ISHRS 23rd Annual Meeting Begins Today in Chicago

The 23rd ISHRS annual meeting just started today in Chicago, Illinois. Unlike in years past, I did not have time to write a post about this important event prior to it commencing.  In any case, I will update this page with more details over the next several days as the conference proceeds. The meeting runs from September 10-13.

Day 1

— By far the biggest and most exciting news thus far on the first day is Kerastem’s update. I discussed Kerastem in detail last year. In the new update, their small trial on 9 patients in the UK resulted in around a 20 percent hair growth from just 1 injection in all patients.  It does seem, however, that the treatment will not help those that are totally bald. These results clearly support growing research from recent years that suggests a very strong link between fat cells and hair cells.

Some key quotes from Dr. David Perez-Meza:

“The authors reported a 100% patient response rate to the Kerastem Therapy at 6-months.

We are very pleased with these initial clinical outcomes, as they represent results that are on par or better than those of traditional medical approaches to hair loss.”

— A really interesting summary of the finally available Okuda Papers from 1939 was presented by Dr. Jimenez.  In those papers, the now deceased Dr. Shojui Okuda covered his own research related to hair transplantation as well as older groundbreaking research from the 1800s!

— Valerie Horsley’s hair follicle stem cells presentation summary.

Day 2

— Dr. John Kahen’s PRP summary. Only a single patient, but great photos. Significant increase in hair density after 6 months and, interestingly, the patient saw his light brown hair become dark brown.

— Dr. Jerry Cooley presented something on bio-enhancements. Link not yet available.

— It was announced on Twitter that this was the largest attended ISHRS meeting to date in its 23 years of existence.

Follica Update

I have discussed Follica briefly in various posts on this blog.  For the most part, I have assumed that the company either has insufficient funding or its owners have very limited  interest/ motivation to ever come out with their seemingly very safe technology involving wounding and the creation of NEW hair. Follica was founded in 2006, so I stopped looking at them seriously after almost a decade of waiting.

However, today Follica was issued an important patent governing its wounding technology (it seems like the patent will also cover the application of some compounds after wounding).

Moreover, in my brief updates post from last month, I mentioned Dr. Cotsarelis being granted a new patent related to FGF-9 and hair growth (he filed for the patent in 2014).  Follica’s technology is based on work done by Dr. Cotsarelis, and it seems like one of the things that the company might do after wounding is to add the FGF-9 growth factor into the scalp?

I am still not overly optimistic about Follica, since there are 100s of examples of patents issued in the hair loss world without any of them actually resulting in a decent treatment for hair loss. Nevertheless, it is great to see Follica back in the news.  Among hair loss researchers, Dr. Cotsarelis seems to be the king of patent holders.

The following quote regarding Follica’s technology from this 2013 article is quite encouraging:

Although Follica has released few details on their proprietary procedure, the general idea is clear: their patented minimally invasive “skin perturbation” device removes the top layers of skin, causing the underlying skin cells to revert to a stem-like state, after which a molecule is applied topically to direct the formation of new hair follicles.  Indeed, Follica has already done preclinical and clinical trials, says Olle, “all of which confirm that we can consistently create new hair follicles in mice and in humans. As far as I know, no other approach has been able to achieve that.”

Interestingly, Dr. Ken Washenik is a scientific adviser to Follica. The company itself is owned by PureTech, which owns a dozen healthcare sector companies as of today.

Finally, it is worth reading the 100s of comments to xconomy.com articles on Follica from 2013 and from 2011.