I previously covered in detail the recent groundbreaking results pertaining to JAK inhibitors in treating alopecia areata. In particular, from the bone marrow cancer drug Ruxolitinib (Columbia University — Dr. Angela Christiano); and arthritis drug Tofacitinib (Dr. Brett King).
Columbia University Alopecia Areata Study Enrollment
Columbia University is now expanding its testing to cover more volunteers and a wider range of JAK inhibitor and related anti-inflammatory drugs. Here is the their Alopecia Areata Study Consent Form and Inquiry Response Form. In the details, they state the following:
Current study status:
Ruxolitinib — Closed to enrollment. Study procedures ongoing..
Abatacept — Currently enrolling. Total number of subjects to be enrolled: 15.
Tofacitinib — Enrollment to start approximately Sept.-Oct. Total number of subjects to be enrolled: 10-15.
Injection steroids/Triamcinolone (Kenalog) — Open to enrollment.
Sites: Columbia University and the University of Minnesota.
Hi,
I have read, with enthusiasm, the posts about Ruxolitinib and Tofacitinib, but now I see the are more drugs being tested by the same people. Are there more information about those drugs? Abatacept and Kenalog specifically.
Thank you!
Hi Ejav,
Abatacept seems to be another arthritis drug, but not a JAK inhibitor like Tofacitinib. Seems to be safer with much more history behind it than Tofacitinib, but you need to discuss this with your doctor and not take my opinion to be reality as I have not done much research on this.
Triamcinolone (Kenalog) seems to be a corticosteroid that has been used for many years.
I suspect that neither will give results as impressive as Ruxolitinib or Tofacitinib.
I’d like to know if people stops the medicine and hair falls again? Or it’s like roacutan for acne, you take it 6 months ,stops, and acne never comes back.
Anyway I’m in love with Dr. Angela and the new discoveries in any kind of alopecia, even hoping too see something new about MPB.
Dr Angela, God bless her.
I am pretty sure that you have to take these medications permanently. Or more accurately, till a better cure comes out.
Will any of these work
For mpb?
I hope those medicines could work on MPB as well.
Hi guys!
I was just wondering if Comlumbia stated anything regarding eyebrows and beard, or are these drugs only used for alopecia areata totalis (hair only). I have big spots without hair on my head, I am also missing approximately 50% of my beard and one of my eyebrows fell off. Everything is fine on the rest of my body tho. Should I keep my hopes down?
Thanks a lot! (Sorry for my average English)
-Joseph
JAK Inhibitors show complete reversal (so far) in all types of AA (not MPB)
does anyone know anything about argan oil and hair loss?
Hi, im from the uk and have suffered with alopecia universalis for over 20 years. I would love to know more about the developments and ask if there is any scope for testing in the uk?
Great news anyway
Hinesh
I’m seeking a cure. I went to see Dr. Brett King and I was left feeling quite hopeful three months ago. However, I have not heard from anyone from his office or from this program and I’m feeling quite frustrated. It is not just my hair this my heritage and it is a reflection of my health. HELP
My daughter is five years old now and she has suffered from AA for almost two years. So glad to know that there is such a research on AA. Thank you! May I know if there is any measurement the parents can take for young kids who lost hair? I just noticed that volunteers should be over 18 years old. Anyway, appreciated!
Hi river,
Sorry to hear that. I would recommend trying to get in touch with Dr. King or Dr. Christiano if possible. Hopefully you have tried to find and join online forums and groups that deal with Alopecia Areata? Keep us posted on what works for you.
Best Wishes.
trying to find dr.clyne’s web site for alopecia , My daughter has a severe case of alopecia areata , she had a full set of hair and in 60 days all of her hair fell out very devastating for her and very depressed .can you share some info .. thank you
Number on top here:
http://www.cumc.columbia.edu/hematology-oncology/about_us/raphael_clynes
If he does not respond, call the Dr. Angela Christiano at the same place, or the University Medical Center.
Best of luck.
Im only 20 but ive been dealing with very severe alopecia areata practically my entire life. Ive lost about 75% of my hair and no treatments work for me. This disease kills my confidence. I hate hiding behind wigs. Its sad when a man has more hair than you! I hate that this life was chosen for me. I hate hearing the words “There is no cure”. 12 years of dealing with this disease and I will never ever ever get use to it I hate it so much . Hopefully these wonderful doctors can find a cure for us people living with this curse.
Hi,
I am recently developing AA, and I was wondering if there is any news on the final results on the study on Ruxolitinib. I read that the study would be finalized in August 2015, very curious on the outcome.