I have covered Swedish company Follicum numerous times on this blog in the past, including twice already earlier this year. The company is developing a topical scalp hair stimulation product called FOL-005 that is based on the human protein osteopontin. Interestingly, a variation of this same drug will likely be developed by Follicum in order to reduce body hair. Side note: see my post on excessive body hair in men and its correlation with scalp hair loss.
Of the numerous companies in the world that are developing a treatment or cure for hair loss, Follicum is currently the most professional when it comes to its communications and its product development strategy. Their clinical trial time-frames for each stage have generally been accurate over the past few years, and they seem to be on schedule to continue to hit targets over the next year.
Earlier today, I got an e-mail from Follicum notifying me of their achieving a major milestone. The company has now successfully developed a direct-to-scalp topical formulation for their FOL-005 hair stimulation drug. This will in the near future replace their current method of delivery (intradermal injections) of FOL-005.
This newly developed formulation has been shown to be stable when it comes to long-term storage. The company plans to optimize it for large-scale manufacturing.
According to CEO Jan Alenfall, Follicum’s extensive experience in developing peptide drugs has enabled them to develop a stable formulation that delivers FOL-005 directly to the hair follicle.
Follicum Advisory Board
While browsing through Follicum’s website today, I also noticed that their scientific advisory board page seems to have been updated recently. They now have a highly respectable and accomplished group of advisers, many of whom have been covered on this blog in the past. The most well known of these in the hair loss world are Dr. Gerd Lindner (Germany), Dr. Ralf Paus (UK/Germany), Dr Ulrike Blume-Peytavi (Germany) and Dr. Amos Golhar (Israel).
If all continues to go well in Phase II trials, it is not out of the question that Follicum’s hair growth product could be released around the end of 2020 (maybe I am too optimistic — h/t John Doe’s comment).