Dutasteride and Minoxidil Before and After Photos

In my previous post, I showed an incredible before and after photo of someone taking Dutasteride (oral and injection) in combination with Oral Minoxidil. This patient was treated by Dr. Sergio Vañó-Galván from Spain. The doctor has since sent me a number of other before and after photos of his hair loss patients. All of them have seen significant hair growth while on some variation of this Dutasteride (oral and/or injection) and Minoxidil (topical or oral) combination treatment.

I was debating on whether these new photos (see further below) were worth a new post, and finally concluded in the affirmative. Sometimes people forget about the excellent existing hair loss treatment medications out there that have been proven to work really well for many patients.

Of course one must be willing to risk potential side effects of these medications. Most published studies suggest very few people get major permanent side effects from Dutasteride, but it is up to you to do your own research and reach your own conclusions. Note that Dutasteride is only approved in several countries to treat hair loss as of 2019. However, it is approved as an enlarged prostate treatment all across the world.

Dr. Sergio Vañó-Galván is on the organizing committee of the 11th World Congress for Hair Research that will take place in Barcelona in April 2019. He is also on the Board of Directors of the EHRS. i.e., this man is not some run-of-the mill hair transplant doctor operating from a back alley.

Dutasteride plus Topical Minoxidil Hair Growth

For those getting side effects from oral Minoxidil or fearful of taking it, topical Minoxidil is always a good alternative when taken in a combination treatment alongside Dutasteride.

Patient 1: Dutasteride injections plus oral Dutasteride plus 5%  topical Minoxidil at 12-months.

Dutasteride and Topical Minoxidil -- 12 Month Hair Growth

Patient 2: Dutasteride injections plus oral Dutasteride plus 5% topical Minoxidil at 12-months.

Dutasteride plus Topical Minoxidil Hair Growth at 12 Months

Patient 3: Dutasteride injections plus oral Dutasteride plus 5% topical Minoxidil at 12-months.

Dutasteride and Topical Minoxidil Hair Growth Before After

Oral Dutasteride plus Mesotherapy Dutasteride Injections

One can also ignore Minoxidil entirely and just focus on Dutasteride (oral and injection combination treatment) if so desired.

Patient 4: Oral Dutasteride plus mesotherapy with Dutasteride 0.05% once every three months.

Dutasteride Mesotherapy Before and After

Female Hair Loss Treated with Oral Minoxidil

Females are not given Dutasteride if trying to get pregnant. However, females are allowed to take oral Minoxidil at any time if healthy. However, women should note that oral Minoxidil can cause excessive body hair (hirsutism) as a side effect.

Patient 5: Oral Minoxidil 1 mg/day at 12-Months in a female.

Oral Minoxidil Hair Growth in a Female: Before and After

63 thoughts on “Dutasteride and Minoxidil Before and After Photos”

  1. Wow, they are all fantastic results. I’m still hesitant to take these medications for fear of side effects but I’m happy for these featured patients nonetheless.

    1. Hey Daniel,

      I’d definitely try finasteride first. If you are also wary of taking finasteride I’d have you look at this study:

      https://www.ncbi.nlm.nih.gov/pubmed/17655657

      Basically the study shows that men who are told about sexual side effects are more likely to get them. Which means that a large number of cases are from the nocebo effect. If you have already tried finasteride just keep the nocebo effect in mind. It is very powerful, but something that you can overcome mentally.

      A majority of studies have shown about 5% of men get side effects. And I think this research shows why a larger number of people online get side effects.

      I’ve been on finasteride for 2 years with no side effects. I’ve lost no ground either so overall I would say it’s successful. I’m considering maybe switching to dutasteride in a year. I’ve recently started dermarolling. If I get good hair regrowth from that then I won’t have to even take dutasteride.

      1. Thank you, Flow, I really appreciate that information! As I continually lose more hair I consider it more and more. As a single guy, my looks are important to me.

        1. No worries! My biggest regret was that I didn’t start finasteride sooner. I was really afraid of the side effects. I should have started 4 years earlier than I did.

          My hair still looks pretty good with topic, but I’d rather not have to worry about it. Now I’m trying different things to try and get regrowth.

          If you’re hair isn’t too bad I’d say you can weigh your options, if it’s going fast I’d say try getting on finasteride quick.

          Anyway, good luck! Hopefully you find something that works well for you!

      2. @Flow it is not truth! Sides are real and it does not matter if you are awere of it or not. I got them 3 months after usage small .25, and basicly it killed my libido and erection.

        And worth to add, that I was awere of sides and was afraid of them, but in first months of use it actually incrised my libido. So don’t spred this study statistic lies.

  2. the second patient looks amazing, he was literally “CURED”, the only problem with him though might be long term side effects.

  3. Liked here, I wouldn’t mess with Dutesteride or Propecia not to be that annoying person. These pills inhibit enzymes for the lipids (testosterone). These lipids are used for communication in cells and can perhaps alter transcription and translation (DNA/RNA). I can see a treatment having something to do with Mitochindrial damage from oxidation.
    Example this article just read the abstract.

    https://www.nature.com/articles/s41419-018-0765-9

    Funny thing the quest to treat hair loss might be the rabbit hole, that will deepen the lead to treatment of aging. This in my opinion is better.

    FYI. Hair loss will have remarkable treatment by 2032-2035 at the latest. Assuming no WW3, crazy epidemic, or Super volcanic eruption. Why? Computational limits will have breakthroughs making protein twisting and turning more predictable, today that’s only partly thanks to a Google AI breakthrough, but barely still doable and accurate. (Head line is exaggerating AI capabilities btw)

    https://www.sciencemag.org/news/2018/12/google-s-deepmind-aces-protein-folding

      1. Thanks very much Admin. I am thinking of paying him a visit. Incidentally, I use oral Dut and 10mg oral loniten. Still losing ground sadly (v slowly).

  4. Dut is more dangerous than people think. I stopped oral over a year ago and my libido & ejaculations halved and stayed that way. I also get pain in my testicles from time to time. I wish I hadn’t touched it.

  5. Similar results to those shown can be achieved using hair fibers, without the side effects of this more invasive treatment.

  6. Patient 2 AND 3 looked great.

    This is what I consider to be the FIRST real treatment for male pattern hair loss that grows a lot of original hair.

    I am not in a rush to try such a potent cocktail but I will follow it closely on this forum and if no other choices emerge soon then this would strongly be considered.

    Looks like we have 1 treatment. Let’s get a second treatment early in 2019. As a footnote Aclaris should release Phase II JAK results by June.

  7. Just propaganda. There is not logical reason on why topical minoxidil will be less effective than oral minoxidil. In fact, topical should be more effective, since the dose you use is much higher and go direct to the follicle . A none sense, dangerous, already tried it in the past.

    1. You can’t compare topical dosage with oral dosage and conclude in favor of the former without citing data (ml versus mg unit comparison makes it difficult). A number of doctors in recent years have stated that oral is superior to topical, including Dr. Sinclair and Dr. Pathomvanich. A few of the surgeons I know have also started prescribing oral Minoxodil in recent years.

      I do not want to risk more body hair as a side effect so am not on oral Minoxidil, but would not be surprised at all if oral is proven to be superior to topical.

      1. I tried it oral, along with oral spironolactone, back in 2002 was a real popular ( and stupid ) combo on hairsite. Didn’t give me better results than just dutasteride oral and minoxidil topical, of course, it gave me much more side effects .
        When you take it orally, that tiny 5mg or 10 mg have to by pass the stomach, then splitted in the entire body. When you daily apply 2 ml of 5 % minoxidil, you are applying and small molecular weigh drug in a dose of 100mg direct into the scalp each day ! . The only possibility is that the enzyme that convert minoxidil in the body into the active minoxidil, is more present in the rest of the body that in the scalp, but, that are just theories .

        On hairsite, you can still find that posts . w

  8. I’d still be wary of JAK inhibiters, let’s say they do work. They can be potentially be carcigenic in the long run. Inhibiting Kinase disrupts phosphorylation. This disruption of the cycle for immune cell growth and cell cycle can be bad. It interferes with transcription.

    In English: pretend you have a factory that are producing cars. You start throwing wrenches into one of the machines in the middle of the cycle, You are no longer producing cars but giant kinked metal. Essentially the car is a cell and the kinked metal is cancer.

    These companies don’t talk about the potential long term effects or biological process. Why? It’s disrupt potential profit and affect there capital value as a company.

    Now the bright side is you’ll hear more breakthroughs in hair loss Resarch more often in the upcoming years, that will dwarf the past 100 years of biological research.

    1. True. but most people treat their body like a dumpster anyway.

      We smoke/vape, we drink alcohol. People in the US regularly intake food ingredients banned in some countries. Tapeworm in pork, bovine viruses in cattle, mercury in fish. Just add JAK to the pile. I doubt it would make a significant difference when all things are considered, if it even works.

      I doubt it works. They would know by now. It’s like the scientists of old that tried to change copper into gold.

      Any news on Shiseido anybody?

  9. I’m just waiting for follica since it’s the only thing that will be easily accessed and massed produced in the usa. Traveling to Japan for sisheido sounds difficult for those of us with full time jobs. Two trips required, cell injections, a very new type therapy dealing with cell injections. Etc. I might be over reacting but I’d rather get follica done by my local dermatologist or hair transplant doctor then apply the topical in my own home. 100cm2 new hairs is probably more than what sisheido will do. Upside with sisheido is that it will make our hairs immune to the dht and it’s one treatment per few years. Just wish these companies would hurry the fk up already before it’s too late for me to save the hair I left. 17 years waiting for new sht….exhausting lol.

    Ps. Thanks for the blog admin, I know I complain like a little girl but your site does give me hope and I know you are a legit dude unlike other hair loss forum admins…won’t say who but we all know who lol.

    1. Waited 17 years for a cure, but won’t make 2 trips to Japan?

      The flight is longer from the UK, but let me tell you that if those Pokémon enthusiasts/robot makers invent a hair loss cure I will be on the first flight out.

      Hell, I would go to Iran. I would go through the painful months of getting an Iranian visa and forfeit the rights to my visa-free entry to the US because I had been to Iran.

      1. I totally agree with this. I am literally here waiting Pockets full of cash to throw at a viable option. Where ever when ever.

  10. Lol keep on waiting mjones…i don’t think anything in near future will be coming…maybe like in 10 years but not now…i have decided either to shave it or get another fue at least it will give a decent look

    1. Farhan, FUE plus SMP is great for a closely trimmed look of maybe 1/8″ (FUE provides a little 3D fuzz for natural texture). That really is a partial cure to continue looking young and not balding IMO.

      Unfortunately for me, that’s not an option with my FUT linear scars. Never get that.

  11. Hi Farhan, yeah you are probably right buddy. It’s all a waiting game. I still thing big players at Rogaine and merck are blocking or making it very difficult for new drugs to replace their stone age drugs. I am thinking of fue, but I work a face to face job with customers and can’t look all bloody and weird for a month or two. My customers would dip out. Hopefully miracle will happen and something better comes out asap!

    Scott- it’s not the traveling but more of not being in Japan if something were to go wrong with cell injections. Here I could drive to my derm. I don’t know I just think it could be a problem. Maybe I’m over thinking it.

  12. Please someone explain to do mesotherapy with Dutasteride.

    How yo convince and ask my doctor to give Dutasteride injections in India?

    1. Not recommended at all if the doctor is new to this. In fact, even with an experienced doctor, I would be wary about getting Dutasteride injections until more studies come out showing results and side effects.

  13. Has anyone an idea about the process of Follica? They expect to initiate their pivotal study in the first half of 2019. So this could be immediately the case or in like six months. Maybe they have already completed their optimization study?

  14. These results are very scientifically interesting and look promising, however, there is a case to be made for the tightness of the scalp. Why are doctors and researchers not interested in finding a way to relax the scalp so that follicles are not constricted? Is this not a area worth looking into?

  15. This could be interesting:

    A clinical trial from Cairo University will ‘assess the Role of the JAK-STAT Pathway in the Pathogenesis of Male Androgenetic Alopecia’

    Androgenetic Alopecia and the JAK-STAT Pathway:

    “It is a well known fact that the JAK-STAT pathway plays a pivotal role in the pathogenesis of alopecia areata.[…] However, whether this pathway plays a role in other hair loss disorders remains unclear. Our study aims at assessing STAT3 levels in male patients with androgenetic alopecia. We hypothesize that STAT3 levels will be elevated (due to a previous study proving that JAK-STAT pathway is involved in non-immune mediated hair loss in mice).
    https://clinicaltrials.gov/ct2/show/NCT03694067?cond=Androgenetic+Alopecia&rank=5

    1. Might be a moot point if Aclaris comes through by this June. Waiting diligently for the results a potential breakthrough.

  16. Hello admin,

    Sorry if it’s the wrong place to post this here, but I might have some interesting info.

    Poietis, the french start up that has a partnership with L’Oreal for printing 3D and 4D hair follicles, got a funding of 5 million euros in March 2018.

    This funding will serve to accelerate the research, not only in the hair research field. They would like to get involved in regenerative médecine in general (liver…).

    They plan to use the technology in humans in 2021 ( sorry I don’t know if it’s commercial release or beginning of clinical trial, but I think it’s probably the Later).

    Here is the link of the paper but it’s in French :

    https://objectifaquitaine.latribune.fr/innovation/2018-03-27/bio-impression-poietis-leve-5-m-pour-se-rapprocher-du-bloc-operatoire-773224.html

    1. @ Kevin … I really think this will be quite interesting in the next years and maybe does not need Long Trials. Also big Player BASF is involved … and they dont Need Crowdfunding :-)

      1. @admin can you make an updated post on iRestore laser treatment? that has 800+ reviews on amazon and an avg of 4/5 stars
        does it really work?

        1. Not this exact brand but I got the same type of product 3 years ago and used it every other day as instructed for at least 6 months. It made no difference. The laser caps are the most expensive gimmick of all the so-called cures and the manufacturers should be closed down. Sorry if this is not the response you wanted.

  17. Patient number 3 has incredible results (number 2 also) and that this is an Excellent treatment that really works. Just that the cocktail is too much for me to try. But nice to have a fallback.

    John Travolta has embraced the bald look. I say we should embrace the hair look for all of us in 2019. Another treatment, hopefully not as potent as the one above, is coming in 2019.

  18. FYI on Frequency Therapeutics raising 42 million as they are completing Phase 2 on ear hair regeneration. https://www.businesswire.com/news/home/20190107005112/en/Frequency-Therapeutics-Completes-42-Million-Series-Financing This is the company focusing on progenitor cell activation and can culture progenitor cells in an unlimited number in vitro side stepping the hurdle of culturing stem cells. They are actively working on a solution for androgenic alopecia. Not an immediate possibility but solid platform and they are moving fast.

  19. Very lively couple of microneedling threads on the new research section of Hair loss talk, I can vouch that it seems to be working too – lots of great anecdotal success!

  20. 2019 is going to be the year of Big Hope as things start to fall together. I have no proof just that things are moving forward and its just a matter of time.

    I consider the article above to be One nice alternative although too much chemicals. Hoping for a few more treatments by end of this year or at least knowledge that real treatments will roll out soon.

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