Monthly Archives: May 2015

Coen Gho, Hair Stem Cell Transplantation, HST

Dr. Coen Gho: The Original Hair Regenerator

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Ever since I first became interested in hair loss research and hair biology 15 years ago, around a dozen persons have stood out from the rest. By that, I mean in terms of the intense frenetic online coverage that they received in hair loss forums and newsgroups. I have probably mentioned all of these individuals on this blog by now except for one: Dr. Coen Gho and his Hair Science Institute.

Update: April 2021 — Dr. Gho co-authored a new study titled “From Appendage Development Toward Future Human Hair Follicle Neogenesis.”

Dr. Coen Gho

Around five years ago, Dr. Gho became the most talked about hair transplant surgeon on hair loss forums (replacing FUE pioneer Dr. Ray Woods in popularity). Dr. Gho claimed that he could: extract donor hair from the back of the scalp; implant it in the frontal or crown region recipient site; and yet the donor region would still regrow all its original hair while the recipient site would also grow the new (transplanted donor) hair as is expected in all hair transplants.

His method would never lead to donor hair depletion at the back of the scalp (the biggest drawback of hair transplants). In essence, this represented a cure for hair loss as you could keep getting hair transplants and not deplete donor hair. Perhaps this strategy only works 2 or 3 times and I missed that in case Dr. Gho ever said so. However, even if it worked only twice, such donor hair multiplication or regeneration would essentially be a cure for hair loss for those at Norwood Scale 2 to 5.

Dr. Gho was already reasonably well known online even 10-15 years ago, but two things helped him become truly renowned starting around 2010:

  1. His Netherlands based company’s focus on documenting procedures via well made videos, including on local or internet celebrities (e.g., see here and here).
  2. His appearance on The Bald Truth radio show.

Dr. Gho can be cocky at times, with the best example being his insult (“If he had opted for our technique, Wayne would have avoided looking like Quasimodo”) of Wayne Rooney’s pretty decent hair transplant.

Dr. Gho’s Hair Stem Cell Transplantation (HST) Technique

Dr. Gho’s partial longitudinal follicular unit transplantation (PL-FUT)” Hair Stem Cell TransplantationTM (HST) technique details are presented here. It does make logical sense to me that some leftover stem cells regenerate donor hair while the transplanted relocated stem cells also grow hair in the previously barren recipient area.Dr. Gho has also had his work published in some prestigious journals (e.g., see here and here).

My Thoughts

I initially used the word “maybe” in the title of this post, when describing Dr. Gho as being the original hair regenerator. This was because ever since Dr. Gho came on the scene, a number of other hair transplant surgeons have claimed to be able to do the same. However, most of these surgeons have little evidence to support their claims or are just in the initial research and experimentation phase of their work. Some studies do describe successful hair regeneration from transected follicles.

This is not to say that Dr. Gho’s results are as revolutionary as one would have expected after all the great publicity he has received and after the initial excitement generated from his journal publications. I have serious doubts about how successful his regeneration/hair multiplication is (hence my use of the word “maybe” in the title of this post).

Online hair loss forum posts have largely been skeptical about Dr. Gho’s ability to regenerate hair via his “partial longitudinal follicular unit transplantation (PL-FUT)” Hair Stem Cell TransplantationTM technique. Some people think that even if the technique works, in all likelihood the donor hair and the recipient hair will both be thinner than normal. One of the studies from Dr. Gho that I linked to earlier concludes that the hair in both sites is of the same original thickness and caliber.

A number of hair transplant surgeons such as Dr. Ray Woods and Dr. William Rassman (via the no longer operating hasci-exposed website) have also expressed serious doubt about Dr. Gho’s technique. Dr. Woods does suggest that he and others have seen a 5 percent regeneration of transected hair follicles, and this is a fascinating phenomenon. Why can’t scientists/surgeons do better than 5 percent?

Irrespective of the probability of HST regenerating donor hair or not, most of Dr. Gho’s patients who have posted online seem to like their hair transplant results. So thankfully, the doctor at the very least seems to be a good hair transplant surgeon.

Bald Truth Talk, Biohacking, Chlorine Dioxide, Eri Gentry, Hairlosshelp, Liu Xuewu

Mr. Liu Xuewu — For Your Tremendous Efforts, I Will Promote You

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In 2014, a Chinese person by the name of Liu Xuewu contacted me about a chlorine dioxide based product (“WanBinCell Hair-Growth-Promoting Solution”) that he had developed and that would promote hair regrowth. At the time, I was 100 percent certain that this product was a scam and did not do any significant research on it.

How on earth could something as simple as chlorine dioxide impact hair growth positively? Of course I have read studies and/or papers about totally unexpected things such as intentional scalp injury, follicle plucking, scalp burning from a fire accident, lasers and so on all resulting in new hair growth. However, without at least a few papers from reputable institutions supporting such claims, I was unwilling to even google “chlorine dioxide and hair”. Therefore I decided to largely ignore Mr. Xuewu, although I did respond to his e-mail and later even welcomed him on Twitter.

At some point this year, I got more time to visit the hair loss forums, and I started reading Mr. Xuewu’s threads on some of them and became more curious. Below are the two most active ones:

— His thread on the HLH forums

— His thread on the BTT forums

I got even more interested in what he had to say after I saw his patent filed in early 2012, as well another partly related patent from 1997 (which entailed the use tea tree oil, followed by chlorine dioxide, followed by saw palmetto extract to regrow hair). I was also impressed by all the hard work that Mr. Xuewu was putting into promoting his method. I mean even in a lower middle income level country such as China, Mr. Xuewu could probably have made around $10,000 in the past 6 months if he had decided to use his time on something else rather than promoting his product. I did not spend much time on his somewhat confusing website, but it also seems to be a testament to hard work.

Here is Mr. Xuewu’s Indiegogo Campaign, which I am not planning on supporting. However, if you are fairly wealthy, it is worth donating to Mr. Xuewu in my opinion. I like this guy and his tremendous work ethic. Moreover, considering that he has been working with chlorine dioxide for a few years and even has a patent from early 2012, I do not think that he is suddenly trying to scam people. He could be wrong in his conclusions and his product might end up doing very little when it comes to new hair growth, but I do not get the typical scammer vibe from him.

Readers of this blog should note that I am not keen to immediately try using a new product made in another country where there are possibly no stringent governing bodies such as the FDA in the US.

I could also be very misguided in my decision to even mention this “WanBinCell Hair-Growth-Promoting Solution” from Mr. Xuewu. After all, I was very excited about Dr. Nigam when I started this blog about two years ago, and it seems like I was wrong about all that hoopla (as were 100s of people on the hair loss forums).

However, I always respect hard sincere work. Moreover, we are moving towards an era of biohacking where very intelligent individuals will be able to create groundbreaking products in their kitchen or at DIYbio type community centers. I have firmly believed in this ever since I started reading about Eri Gentry and Biocurious in 2011. If you think about it, most of the numerous companies that are trying to cure hair loss are often severely understaffed and primarily run by one or two key scientists who are the entire brains behind their hair growth technology.

It would not be shocking at all to me if a hair loss cure finally comes from one person’s biohacking attempts, rather than from an established company that keeps raising millions via venture capital funding, but never moves on to final clinical trials.