TissUse Smart Hair Transplants in Japan

Earlier this month, Germany’s TissUse entered into an agreement with Japan’s J.Hewitt that may have significant implications for hair loss sufferers. This agreement is in regards to the licensing and further development of the former’s Smart Hair Transplant (SHT) technology in Japan.

TissUse Smart Hair TransplantFuji Maru from Japan first noticed this development and has covered it in detail here. TissUse also has a press release page where you can find the story towards the top for the time being.

Among the main scientists who developed TissUse’s technology is the well known Dr. Roland Lauster. He is now on the company’s advisory board. In the past, Dr. Gerd Lindner also used to be on that list.

As has been mentioned numerous times by myself and many others over the past several years, Japan’s government is heavily promoting regenerative medicine in the rapidly aging country. One of the main ways it is doing so is via speeding up the usually lengthy and expensive clinical trial process (which is common in most developed countries).

Smart Hair Transplants

In the case of SHT, the process is autologous in nature. So clinical trials are possibly not required, or will be fairly short in duration if required.

Smart hair transplants theoretically provide unlimited donor hair. By isolating cells from the dermal papilla and then culturing and multiplying them, this procedure supposedly forms neopapillae. According to TissUse:

“Neopapillae are the precursors of hair follicles which have been shown to grow hair follicles under controlled conditions in vitro. Each of these neopapilla has the potential to form a brand new hair follicle.”

27 thoughts on “TissUse Smart Hair Transplants in Japan”

  1. This seems very promising, but haven’t we heard this before regarding Tsuji? cause I thought Tsuji also provides unlimited donor hair from small punch biopsies via cloning and subsequent transplantation.

  2. In which phase of development is this?
    Will this be released firstly in Japan because of the law requirements there?
    Any possible release date??

    Many questions because of my excitement!

  3. I was literally about to bite the bullet and even though im terrified start on finasteride. Im hoping that more information comes through soon to hold out hope!

    1. Hi Andy, I was a hairloss sufferer too. I have been on finasteride and I can tell you its a complete waste of time and effort. It doesn’t work. Its a perceived misconception throughout these years. It is good enough to just SLOW hairloss. It doesn’t STOP or REVERSE them.

  4. At least five years away!
    It’s reassuring, though, that different groups are developing or intend to develop cell-based approaches.
    By 2030, I firmly believe, effective treatments will have been well-established.
    No sooner than 2025, though. Hehe

    1. they replied to me!

      Thank you very much for reaching out to us and for your interest in our SHT technology.

      We are still in the very late preclinical development stage but plan to move to a first clinical trial in the next years. We have just recently signed an agreement with a Japanese company to bring the treatment to the Japanese market

      However, this also means that it will still take a couple of more years before SHT will be broadly available as an alternative to conventional hair transplantation methods.

      Best regards,

      The TissUse Team

      1. They just in January had first person paralyzed use stem cells in surgery and he regained control of upper body. Is even lifting weights. Since I dont know if I can post links here type in @admin …these keywords:

        First Paralyzed Human Treated With Stem Cells Has Now Regained His Upper Body Movement

        1. Thanks. Most links are ok, but some go to spam folder and I miss them since there are 100s of spam comments in there daily.

  5. Thank you very much for reaching out to us and for your interest in our SHT technology
    We are still in the very late preclinical development stage but plan to move to a first clinical trial in the next years. We have just recently signed an agreement with a Japanese company to bring the treatment to the Japanese market.
    However, this also means that it will still take a couple of more years before SHT will be broadly available as an alternative to conventional hair transplantation methods

  6. The reason I believe this is positive news is because it will remind the other major players in the race that they cannot just sit on their IPR and clinical data. If they don’t release something soon they will be confined to history, just like the early enemies of Microsoft and Apple.

  7. Yes this is the most advanced technology for hair cloning ( even better than Tsuji) but it will be available later than Tsuji

  8. Very intersting, especially since they mentioned market release in a couple years. 2 to 3 years. If that is the case this is huge news. Good to see another player in the game. We shall see what happens……

  9. You know seeing 3 4 companies competing is when you know were moving into reality like californias green rush there’s delivery bilboards and walgreens selling marijuana unheard of in the south I had to take pictures for people to believe it. The more competition the better for all of us. There will be a strong sense of urgency when Tsuji lights the score board because then its about survival and the rush is on.

    Very positive news here admin. When we start talking unlimited donor hair were talking about a real permanent solution not some cream or pill with 15% whatever. the real deal.

    1. Agreed, the only solution to fit all people is this. If I was a rich man id be backing one of the main contenders right now.

  10. It’s way too early in the game to get excited about a company (using DP cells) that has not even completed a proof-of-concept yet. Especially considering the known issue of human DP cells losing inductivity when cultured. Solve this issue, and the delivery methodology becomes moot.

    That said, the direction of this research is surely interesting.

    1. I believe Terskikh and Tsuji have already stated that has been achieved in their labs years back now. Some of these articles have been saved and stored on this website.

      1. They can’t multiply them more than x1000.
        That’s enough for the Organ Germ Method, but I doubt it’s so for the DP Method.
        Still, more players is always good!

  11. Man if this is true then I could probably get the beard I’ve always wanted as well as a great hairline haha balding with sparse facial hair is a tough look

  12. I guess Japan is more relaxed about side effects, it one of the only two countries where Dutasteride is actually approve for Hair loss and even at higher dose than for prostate.

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