Category Archives: Amplifica

Amplifica Gets Moving

Among newer companies involved in trying to cure hair loss, Amplifica (US) is particularly interesting. It was founded in 2022 by Dr. Maksim Plikus, who I have covered many times on this blog.

Update: March 27, 2023 — An interesting new UCI article covering the work of their hair scientists Maksim Plikus and Natasha Mesinkovska. Per Dr. Plikus:

“Most likely, SCUBE3 would be microinjected less than a millimeter beneath a person’s skin, a “fairly painless” process that would have to be repeated periodically to maintain hair growth”.

Human trials on Amplifica’s lead compound (likely not SCUBE3, my original assumption) are expected to begin later in 2023.

New Agreements with Ingenza and University of California

January 26, 2023 — Amplifica signed an exclusive licensing agreement with “The Regents of the University of California” for a proprietary pipeline hair growth molecule (SCUBE 3) that has been in the news a lot lately. Key quote:

“This early-stage compound (SCUBE3) will now be referenced as AMP-601 and is currently undergoing pre-clinical testing at Amplifica.”

January 20, 2023 — Amplifica to collaborate with UK-based Ingenza in order to advance novel alopecia treatments involving the former’s signaling molecules and proteins.

November 14, 2022 — Make sure to watch the below interesting recent video presentation by Dr. Plikus:

October 24, 2022


I previously mentioned new hair loss company Amplica in my post about Dr. Maksim Plikus’s research on the Scube3 molecule for hair growth. He partnered with Dr. William Rassman to create Amplifica. The latter announced his involvement via a Reddit comment in July 2022.

Amplifica Signaling Molecule
Amplifica announcement by Dr. Rassman on Reddit.

Earlier today, it was announced that Amplifica just completed a $11.8 million Series A Financing round. These funds will enable clinical development of the company’s lead products to treat androgenic alopecia.

These lead products are listed as “AMP-303” and “AMP-506”. The press release states that they expect to initiate first clinical trials in fiscal year 2023.


Amplifica, Dr. Maksim Plikus and Hairy Moles

Note that Amplifica was first mentioned in a 2020 news article in regards to the new company’s interesting work in relation to hairy moles. At the time, a team led by Dr. Plikus discovered that molecules from moles that grow excessive hair can induce follicle growth when administered anywhere on the skin.

Make sure to also read my past posts on Dr. Plikus and his many areas of hair loss research breakthroughs. His team is based at  the University of California, Irvine (UCI).

Amplifica is yet another new company added to my main page on hair loss research around the world.