Category Archives: Dihydrotestosterone (DHT)

DHT Blocker from Advanced Trichology

In 2020, I wrote a post in regards to the ultimate natural dihydrotestosterone (DHT) blocker. Blocking DHT levels significantly results in hair regrowth in most people. The 5-alpha reductase inhibitor drugs dutatasteride and finasteride are extremely effective at reducing DHT levels.

Natural products can also reduce DHT levels, albeit to a much lesser extent in comparison to the above two drugs. For those who are getting side effects from drugs, natural products can be of some use in at least reducing hair loss. In some cases, they can even lead to modest hair regrowth.

For example:

  • A widely cited 2012 study from Italy found that 38% of people with male pattern hair loss who took saw palmetto experienced an increase in hair growth. In comparison, 68% of those taking finasteride saw an increase in hair growth.
  • More recently, a 2023 study from India found that oral and topical formulations of a saw palmetto based oil led to a 29% and 22% increase in hair growth, respectively. The oil contained 2-3% β-sitosterol.
  • Of most significance, a 2020 systemic review of five clinical trials and two studies concluded in favor of saw palmetto benefiting hair growth.

Advanced Trichology DHT Blocker

Advanced Trichology DHT Blocker
Advanced Trichology DHT Blocker with Natural Ingredients.

Advanced Trichology (US) makes one of the most popular natural ingredient based DHT blockers in the world. On Amazon, the company’s DHT  Blocker product currently has 10,400 reviews with an average rating of 4.2 out of 5 stars. Quite impressive for a natural DHT inhibitor.

Among the key natural ingredients in this product include:

  • Saw palmetto extract.
  • Green tea leaf extract.
  • Nettle root powder.
  • L Lysine HCI.
  • Grape seed extract.
  • Pygeum bark.
  • Pumkin seed extract.
  • Grapefruit seed extract.
  • Chicory root extract.
Advanced Trichology DHT Blocker Ingredients
Advanced Trichology DHT Blocker: Key Natural Ingredients.

Advanced Trichology also sells a FoliGrowth capsule product for thicker hair. It currently has 13,900 reviews on Amazon with an average rating of 4.2 out of 5 stars. FoliGrowth contains 28 herbs and vitamins, including: vitamin A, vitamin C, vitamin D3, vitamin E, thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid, iron, iodine, selenium, manganese, Foli-GROWTH™ ultra hair proprietary blend, PABA, R- lipoic acid, inositol, Opti MSM®, fo-ti root, saw palmetto extract, pine bark extract, bamboo extract, L – cysteine, hyaluronic acid and choline.

DHT and Skin Disorders

Finasteride and Dutasteride Dosage and DHT Reduction
A comparison of DHT reduction via Finasteride and Dutasteride.

Over the years, I have mentioned a number of times that people with androgenetic alopecia (AGA) tend to have higher rates of scalp itching, dandruff, seborrheic dermatitis, sebum production and inflammation. I feel that treating these conditions can improve the chances of your hair follicles surviving the onslaught of dihydrotestosterone (DHT) for a little longer.

I have also discussed my own positive experiences in treating dandruff with shampoos, in particular Nizoral and Head & Shoulders. Also see my summary on natural treatments for dandruff.

DHT and Skin Disorders

I was not planning to write this post, but earlier today I saw an interesting new video on DHT and skin disorders. It is an hour long and I only watched one-half of it (via the timestamp subjects that I found of most interest).

The narrator analyzes a number of studies and also discusses Clascoterone (Winlevi) and androgen receptor antagonist KX-826 (Pyrilutamide). I find the video a bit disjointed, but it is a great overall effort. He covers acne, dermatitis, overactive sebaceous glands (and their suppression), scalp inflammation and other DHT-mediated skin disorders.

Of particular note, the video specifically breaks out Clobetasol (a corticosteroid) and Tacrolimus (an immunosuppressive agent) to combat scalp inflammation. Clobetasol propionate shampoos can be purchased online, but require a prescription. The same is the case with Tacrolimus ointments and creams. Do make sure to talk to your dermatologist if you ever try such products. And watch out for any potential side effects, especially with long term use.