If Shiseido Decides to Do So

Update: November 26, 2019

Shiseido Japanese Patent Published

Someone named “Paul” (thanks!) just posted a link to Shiseido’s official Japanese patent, which was released in Japan in May 2019. Paul found this link on an investing forum, and he also posted a bunch of information about stock prices. I deleted the latter, as I do not want to encourage blog readers to buy or sell Shiseido or Replicel stock.

Ultimately, whether “Shiseido decides to do so OR not to do so” will decide everything. The patent indicates optimism about the technology. However, nothing is set in stone for sure. The English translation of the patent is extremely informative if you expand each section and wait for it to load. Or you can open the whole Japanese pdf too and use translation software.

The big question I have is what portion of the technology comes from Replicel (licensing), versus from Shiseido in-house?

The inventors are listed as:

  • Tsutomu Soma
  • Jiro Kishimoto
  • Sayaka Koide
  • Hitoshi Okochi
  • Masahiro Kiso

Update: November 26, 2019

Replicel Year-End 2019 Update

RepliCel released its 2019 year-end update today. It includes discussion about its partnership with Shiseido. Regarding Replicel’s cellular therapy (RCH-01) for androgenetic alopecia, the key points are that:

  • Shiseido’s clinical study in Japan is now complete.
  • Shiseido will soon announce on whether it will commercially launch the product in Japan or conduct further clinical testing.
  • Replicel is holding off on Shiseido’s final decision before pursuing any further Phase 2 trials. The former’s Phase 1 trials in Europe were successful.
  • The Replicel and Shiseido dispute is still unresolved.

It seems like Shiseido could still launch the product in Japan soon. No doubt aided by the country’s new faster regulations for marketing when it comes to cellular therapy.

Replicel’s proprietary injection device, RCI-02, is on schedule to get approval and be used in much of the developed world in 2020.

Replicel-Shiseido Partnership

March 23, 2019

I used to cover Replicel (Canada) and its Japanese cosmetics behemoth partner Shiseido at least a few times per year until last year. At some point, I got skeptical about the RCH-01 autologous cell therapy hair loss product being released any time in the near future.

Shiseido LogoBesides typical delays, Replicel and Shiseido had some unclear conflicts regarding their partnership.

However, Replicel published two important updates this month, the second of which is of most interest to us:

Per the first link above, the disagreement regarding the agreement between Shiseido and Replicel remains unresolved. However, it is not subject to any litigation or arbitration at this time.

The key money quote is from the second link:

“While the Company’s RCH-01 product for hair loss due to androgenic alopecia may be launched in Japan much earlier if Shiseido decides to do so, current planning anticipates the potential for all four products to be on the market in Japan by 2022.”

The implication seems to be that:

  1. Shiseido could release the product well before 2022. See my past post on the company’s new research facility in Kobe, Japan.
  2. Even if Shiseido does not release the product earlier, it will quite possibly get released in 2022 in Japan by Replicel.

See my past post on Japan’s new laws fast-tracking stem cell therapies and clinical trials.

Another key quote:

“Unlike anywhere else in the world, one well-designed cell therapy trial in Japan, approved by their regulatory authorities, has the potential to lead to product market launch.”

Replicel is clearly focusing on a “First-in-Japan” strategy due the country’s favorable regulatory environment. Shiseido has rights to the Asian market when it comes to RCH-01. However, it seems like Replicel can still release the product in Japan in 2022 if Shiseido does not do so?

Hard to make this conclusion for certain without knowing much more about the two companies’ legal contract. In any case, this is a great development.

Further references:

— A discussion of Replicel’s technology in two videos.

— Shseido and Adenosine for hair loss.

87 thoughts on “If Shiseido Decides to Do So”

  1. Interesting, but if Shiseido chooses not to release it prior to Replicel (2022) wouldn’t one assume it’s not very effective ?
    If it’s a home run or even a significant improvement over what we have now , Shiseido would make a killing and would want to cash in right away prior to other companies in the industry also working on similar solutions .
    Something doesn’t add up !

  2. Shiseido is a cosmetic company. They’re in the business of selling something you need to use again and again every day. Replicel is marketing an injection process that improves your hair, not something you can do at home indefinitely for a moderate cost. That seems to be the disconnect. Shiseido wanted to see if they could somehow turn the injections into an every-day topical and just couldn’t get the same results and are therefore now less enthused. It doesn’t match their business plan. Hopefully Shiseido can release the injection plan at some point.

    1. Where did you you get your information that Shiseido was trying to turn this into an everyday topical? I tend to agree with Stu. Their premise has been based on culturing cells and no group has figured that out yet, let alone an under-capitalized company like Replicel. I also recall some time ago where a researcher, who was involved in cell culturing, was posting on a site saying that while there had been some success with culturing dermal papillae cells (up to 60% inductivity), there was zero success in culturing dermal sheath cup cells, which is what Replicel is based on. Maybe this has changed, but if you look at Replicel’s stock it is at an all-time low of under 20 cents per share. So if they have had any behind the scenes success, they are very tight lipped about it.

  3. One important side note left out in this article is we know for sure shiseido started human trials over a year and a few months ago.

    That being said despite our shaky speculation we know for absolute certain that there are people deep in that company that know for sure whether it works or not right now .. Today.

    My only wonder is Why they havent gone public. If it worked wouldnt they already have organized preliminary treatment centers. It makes me doubt success.

    The only way it does work is if they are in the marketing process right now. But they said 2018 so….. If they stalled on that release they either scrapped it or tweaking the delivery for a higher outcome. Or it doesnt work at all.

  4. Incuded in Replicel’s agreement with Shiseido was a commitment to complete their own Phase 2 trials of RCH-01 in Germany.

    When Replicel failed to conduct these trials, Shiseido claimed the terms of their agreement had been broken – and as such Shiseido would no longer share either the results of their trials, or any future revenues, with Replicel.

    Replicel disputed this by saying the agreement didn’t stipulate “when” they would conduct the German trials, just that they would.

    This is why Replicel now essentially doesn’t know more than anyone else about where Shiseido is at.

    In the meantime…..Replicel has been involved in a joint research project with the University of British Columbia seeking to clarify what differences existed in the hair follicle gene expression of subjects who had a strong hair growth response in their earlier RCH-01 phase I/IIa clinical trials and the subjects who had a reduced hair growth response.
    (The recent Replicel shareholder update stated stage 1 of this research “has successfully completed (details to be announced shortly)”)

    Presumably if Replicel can isolate what particular gene / protein expressions yield better treatment responses for their treatment, this might bring Shiseido back to the table – as otherwise Shiseido would be limited to using only the earlier Replicel technology covered in their original agreement.

    So it will be interesting to see both the results from the University of British Columbia joint study and the Shiseido study when they are announced – and how this may all play out.

    1. This basically answers the question you posed in the following post. Investors see an argument with one of the largest companies in Japan and run a mile. Any reasonable analysis of the information publicly available shows Replicel are at fault for not holding up their end of the bargain. This is a poorly run company with a decent-ish product. Without Shisheido’s backing i have lost all hope for this product.

  5. They should just release whatever they have, even if it’s just maintenance. Too much bs with hair loss industry. Why does everything have to be so exhausting with this sh*t.

  6. They have every incentive to meet their 2022 target, otherwise they won’t be first in Japan. Riken comes to mind.
    I suspect this year will be make or break for Replicel’s RCH-01 depending upon the results.

  7. I live in Vancouver where the University of British Columbia is – there were no human trials at UBC , so I’m curious where all this talk is coming from ?
    They ( Replicel’) did do a trial a few years back on Achilles’ tendons and I actually tried to get in but didn’t qualify . At the time , I spoke with someone who was overseeing it and was at an arms length distance from Replicel . He was involved in making sure their trials were ethical and run propey .
    I questioned him and he was somewhat open about Replicels technology, to me he didn’t seeemed convinced it was sound for both hair and the Achilles .
    Put it this way – he had already seeem preliminary results and he was not all That excited . Ever since that conversation, I’ve never been convinced Replicells science is the answer,
    Im guessing , it does something, but for myself , it probably wont be a game changer .

    1. Hi Stu,

      I have no “inside information” – the reference for the UBC study came from a Replicel news release, June 13, 2017. (See link below)

      I believe the study intended to use pre-existing data from Replicle’s earlier trials rather than conducting new human trials.

      Was interesting to hear the views of your friend / associate who was somewhat involved in the Replicel tendon study!

      Cheers.

      https://replicel.com/news/replicel-collaborates-with-university-of-british-columbia-to-build-world-class-hair-follicle-cell-data-map

    1. Hey Bekoo, you’ve posted the link twice which makes it a broken link.

      https:/edgy.app/researchers-discover-new-hair-loss-prevention-technique

  8. Yep great work Xtra and all other comments -been waiting for this post admin ..:and will be eagerly waiting for more as I think this regent stuff is the cure!

    1. FYI, George is a speaker next month at the 11th world hair congress, maybe some news. Also Samumed is one of the main sponsors.

  9. I think the “If Shiseido decides to do so” comment was just them not wanting to speak for Shiseido.

    They have a history of playing it close to the vest and not overhyping, which I actually respect

    1. That Rapunzel site sounds promising. The same idea behind Tsuji is it not? Does Christiano have cultured hair cell science up to where it needs to be to start performing the so called “cure” of unlimited donor area hair transplants?

  10. Hi Admin,

    What’s your take on this HairClone (UK) Reddit AMA?

    https://www.reddit.com/r/tressless/comments/a65uew/hairclone_developing_cell_replacement_treatments/

    Although I highly appreciate their CEO taking the time to answer questions, I find it an absolute joke they have the audacity to tell people to crowdfund them with no proof of concept. Another thing is the involvement of a certain hair transplant doctor tells me this is nothing but a marketing exercise for his UK clinics.

  11. Hey guys has anybody used rogaine? What are your experiences with it? My hair just started thinning should I wait to use it? How is the dropper or foam? Which is better?

    1. I use the Regain foam and have found it has slowed my hairloss over the last 4 years. You have to be consistent with it. It’s not a miracle and i’m still losing ground but definitely at a slower pace.

    2. I used it for 9 year, but stopped giving benefits the last few years. My heartbeat increased to the point that I had to stop. At that point i had a massive horrible shedding and thing kept going downhill. My advice is don’t even start that crap.

  12. A couple weeks ago there was a really, really good article about Christiano: https://magazine.columbia.edu/article/radical-solutions-baldness

    Some Quotes:

    “She quickly learned why there was so little progress on hair disorders. ‘Institutions wrote back to me saying, in essence, that hair loss was trivial, cosmetic, insignificant in comparison to AIDS and cancer.”

    It had been fifteen long years since Christiano discovered the first gene for hair loss. […] “I’m happy to say that this year, for the first time, we’ve finally found some genes.” The room got quiet. Then people stood up. They began to weep, and, in a show of unity, they started taking off their head coverings. Christiano, unprepared for any of it, dissolved into tears.

    Christiano learned more about the feelings that surround hair loss. “Because the condition is usually progressive, once it starts, people really struggle,” she says. “I’ve heard people say: ‘I couldn’t get out of bed.’ ‘I will not take off my hat.’ ‘I won’t go out in the wind because I’m afraid my prosthetic will come off.’ ‘I won’t be intimate with someone.’ ‘I can’t go on this job interview.’ ‘I’m afraid to show my family.’

    “You need to walk a day in the shoes of someone before you cavalierly dismiss AA as ‘just cosmetic.’ It’s easy to trivialize it. But people are desperate, and vulnerable to the core. They’re up all night reading about hair and counting the hairs in the drain and looking in the mirror. You can’t understand it unless you’ve been there.”

    [of JAK Inhibitors for AA] The drugs are still in clinical trials and could gain FDA approval as soon as 2021.

    There has never been a truly successful treatment for the most common form of hair loss, androgenetic alopecia, better known as male pattern baldness.

    FROM ONE, MANY

    “Experiments are underway, and the evidence has been tantalizing. In theory, that little scallop of scalp floating in the dish at the Christiano Lab could be the source of a full head of hair. Working toward that future, Christiano and her team harvest the cultured follicles and implant them in artificial skin built in the lab. This skin nourishes the follicle, prodding from it a colorless, keratin-protein filament. The team then removes the productive follicle and grafts it onto the skin of a mouse. The result? Hair growing out of mice — human hair.

    Christiano expects to move these trials from mice to people in two to three years [2021-22], bringing nearer the day when people can grow, in a lab, their own viable hair follicles — a limitless supply of one’s own hair.

    “From one, many,” Christiano says. “That’s a beautiful technology.”

    [!!!]

    1. Don’t worry guys, the cure is only 5 years away.

      2024: Don’t worry guys, the cure is only 5 years away.

      2029: Don’t worry guys, the cure is only 5 years away.

  13. I seem to recall a posting from Replicel that Shiseido was waiting for Replicel’s dermal injector to hit the market first before proceeding with bringing the hair loss “cure” to marketplace. If that is still true, Replicel announced today that the injector will be released next year in China, Hong Kong and Europe.

  14. Results from Shiseido’s study of RCH-01 in Japan will be released within two months (as of posting) as per personal email from Dr. Tsuboi, who lead the research. No word on market launch or effectiveness however Shiseido recently redesigned the R&D section of their website and it includes the Cell Processing and Expansion Centre (SPEC) in Kobe front and centre on a map:

    https://www.shiseidogroup.com/rd/collaboration/

    In my opinion, if it was a dud, this would have been quietly removed. The fact it is there makes me optimistic.

  15. If RHC-01 was really promising, Replicel’s stock wouldn’t be at .25. And they’d have no trouble getting more funding. :(

  16. Guys better wake up and I say this with a heavy heart. Unless you get hair replacements like Scott or hair transplants, there will not be a cure for baldness. In 2020 do not expect a cure and truly that is sad.

  17. The below link has been shared on a stock forum. I have included what the guy posting it has put as well. Can a cleverer person than me explain this?

    https://www.j-platpat.inpit.go.jp/c1800/PU/JP-2019-058164/60AB88FAF5C4DAC7C46914179D50FFAF571630E1250B4FCEE674882A08D3B041/11/en

    Admin: Sorry, I had to delete much of this comment as I do not want people to buy or sell stocks based on some pre-existing patent. No guarantees that they will come out with this product, even if they saw success in mice and humans. A few other companies have shown such optimism in the past, only to fold or keep delaying for years and years. I guess that even by writing these comments I may be influencing people one way or the other. So my final thought is that just always be wary and make your own rational decisions.

      1. I did not take it as such, and thanks again:-)

        I have been following the hair loss world for what must be close to 20 years now. Disappointments galore despite patents promising heaven.

        1. Agreed, you do great work though I’d have never heard of half the possible solutions on the horizon if it wasn’t for this site, fingers crossed one pays off soon

  18. Since when did it become cool to be Eeyore?

    This is good news. Hair loss is one of the most complex medical conditions, certainly among the common ones, that humans deal with. We have gone from terrible looking transplants in the 1950s to a potential cure a few years away at most and maybe even sooner.

    If you aren’t satisfied with the pace of progress, why are you on this forum and not in a lab developing a cure yourself?

  19. Now that we are almost in 2020, I’m wondering which potential treatment / cure is most promising. What do you think, guys? Admin?

    1. I’m going to come out of left field and say that, for results now without waiting for newfangled technology, Botox injections into the scalp. I read the materials at perfecthairhealth.com and the basic idea is that mechanical stress to the scalp causes fibrosis around hair roots which causes miniaturization. There are plenty of studies involving Botox that validate its effectiveness and a number of site members have used a scalp massage technique that loosens the muscles.

      Mind you, if you want to actually get your hair back, you’ll need to supplement mechanical relaxation with wounding or PRP. But I am going to be trying the Botox approach. I will report back any results as they happen.

  20. My thoughts are that if they really had something here there would be urgency to get it out. Delays have always amounted to nothing in the past.

  21. If an affordable cure comes out in the first half of the 2020s then I guess we would be hitting jackpot.
    The chances of it being released in 2020 are pretty much null. But nonetheless the admin should keep up the great job that he has done thus far.

  22. Shiseido is the cosmetics equivalent of IBM. The wheels turn slow, but they do turn. My hope is they have cracked it and the delay is for legal/red-tape reasons.
    The recent “photo proof” by Aclaris and Follica clearly tells them there is no rush.

  23. Wanted to give a shout out to all my brothers and sisters today that are meeting up with families or friends or whoever and will feel obligated to try extra hard to do something with any hair they have left to try and not stick out like a sore thumb. I wont be eating with anyone but there are many on here that will feel your pain. However enjoy the food and try and relax!:)

  24. Quick Bit on Minoxidil:

    Guinter Kahn, a balding man himself, discovered the effectiveness of minoxidil as a hair treatment in 1971, but couldn’t take it because he was allergic to it.

    Minoxidil, at the time, was owned by a company named Upjohn. When they were informed by Kahn about the hair growing potential, they reported Kahn to the FDA for conducting unauthorized experiments, then secretly filed a patent for Minoxidil as a hairloss treatment and sat on it. Rogaine was finally FDA approved in 1988 for hairloss.

    In ’89 it was deemed a spectacular failure. Snake oil hair loss remedies were outselling Rogaine 10-to-1. [Upjohn] believe the blame is on consumer’s expectations being too high: they warned from the start that the tonic wouldn’t work at all for most men.

    Tragic irony, corruption, and deception. At my most cynical, it sure seems like the hairloss industry hasn’t moved beyond the snake oil salesmen, only the language has changed from the ‘super miraculous see-it-for-yourself’ theatrics to stoic presentations in webcast graphs and biotech buzzwords.

  25. Hi Tocatta, I’ve been saying this since day one on this site and I always get back lash for saying a cure will never be released. Look they knew minox worked since 1971 and didn’t release till 1988. Wtf. They have probably have much better working treatments that are just sitting in some lab. We will only get treatments like follica, fin, cb, prp etc that just gives you slight growth. If you want more hair get fue. They will never release a product that will outperform an ht. Ht docs will be the ones to perform cloning if ever released. So all these new drugs in the pipeline are maintenance and slight regrowth. Imagine if follica could grow your hair back to me status. Who would go get an ht done and get all cut up, hide for 2 months during healing and spend 20k. Nobody. The industry won’t allow a treatment to outperform ht. The next day ht clinics would shut down. It’s all about money! I know I have turned sides on follica, but I wouldn’t be surprised if they could turn a nw6 to a nw1. Maybe they have done it but will only release a treatment that works 3x better than minox. Then in 10 years they release the new compounds that will work 3x better than follica 1.0.

    1. You don’t get back lash for believing a cure will never be released. It’s a valid viewpoint. Like the scientists of the 1800s that tried to turn copper into gold, it might not even be possible, in any amount of time. They have tried since ancient Egyptian times 5,000 years ago. If all it took was a bit of raw seeds, onions or micro-needling you would think they would have figured it out by now.

      The reason you get back lash is you believe in all that illuminati/conspiracy rubbish that in secret there is a cure to hair loss and probably cancer as well but the evil rich suited men won’t let you have it. They are also apparently deliberately injecting autism into children and turning the frogs gay.

      May I suggest the Alex Jones channel.

  26. Scott don’t be naive my friend lol. If you think they cant cure cancer or hair loss then you are living in the clouds. They can grow vaginas, kidneys and bladders and have actually implanted them into humans. You are telling me they cant grow or 3d print a follicle?? Come on dude just stop. THEY CAN! They won’t release it because we are all desperate and the rest of the millions of other people who will use cheap snake oils and big three will huy this stuff. They make billions just like the weight loss industry. It’s the same desperation. You cure weight loss there goes a billion dollar industry. All we will get are mediocre treatments that will give us short term or weak results to keep us somewhat content. People get excited for 5 new hair strands lol. Industry feeds off this desperation and profits like crazy. Why release an expensive cure for only few to afford one time and be done when they can release follica, prp, min, cb, sm, to millions for their whole lives and make billions. As you always say follow the money….

    1. Don’t agree with the HairLoss conspiracy and I believe many conspiracy theories due how corrupt the major gobs clearly are. However, everyone is afflicted by baldness even Donald Trump. If he could print hairs he would. This is however why I think there will be a fix cure (3D printing or multiplication) before a magic pill or potion that truly effectively Prevent hair from falling out. There’s so much more money to be made from a patch cure than from propecia etc. Ps the government killed Princess Di. :)

  27. Jesus Christ, is this a hair loss site or a conspiracy forum? Hey, let’s talk about how the oil industry is suppressing a small device that can make your car get 100 mpg while we’re at it. I can only assume if you are claiming this paranoid nonsense that you don’t actually have hair loss and are just trolling the more gullible members of this forum so they despair. Well, bravo.

  28. This isn’t a hair loss site anymore because there isn’t anything new coming out worthwhile lol. We have to argue about conspiracy theories to keep ourselves entertained haha. It’s going to be awhile before a real regrowth hits the market…2030+.

    As for the oil industry they definitely have a huge hand in lobbying to meet high mpg engines on the market . That’s not a conspiracy theory it’s well known lol. I went to bmw factory in Germany and spoke with a lead engineer there who developed a 85mpg inline 6 engine for their 3 series. They said they could never bring it to market. Said electric will be the future for bmw, porsche, Benz for their fleet.

  29. I’m with MJones in believing–well, ‘hoping’ better treatments are in a lab right now—aren’t we all. I mean, that’s why we’re here! And it doesn’t seem conspiratorial when one realizes that superior treatments have been shutdown by at least some type of suppression in the past. Two examples come to mind:

    THE STRANGE PREDICAMENT OF RU58841:
    https://www.hairlosscure2020.com/the-strange-predicament-of-ru58841/

    DR. RICHARD LEE — Minoxidil 15% plus Azelaic Acid:
    https://www.hairlosscure2020.com/category/azelaic-acid/

    I don’t know about secret cures and all that, but there was a Cambridge scientist, Regina Hodits that had a cure for the common cold, “but when we discussed this with pharma partners, they were not amused. They thought that the cost of such a treatment would be too high for ever being considered for development.” […] “That event told me that all my science wasn’t actually going to see daylight if I didn’t know anything about economics.” […] “People have become much more disciplined on saying ‘how can I invest into something that, in the end, is going to turn into a product?’”

    How much different would our perspective be if instead of hairlosscure this was just hairlossproduct.

    Is what it is.

    (English Tsuji article from 2019 confirms first human clinical trials will *begin* in 2020. 8. Conclusion and future perspectives: https://royalsocietypublishing.org/doi/10.1098/rsob.190010#d3e1016)

  30. Regarding RU58841, this was 4 years ago and several hair loss sufferers got their hands on it illegally to combat hair loss. Where are they now? Where are the viral YouTube videos of these newly Norwood 1 formerly bald people? Either it didn’t work, or the illuminati had them all killed to keep their hair loss cure safe :-) :-)

    As for Regina Hodits, all things have to make economical sense or they don’t happen. There are so many bogus university projects out there. A cure for the cold will mean losing opportunities to call in sick for work; people wouldn’t take it if it was given out for free.
    On the other hand, a cure for hair loss made by an individual would be so economically viable it would make that person one of the richest people in the world.

  31. The hair loss industry has known for decades that a DHT resistant hair follicle could be implanted anywhere and grow forever (simple as a plant in soil). Therefore, a hair loss cure would be to simply clone follicles in decent numbers. Entire animals have been cloned for decades. China has made genetically modified babies and human monkey hybrids. Body parts and tissues are now being 3D printed. If the industry was truly motivated to clone a little hair follicle as a viable product, they would’ve done it by now. The problem is that eliminating bald people with a one-time treatment would be terrible for the wig, finasteride, propecia, and current HT industries, where they love getting years of recurring payments. In 2007, I saw predictions on CNN and Popular Science that baldness would be cured by 2009 and 2012, respectively. The technology was there, but it vanished. The lack of progress since then has been astounding. Clone a
    some back-of-the-head follicles… That’s the only true cure, and yet it’s so very very unattainable for some strange reason.

  32. Scott, cures are not discovered by individuals. An enormous network of research, clinical and scientific teams and advisors, engineers, marketers, directors, and executives; company partnerships, corporate alliances, biomed institutes, private investors, blah, blah, blah, go into developing a treatment. You don’t need a coterie of evil men to be thwarted. Just indifference.

    “Something as simple as lack of sufficient funding despite successful stage 2 clinical trials can cause a company to stop pursuing highly promising products.”

    —Admin said that five years ago! (Nov 25, 2014) And guess what we were all hyped about: Histogen and Replicel! https://www.hairlosscure2020.com/lessons-from-aderans-and-intercytexs-hair-multiplication-failures/
    (Read the comments)

    Where are we gonna be in 5 years? I thought I knew, but honestly, I don’t.

  33. Maybe it is the government’s conspiring against this as the facial recognition would all need revamped due to so many people looking completely different.

    Sorry admin, haven’t posted in a while and don’t recall my screen name.

    Thanks for the wonderful blog!

  34. Thank you Slick and Tocatta for supporting me. You both said it perfectly. They can grow clone print etc yet the follicle just can’t be done. They just don’t want to release it yet.

    1. Despite your pessimism, you were always optimistic about Follica and Cotsarelis! I thought Cotsarelis was part of both the Illuminati and Masonic Lodge and heavily involved in the conspiracy too…

      1. Hi Admin, yes you are right. But after those results I am extremely disappointed. I’m hoping these are just teaser pics and they release better ones later. As of now, I’m very disappointed in follica.

  35. If you guys really believed that a cure was being suppressed, you would not be on the internet complaining. You’d be teaming up and kicking down doors. Give me a break.

  36. So guys what % of hair loss do you think propecia can grow back. When I say, propecia, i mean finasteride. Might take a topical from a Dr. I did take finasteride for 1 month. I didn’t get any sexual sides….but the first day I had bad breath. Really bad, it smelled like when if you get a filling and they drill on a tooth. I brushed my teeth several times that day….nothing could get rid of the smell lol. Then in Lab before my clinical rotation, I noticed my brain was as sharp at all that month. I have a 3.8 G.P.A taking Pharmacology, Patho physiology, Anatomy and physiology, physics, nuclear chem etc…all the hard “core” sciences. So when my brain was not on point, that’s when I got off it. I took it orally, in the form of proscar, and just bashed it into 4 to 5 pieces.

    So I never gave it a good shot. I am a Nw 2.5ish. So idk how good finasteride would work. I started 4 years ago with hairloss. The one thing that did happen, my hair stylist thought I died my hair jet/dark black. My hair got slightly darker on proscar. So what % did you think topical fin could grow back ( reverse miniature ). How effective has it been for you guys within the first couple years. Again I am around a 2.5 NW with it happening 4 years ago.

    1. If you are a Norwood 2.5 I would say forget about it and go out and live your life. Find the love of your life, travel, study, party, get rich, whatever. Then come back here in 5 years. We will either have a cure for you, or there will be less players to read up on.
      I am a Norwood 5. But courtesy of surgical scars on my head if I take my hair systems off and have an army style hair cut, I don’t just look old, I look like the villain from the blade 2 movie.

      Norwood 2.5 – I don’t even consider that loss. You can’t look like a 15 year old forever.

        1. No. Scars nothing to do with hair loss. The FUT scar was massive when I first had the op and I was worried, but its not visible at all. I am grateful for that.

    2. Thanks for the reply guys. I should mention my 2.5ish NW is diffuse. It makes me feel like a 3. The back of the head on crown is thinned and got recessed on both sides. Nothing close to say Jude law..but…if I comb my hair like Brad Pitt ..on The movie Fiery, 2014 world war 2 movie, it’s hard to tell I have hair loss. When it’s wet though…ouch. Pitt brushes his hair to the side on that movie and back. However, my hair loss was do to a medication, and it never reversed. One doctor seen my blood work and said the previous physician had me on too much and it was clear in my blood work why I lost hair. I won’t lie, my confidence took a big hit. I stopped lifting weights…became a shell of myself. Last time I went out, got hit on etc…but idk. I had a very very low hair line.
      Forgot to add about diffuse.

  37. Yea if I were you I would say forget the pills and lotions and work on kicking butt in school. You will regret it later if your grades slip due to being on a treatment. You seem to have plenty of tools to snag an attractive mate and do well in life.

  38. Hi Derek don’t listen to Scott. Horrible advice. Hop on 1mg of brand name Propecia. If it works for you it will hold your hair as is at nw2.5 for at least 10 years. I started losing my hair at 20. I hopped at the first signs of shedding..nw1.5 diffuse. My hair loss stopped within a few weeks of using it. I got thickening and regrowth around 18 months later. The thinking areas filled in again. Not 100% but it wasn’t see through in the sun anymore. I used Nizoral 1% shampoo and country life Maxi Hair vitamin. I work out 4x a week, eat healthy. That mix stopped my hair loss for 12 years. All the men in my family are nw6 to nw7. So very aggressive. I did get sides for the first 6 months. Libido and some brain fog. That all went away after 6 months. I would not use Rogaine if you aren’t on Propecia. Without Propecia you will most likely go bald. So if you don’t care about hair loss and are content with losing all your hair then take Scott advice. If balding bothers you, makes you sad or stresses you out then hop on Propecia. 80% chance it will stop or extremely slow down your balding. The sides you mentioned about bad breath is the first I heard of. Topical won’t work as well as internal. Take brand name Propecia 1mg for a year and see how it goes. You’ll get some regrowth if you just started balding within the past few years.

    1. Also you can travel, work, find the love of your life, hit the gym, study while being on Propecia. I did :) also don’t ever bank on a cure being available in 5 years. I went to a ht clinic back in 2002 and they told me to hop on Propecia to hold on to your hair till 2010. A cure like hair cloning will be available then. Here we are 10 years later and we are still using the same big 3 drugs lol.

    2. Yes “only use brand name propecia” all others are inferior. They definitely won’t mess up your endocrine system. You can trust me and the “official brand named propecia”.

      “Official brand name propecia, is the only answer to most of life’s problems”.

      Please note I am not affiliated in any way the worlds best treatment for all life’s ills “official brand named Propecia”

      “I am definitely not a shill for the company brand named Propecia”

  39. I’ve always used cheap finasteride prepared for me by my local pharmacy “15 years” 30 euros for 100 pills and I’m doing just fine, never had any side effects.

  40. I would of thought hair cloning would come before that magic injection or pill that actually regrows your hair back – Still waiting on those. Other commenters have said we can clone all kinds of stuff but hair follicles are tricky. Once they figure it out and have these hair farms – Hair transplant surgeons are still in business (getting tons of work), donor region is left untouched and no scars, patients are able to get insane density. I’ve been thinking about getting a HT but I want that to be my last resort. I’m able to style my hair a certain way that gets me by for the moment (thankful for that). I would honestly love to just wake up and go to work without having to style or worry about my hair. I’m currently taking brand name Propecia, 1mg. I was on generic but made the switch recently. If your thinking of taking fin, see for yourself if its for you. If you read and watch every video on side effects, you’ve already planted that seed in your brain. Trying to remain positive that something decent or amazing will come out but by no means counting on it. To all my brothers and sisters going through this hair loss journey I solute you.

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