your pokemon little man

  19. No need to argue ppl! We all have different opinions bout this topic. Im glad there we’r being spoiled with so many great news. But like others have said numerous times; its just the usual we have heard so many times before. Go on every HL blog or forum and look through threads bout the 10.000 other companies whos put out news like this in the past, and you’ll see that this is just history repeating itself. Another 5 year promise from a company who has not shown any results.. yet. I really hope that these news will make some of the other companies speed up their proces so we can have a new treatment until this hits the market.

  20. @donitello
    Don’t be a wiseass yourself.
    Did you think my last comment’s sole purpose was to school someone? People are free to discuss or ask questions here, as long as the topics are related to the current post.

  21. Paco sorry to hear that you lost all your hair so quickly. I myself noticed my hair loss increase rapidly when I started lifting heavier at the gym and taking protein whey isolate. I have maintained great with Propecia for 14 years but year 12 I added whey and 6 months later crown and hairline started diffusely thinning quickly. I have been waiting since 2001 for a new treatment I can use to replace Propecia and I’m Freaking FRUSTRATED! I want some new fda treatment asap! Anything even SM, Histogen etc. 10% regrowth and maintenance will be highly appreciated. So when I hear 5 to 10 years away statements I immediately lose hope in that treatment. I honestly believe follica will bring us something good since they are setting on a 2018 release date. They took a while but most clinical treatments take 10 to 12 years to hit the market..Histogen I see being 50% chance due to all their delays same with sisheido. If they execute phase 3 and 2 this year as promised then I will bump their released success date to 75% chance. In conclusion please stop telling us to stop complaining or to live our lives. I live my life to the fullest but I should have my hair in 2016 and should have to worry about hiding from bright lights, getting hair wet or spending an hour in the morning fixing my hair with blow dryers and shit just to look normal. I want the old mjones back when I was 20 where I showed , gel up my hair and didn’t worry about hair. Every man deserved to live confident and happy

    1. You’re perfectly right and I apologize for sounding so critical about how ppl react to those leaked infos about possible treatments… honestly I think we’ll all get our hair back in a decades time don’t you think? SM follica brotzu follicum seti tsuji rivertown and now this… please tell me i’m right…

  22. people…
    the technology and science now is not the same 30,20,10 years ago.
    I understand the pesimism for wait and wait year by year. But the solutions are very very close.
    Believe me. I have 40 years old and a full head of hair. Why I read periodic this site? Because I´m fanatic of the science and the technology. I know is easy to say this for me, but the things will change soon. If you are very pesimistic, don´t read the site, is worse for you! Stay positive! Imagine good things to come!
    remember the progress of:
    cell phones
    TV
    HIV therapies
    Airplanes!
    Robotic
    sheep cloning
    in the beginning all this things are like magic, nobody trust in they but the science and technology work together to become in reality.
    this is the same… patience and optimism!
    regards (sorry for my poor english im latin! ) 🙂

    1. Well said ! Here is to the future and the increasing speed of scientific discoveries! Now is the time for not just more effective treatments, but also a full cure, and more options to getting that cure.

  23. I just hope it can be done on diffused areas with hair already on them without complication like ingrown hairs. If it can only be used on slick bald areas that would be useless for diffuse thinners.

    1. This protocol would require a transplant. The ARTAS system can transplant around existing hair – it maps the scalp and selects implantation sites that are free of hair. By the time (if) this protocol comes to fruition, ARTAS will be a fully-automated robotic hair transplant procedure, with the robot both extracting and implanting the follicle.

      That being said, any protocol that requires surgery is less than ideal to a protocol that simply reinvigorates dormant follicles.

  24. This biomemimetics stuff has turned into an itch that I can’t seem to scratch away at the moment.

    Caregen ltd. is the company in South Korea that manufactures the sh-polypeptide 9. The CEO is Yongji Chung PhD, and he was educated at Cornell and Northwestern (I’m impressed). He spoke at last years IMCAS. And this years IMCAS will be held at the end of this month in Taiwan!

    http://www.imcas.com/en/attend/imcas-asia-2016

  25. Hopefully we will all live to see this day, NATO USA and russia are getting very heated and threatening nuclear warfare

  26. I think this hair cloning is the best we are going to get seems like if there was a way they could just give us some special water and make our original hair follicles grow again like a Chia pet they wouldn’t have gone this route.

    1. Yes I agree. Why did Tsuji go straight to wanting to recreate new follicles? Because he is a clever man who understands that reviving ‘dead’ follicles is more complex than creating new ones! George Cotsarelis seems to be of the same mind.

      I think with shiseido, samumed and brotzu lotion we will get the full extent of follicle revival potential for a generation. The major “cure” for our generation lies in hair cloning.

  27. guys this century is all about well being. This was not the case 30 20 years ago. turn on tv first thing u notice is 6-pack guys with full head of hair. unfortunately being ugly or bald is not appreciated by society anymore.
    thats why prince williams , rooney ..etc are all desperate for their hair. if u r on tv, u have to be beautiful…
    in 80s 90s, social media wasnt there so baldness werent big deal. right now we all have super zoom camera and constantly scanning if ur hair is falling out.
    like i said so many discontent people out here and shouting for the cure.

    I have asked Admin million times to actually post an article to show how much attention baldness cure gets. I am pretty sure the numbers will highly surprise you because it is HUGE. it gets alot of attention and money.. investors are fully aware of the potential…. whomever finds it first, seriously gets the holy grail.

  28. Guys I have diffuse thinning with two empty strikes on both sides of the head.

    I am on fin for 4 months but no regrowth and I am dissatisfied by the appearance of the white lines on the sides and back of the head.

    I do not want to use minoxidil, I only want to use brotzu lotion if it is released.

    However, would it be an idea to use minoxidil on my white lines for 6-12 months or however long it takes for brotzu’s lotion to hopefully be released? If for some reason it is not released I have no intention of continuing with minox.

    Would minox keep my hair/regrowth healthier while waiting for brotzu, or could it make things worse?

    Thanks

  29. Minoxidil gave me horrible side effects, bloated face, high bp, edema, dark circles etc. When i quit after 2 months of usage i Lost 60% of my density and 10 months later it never came back…

  30. Habe..I’ve been on Rogaine for 20 months. It really has done much but thin my hair where I applied it and it’s destroying my hair line. The weird thing is it did grow hair back on other diffuse parts of my scalp and made my hair grow straighter and healthier. However I’m worse off today than when I started. It’s very weird cuz it works in some parts but not on others

  31. Guys I’m not so sure Dr. Tsuji knows what we need. He is a man with a thick, full head of hair.

    I fear that he believes our trouble is slick bald areas. His plan seems to be to treat slick bald areas on the top of the head only. Like this:

    https://www.hairlosstalk.com/interact/proxy.php?image=http%3A%2F%2F3b1rei1g80li17gzklst5pgc.wpengine.netdna-cdn.com%2Fwp-content%2Fuploads%2F2015%2F07%2Fhair-growing.png&hash=727a72673896295573c94b5071b7275c

    When what needs to be on offer is this:

    https://www.hairlosstalk.com/interact/proxy.php?image=https%3A%2F%2Fs31.postimg.org%2Ffujogrezf%2Fhair_growing.jpg&hash=7eb9e232299e81aded97b9b7a867491f

    We should let him know in a group email what we the consumers require. That is a treatment where enough cell germs are created to regenerate new follicles on every last cm of head (the top, the sides, the back, the nape).

    This is important because in the next few years they will likely settle on a protocol which will be the basis of clinical trials and will be difficult to change in future.

    Treating the whole scalp should be entirely possible but it needs to be worked into their plans at this stage to account for the additional cells necessary etc.

    Maybe then there could be two treatment options available: whole scalp procedure or part scalp procedure.

    1. W.t.f…beggers cant be choosers, and people complain about something potentially amazing. Also dont think you understand what he is actually doing…

  32. Can someone please tell me why so many are so excited about brotzu? I want to get excited too, believe me, but why? Has there been a bunch of proof such as pics that I didnt see???

  33. mjones do you recall when SAM started phase 2? that was really fast. if they keep that up it could be phase 3 by 2017

    So what are all the competing companies now? Histogen, Follica, Shiseido, JAK, Riken, and now SAM are all on the table?

    1. Egg head yeah samumed was getting phase 2 done quite quick. I hope they start phase 3 before 2017. Hopefully by late fall. I will love to have a new topical that could halt hair loss and grow back 10% in 3 months. I know it’s not a lot but at this point anything is better than watching my hair thin out each day. Histogen is to start phase 3 this month, sisheido sometime this year. Yeah the ones you listed are the competing companies plus Follicum, Riverside Pharmaceutical and even Latisse is still in the game. I remember the ceo of allergan stating that he would release Latisse for baldness in 2019. From the looks of it they are back at stage 1 so it probably accurate timeline. They completed phase 2 with crap results. Maybe they can complete phase 1 and skip to 3 if they see much better regrowth.

    1. Thanks egghead! I have had such an idea in mind for a while and have been told to do so a few times…might just happen when I have a less busy week on my hands and can search for appropriate plugins and so on.

      1. sweet! =]
        ya lotta newbies need clarification and for the older visitors, a meter might provide a psychological milestone

  34. I feel like Follica is a backup to Riken lab in case Tsuji runs into trouble with multiplying cells.

    Even though Follica have set an earlier possible release date of 2018, that won’t be a cure.

    Doctor Cots himself had said that a cure-like treatment from Follica would take many more years (possibly 10, 15+ years. maybe with the use of fgf9).

    Trouble with Cots is he works damn slow. He was in the hair game in 1990 when Tsuji was working for a freaking tobacco company lol.

    Tsuji has only been in the regeneration game 10 yrs and has arguably accomplished way more solid results and has grander plans of regenerating all kinds of organs besides hair.

    If the US is not conducive to research, might I suggest to Cotts that he relocates to the Bahamas, maybe enter partnership with thorn medical.

  35. Hi does anyone have any tips to stop the creepy crawling feeling on my scalp. It actually wakes me up at night and my hairloss has been super aggressive lately. I cant tolerate fin or minox or nizoral fyi. Im really down guys. Life isnt fun right now.

    1. Hi tom i used potassium permanganate to wash hair. It stopped itch and any other odd feeling on scalp. Just added very little powder in water bucket and used any shampoo with it. Water will go dark pink. Just do it 3 times a week. Two weeks like that and its gone. Also coconut oil massage at night, even once a week massage will help. Potassim permanganate is very well known compound. Search for potassium permanganate bath in google.
      Hope this helps u!

    2. hope you get this, I had that feeling for 10 years, use tea tree oil once a week, apple cider vinegar-garlic-onion in a blender. Sounds wierd – totally works, I totally forgot what that sensation feels like. I’m pretty sure you have a fungus/demodex under your epidermis, almost 100% positive that’s what that is

    3. @TOM This is not a diagnosis/prescription, but you might want to try adding 5-10 drops of NOW tea tree essential oil into 1-2 tablespoons of liquified coconut oil, massage that into your scalp, and leave in for 30 minutes, then wash out (and stop using hot water to wash your hair!)

  36. I’m brand new to this forum. I started thinning at 21 and was NW4-5 by 24, which I have been since (now 30).

    It’s nice to see news like this, but after having my looks and life ruined, I don’t hold out much hope. Even if there is a cure, because of my confidence being wrecked, I have a low end management job just 2 rungs up from bottom feeder lowest entry rung, and probably could not afford the treatment anyway.

    Not only that, but shaving my head regularly for the last 5 years has left me accruing quite a few scars from nasty cuts, so I doubt any new hair can grow through the few small scarred spots – though this is nitpicking.

    On top of all this, even if there is a magic cure in 5-10 years, I’ll be 35-40. What’s the point? My youth and life have been ravaged, and regaining my confidence would be pointless to a 40 year old, who would be too late to start a professional career and life.

    Glad you’re all optimistic though and for the young ones I wish you the best.

    Maybe my generation will be able to enjoy the radical life extension and reverse aging technologies of the future so I can have my 20’s back that were utterly robbed from me by this awful affliction.

    1. That is tough, but perhaps you can focus on yourself physically and mentally like others do. I’m between a NW2-3 i think, slowing receeding since 18.. I’ve been a little bit of a gym bunny during my time and there is honestly so much confidence from just being in shape.

      There are bald people, NW4-6 with their hair still out but they don’t care because they’re in shape. I think thats really key, i am hanging onto my hair a little longer but i’ve realised how time consuming maintenance is.. reading this website is.. waiting for a cure is..

      Before your youth passes just enjoy it, live life. There are actually women out there like bald men and that a mans hairline isn’t the only desirable thing.

    2. You ought not to think that way.
      I strongly believe the best years a man can have are actually his 30s and 40s.
      In the relationships’ department, I think it’s gonna be just fine. Twenty-something girls are way more attracted to the thirty-and-forty-year-old guys than you think. That’s also true for many young gay guys, like me.
      Besides, shaved heads are appealing to some.
      I would very easily give my male vagina to guys like Pitbull, Vin Diesel, Pepe Guardiola, Gustaf Skarsgard and so many other bald and balding guys.

      Profession-wise, starting all fresh at your forties is a bit harder, sure, but it’s not infeasible to be successful. You just need determination and drive.

      All in all, it’s not the end of the world, man.
      Be strong.
      Take a good care.

  37. hey guys, quick question here:

    Thorn Medical plans to release its treatment for the end of this year… isn’t that just huge/great/amazing/????
    From what I heard/read: “we can provide a cure for baldness”… they seem to have the solution right?

    Why aren’t you guys so happy about that? Is there something fishy?

    thanks

  38. Just some of my thoughts:

    –I think it’s important to understand that this isn’t a sure bet.

    The good (great) news: Tsuji’s work before showed if they can get the amplification working, it should most likely work on humans. Baldness would be treatable unlike anything we’ve seen before. Really cool stuff if you ask me.
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337983/

    The bad news: Tsuji’s work didn’t *amplify* the dermal papilla cells (get millions of DP cells from just a few), if i’m understanding it all correctly (please correct me if I’m wrong).
    http://stemcelltherapyreviewjournal.com/dr-takashi-tsujis-stem-cell-cure-for-baldness/4/

    Going to get a bit technical:
    This is actually a big issue, and NO scientist has been able to get it quite right. See, when you multiply the DP cells in culture, they lose their ability to regrow hair for some reason. Scientists been able to delay the dermal papilla’s loss of trichogenic (hair making) ability in culture/in vitro, but not eliminate it entirely.
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221925/#bibr15-2041731414556850

    That being said, DP cells lose their trichogenic ability when left *alone*, I have no idea if Tsuji’s method of combining the DP cells with the epithelial cells will be able to get around this hurdle, as there’s been no published work. (Also there hasn’t been much mention of the 3D culturing in my reading)

    However, it sounds like Tsuji’s run into the same issue. This is from Swoop’s comment on HLT regarding Tsuji: “[Tsuji] mentioned the problems at the moment are the expansion of the epithelial bulge stem cells and DPC. He said the critical issue revolves around expansion of the epithelial bulge stem cells though.” Maybe I’m reading into it too much, but I read ‘expansion’ as ‘amplification’ here (perhaps a language gap, because expansion doesn’t make sense to me, but again please correct me if I’m wrong anyone). I find a bit of reassurance in the fact he says that the expansion of the DP cells is not the critical issue, it’s the epithelial cells that are the problem.

    But nonetheless, there are still some BIG hurdles that no one in the field has been able to get over. (In my opinion, if someone is able to figure this out, THAT’s the cure for baldness) Thus, this is why it’s still in Research & Development.

    On the other hand, RIKEN’s post on their website said: “establish cell culturing and transplantation *techniques*”. Maybe this mean’s it’s already been done, and their just working on the best way to do it? Hopefully, but I think my reading here is a bit of a stretch.

    That all being said, this is great news. At least Tsuji, one of the most knowledgable guys in the hair regeneration field, is working on a treatment with a big developer. Hopefully something comes of it. Just as well, I think Tsuji would be the man to get over the DP cell issue I mentioned above. Further, his research has been out there for 4 years now. Hopefully he’s learned a thing or two since then.

    That all being said, if anyone has contacted Tsuji since March, I’d be really interested in any new info. I might reach out soon if not.

    Your’s hopefully,

    Booyeah

  39. @Paco, where did you hear this?? Thorn will release their product by the end of the year? Sounds awesome but what about trials and so forth?

  40. I just don’t get all this fuss.
    Effective hair cloning merely means that HT surgeons could potentially implant as many grafts as they would be needed to cover all bare spots without extraction . Normal densities wouldn’t be achieved whatsoever. Failures would not be ruled out, to boot.
    To make matters worse, the trials are to be completed in the early 2020s (if there are satisfactory results, of course) and some additional time would be needed for the surgeons to get a good grip.
    With all that said, it’s gonna be 2025, even 2030 that we, the baldsies are gonna get some improvement to our problema and by no means THE CURE we all yearn for.
    Personally, I believe the cure is going to be achieved through gene therapy or hormonal blocking (more advanced to terrible finasterida) and that ain’t gonna happen at least the next twenty years.
    I’m not being pessimistic, guys. I’m being realistic.
    Don’t nasty-comment at me, por favor.

      1. You’ re probably right.
        I read transplant in the articles and got the wrong idea.
        It’s not hair cloning.
        It’s transplantation of laboratory-cultivated cells.
        With that in regard, I’m starting to fear that 2030 could be a rather optimistic timeline.
        That’s way worse.
        Καλή μας τύχη!!!

  41. Can’t help but to smile at that updated picture. And sets email response.

    “Regarding timeline, we aim to put the technologies into practical use and make medical treatment available in 2020 in Japan (medical treatment at one’s own expense).”

    Hey everyone saying “don’t get happy about this” – SHUT DOWN, EAT THE SHAM BURGER.

  42. exactly Egghead. All of a sudden people here became smartass scientist and giving their TIMELINE rather than what Dr Tsuji aka the guru of stemcell research.

    On what ground u can give 2025 or 2030 timeline? Do you even know Dr Tsuji? yes the one u see on the photo…

    People who did nothing more than cutting a frog in their science class is now putting their timeline opinions.. yeah this is internet!!!
    just face palm.. but dont worry next thing they do is to create a time machine just for you so that u can go back in time and delete this post of yours.
    expand ur horizon and dont be smartass and challenge Dr Tsuji.. idiot…

    1. 2020 ain’t gonna be the year humankind cures hair loss. Even if everything works out just perfecto and the final product is released in 2020, by no means is it gonna be the cure.
      Do you know what cure stands for?
      Hair transplants ain’t the cure. All they do is hide the problem, don’t they? (I’m fine with disguise as long as the result looks natural and descent density-wise, don’t get me wrong on that)
      If I’m wrong with the timeline I gave and the hair cloning comes earlier, I’ll be thrilled.
      If I’m right and it’s available in 2025, you’ll be devastated.
      With both scenarios I’m happy. You’re happy with the 2020 scenario.
      Who’s the idiot now?
      Eat you burger. It’s delizioso,

  43. Guys, we potentially have hair cloning in the works, okay it’s not as natural but it will still be close enough. Please remember that if you want a full natural look nature wants you to be bald… We are getting closer and you still see no light and complain! Can’t understand…

  44. Yes we are getting closer. And of course all companies are moving quickly and working very hard for a new treatment…well all companies…no…SOME MORE THAN OTHERS…. 🙂

  45. Is follica going to meet that 120hair /cm2 they annonced ?? Not sure but it would be perfect though. Being able to grow 120 density

  46. I would be surprised and would be good if they did that. I believe it more on hair cloning , since we can achieve that now with hair transplants but has we know limited hair supply.

  47. If our hair cells die out after some time then rejuvenation would still give us diffuse hair wouldnt it so cloning is really the only way right?

  48. Admin, Great blog and my #1 choice in staying up to date with new developments. I was wondering if you could devote a post to the latest developments in cell culturing and the success rate regrading the % of the retention of gene expression of DP and/or DSC cells when cultured. It would seem that this is really the key that would break this avenue of treatment wide open. The best discussion I have seen on this was here in 2014 with Dr. Aaron Gardener: https://www.baldtruthtalk.com/threads/16284-Q-A-with-Dr.-Aaron-Gardner
    The string went dead about 2 years ago but at the time Dr. Gardner reported that with his research, the maximum % of induction that had been attained in DP cells was 40% (see page 8) with 0% in DS cells used in the Replicel method (see page 11).

  49. Not really getting the skepticism/pessimism here in the comments. I think a lot of people are waiting on that magical topical ointment or “hair cloning” cure. Well guys…the science has demonstrated that neither of those are really feasible. It is obvious at this point that a cell-based therapy is the only solution and that is EXACTLY what Dr. Tsuji has. His method has been shown to regrow follicles in lab animals and RepliCell/Shiseido’s phase 1 trials showed that it is possible to rejuvenate thinning hair. The WORST case scenario here is that you may have to get both Replicel and The Primordium method.

    You have a trinity of some of the biggest companies in electronics and regenerative medicine putting more money than ever before into building an automated facility using the most supported, best research in the field and the Dr. behind it is at the helm. These people are not snake-oil salesman of old, they are leading scientists and innovators, they would not spend this kind of money, resources and staff on something they have no good reason to believe will work. So I’m sorry, but I’m inclined to believe THEM on their timeline.

    We have a handful of companies with research showing that it is possible to regrow follicles and rejuvenate dying ones via stem cell therapy and injections and they are now putting commercial treatment into motion.

    If this isn’t a “cure”, then nothing ever could be.

  50. Biggest and most exciting piece of news so far. Whether or not they’ll actually have it by 2020 is definitely debatable, but this IS the cure.

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