Hair Loss Cure 2020

Revivogen® shampoo has been on the market for over 20 years. It is one of a select few renowned hair loss products that I never reviewed. I even used it once over a decade ago. It is ranked amongst the best hair loss shampoo products in the world.

The Revivogen line of products were developed by California-based board certified dermatologist Dr. Alex Khadavi. The company’s Facebook page and Instagram page have updates on any new sales , discounts, coupons and product releases.

Revivogen Bio-Cleansing Shampoo

The Revivogen MD Bio-Cleansing Shampoo for thinning hair contains a number of natural anti-DHT ingredients. The company also sells a PRO line of bio-cleansing shampoo.

The shampoo removes sebum and impurities from the scalp. This creates a healthy environment for stimulating hair growth and preventing hair loss. A number of people have discussed this product on Reddit and on hair loss forums over the years.

On Amazon, the Revivogen shampoo has an average rating of 4.3 out of 5 stars as of the time of writing this post. This is based on almost 500 customer reviews, although no-one has posted any before and after images. You can also purchase the bio-cleanser and hair thickening conditioner combination package.

Revivogen Scalp Therapy

The Revivogen MD and PRO lines both include the company’s scalp therapy serum products. The product’s reviews on Amazon currently average 4.0 out of 5 stars.

This dermatologist formulated, botanically rich hair serum is a topical, leave-in hair loss solution. It is effective for all hair types and is safe for color-treated hair.

The Revivogen MD scalp therapy serum contains natural dihydrotestosterone (DHT) blockers. It is clinically proven to inhibit both type 1 and type 2 5-alpha reductase. This should ultimately reduce hair shedding and thicken existing hair, although results will vary.

How it Works

The Revivogen shampoo and conditioner products work by inhibiting the adverse effects of DHT and strengthening existing hair. Note that if you purchase all three products, make sure to first lather and rinse the Nizoral shampoo. Then apply the conditioner.

The serum is its own separate treatment. It will require 10 or more sprays in large thinning areas of the scalp. Or just one or two sprays in small balding spots. Make sure to then leave the serum on overnight, or for at least for 3 hours in the daytime.

Ingredients

Among the key side-effect free natural ingredients in Revivogen include:

Gamma linolenic acid (GLA), alpha linolenic acid (ALA), linoleic acid and oleic acid. All of these are essential fatty acids that are found in plant oils. These fatty acids have all been proven to inhibit the baldness causing 5-alpha reductase enzyme.
Saw Palmetto extract, which is a natural dihydrotestosterone (DHT) inhibitor and mild anti-androgen.
Azelaic acid, vitamin B6 and zinc. The synergistic anti-inflammatory activity of these three compounds against 5-alpha-reductase is powerful.
Procyanidin oligomers (Proanthocyanidin). These naturally derived ingredients have been shown to stimulate hair growth to a similar extent as Minoxidil (Rogaine).
Caffeine, aloe vera, castor oil, grape seed extract and more.

Note that since Revivogen shampoo is a natural product, it does not require US FDA approval in order to be sold to the public.

There is also a published study that examines Revivogen’s impact on testosterone metabolism. In general, I would still prefer Minoxidil as a first line topical hair growth treatment over a shampoo.

Make sure to also check Wal Mart for potentially cheaper prices of this popular hair loss product. Also see my posts on competing products such as Nioxin and Shiseido Adenovital and Revita.

Revivogen Before and After

On Revivogen’s website, you can see a number of customer testimonials with before and after photos. Also check out their UK site. When I used Revivogen shampoo many years ago, I did not take any photos. However, I am certain that I did not see any kind of major hair regrowth. Perhaps just an overall improvement in hair texture.

Frequently Asked Questions

Below are some frequently asked questions about Revivogen shampoo and scalp therapy.

Does Revivogen block DHT?

Yes, but to a limited extent. Revivogen contains a number of natural DHT inhibitors, such as Saw Palmetto. The shampoo also contains a number of 5-alpha reductase inhibitors.

What ingredients are in Revivogen?

The active ingredients in Revivogen shampoo and scalp therapy include: saw palmetto; gamma linolenic acid; alpha linolenic acid; linoleic acid; oleic acid; azelaic acid; vitamin B6; zinc; procyanidin oligomers (proanthocyanidin); caffeine; aloe vera; castor oil; and grape seed extract.

Around 90-95 percent of people with hair loss suffer from androgenetic alopecia (AGA), also known as male pattern baldness. Just 1-2 percent suffer from alopecia areata (AA), aka patchy hair loss due to an autoimmune problem.

However, in recent years, alopecia areata (and the related alopecia totalis and alopecia universalis) have been in the news almost every week. Most of the coverage tracks miraculous before and after hair growth results via the use of JAK inhibitors. I covered this subject close to ten times a few years ago. More than 300,000 Americans currently live with severe alopecia areata.

FDA Approves Baricitinib for Alopecia Areata

Yesterday, the US FDA approved Olumiant (baricitinib) oral tablets to treat adult patients with severe alopecia areata. This drug is sold by Eli Lilly and Incyte. This once-a-day pill is the first ever approved in-disease systemic treatment for adults with severe alopecia areata (AA). Monthly cost without insurance will be $2,500.

Olumiant is a Janus kinase (JAK) inhibitor that blocks the activity of a family of enzymes. This in turn interferes with the pathway that leads to inflammation in alopecia areata. Note that Olumiant is already approved for treating moderate and severe rheumatoid arthritis. It is available in 4 mg, 2 mg and 1 mg tablets (with the recommended dose for AA being 2 mg per day).

The approval for alopecia areata was based on Lilly’s BRAVE-AA1 and BRAVE-AA2 trials. These were the largest Phase 3 clinical trials ever completed in humans suffering from AA. Both trials were led by Yale University’s Dr. Brett King.

Patients in the Lilly study experienced relatively mild side effects, including slightly increased risk of acne, urinary tract infections and other infections. Those side effects were easily treatable or improved without treatment. Around one-half of patients regrew their hair after one year of treatment.

Baricitinib Hair Growth in Alopecia Areata Patients. Before and After. Source: Dr. Brett King et al in the New England Journal of Medicine.

Note that it was Aclaris Therapeutics which originally got the patent rights for the use of baricitinib in treating hair loss in 2017. Earlier this year, I also discussed some phenomenal baricitinib hair growth results. The before and after photos (seen above) are courtesy of Dr. Brett King and his work.

JAK Inhibitors

A number of other JAK inhibitors have shown impressive results in treating alopecia totalis and universalis. Among the more famous of these include ruxolitinib, tofacitinib and decernotinib. See all my past posts covering JAK inhibitors for more details.

Pfizer (Ritlecitinib) and Concert Pharmaceuticals (CTP-543) are also planning to release JAK inhibitors to treat alopecia areata in the near future.

Revivogen Shampoo and Scalp Therapy