Regenix and Matthew McConaughey’s Hair Regrowth

Regenix and Matthew McConaughey

— Over the years, there have been numerous rumors on hair loss forums that actor Matthew McConaughey has had hair transplants. However, the actor in the past credited a product called Regenix for his great hair. Mr. McConaughey recently went on the “Live with Kelly” show in the US and credited Regenix yet again with a great review. I have no idea about the ingredients of Regenix since they are proprietary. The manufacturer claims they are all-natural. More on this story here.

— Aclaris Therapeutics’ latest webcast presentation occurred today at the Leerink Partners 6th Annual Global Healthcare Conference. The company’s CEO further elaborated on why they are so optimistic about “highly selective covalently bound JAK 3 inhibitors” helping patients with male pattern hair loss. More importantly, the CEO emphasized on treating female hair loss and how that is even more distressing than male hair loss. You can listen to the whole presentation after registration, and also see the 42 slides in there. For once, someone asked a specific question about covalently bound JAK 3 inhibitors and male pattern hair loss. The most interesting quotes from the CEO:

“Most importantly, androgenic alopecia. Even though that’s traditionally not thought of as an inflammatory process, what they were able to find is that the JAK inhibitors were targeting the stem cell compartment in the hair follicle bulge and actually prolonging and inducing anagen”.

“Being covalently bound…its got a much better shot of not being as promiscous as the other JAK inhibitors”.

— Renowned Singapore based venture capitalist Finian Tan is a major investor in Samumed. I did not realize that he made the decision to invest in the company so suddenly. In his own words: “Only twice in my life I have bet so big on day one”. Poker champion and Samumed CEO Dr. Osman Kibar clearly has some hypnotic powers.

— More developments in finding the genes behind hair loss and baldness. On this blog I have covered several other recent such developments.

— On Hairsite, there is a great question and answer session with Dr. Paul Kemp of HairClone. Dr. Kemp also responded on here a few months ago.

— In the past year, I have posted news about various doctors offering an adipose (fat) cell plus platelet-rich plasma (PRP) combo treatment for hair loss. It seems like this treatment was part of a US based clinical trial. A new article on this subject pointed me towards the main page for the actual website of the trials. They call it STRAAND , which stands for “Stromal Tissue Cell-enriched treatment of Androgenic Alopecia via Novel Deployment”. So far, six doctors are participating. However, unlike in other trials, it seems like patients are responsible for their own expenses.

— A small sample size new study from Italy on non-activated versus activated PRP and the impact of different PRP collection devices on the final result. Dr. Cole from the US is a co-author.

— Replicel CEO Lee Buckler writes his first article for the Huffington Post: “Will 2017 be the year of Cell Therapies?“.

And now on to medical items of interest:

— US patent office hands win in CRISPR battle to Broad Institute and Dr. Feng Zhang.

Human gene editing receives US science panels support. If you have trouble accessing the site, another take here. One day later, a warning from ethicists.

DARPA: We are on the cusp of merging human and machine.

— From the respected “The Economist” magazine: “Printed human body parts could soon be available for transplant“.

— The long quest to create artificial blood may soon be over.

— The tiny robots revolutionizing eye surgery.

Computer lets fully paralyzed patients speak for the first time.

— A lengthy article on Dr. Anthony Atala, with many photos

— First human-pig chimeras created.

Replicel CEO Lee Buckler Addresses us Directly

I have always assumed that Replicel gets far more questions on social media about its hair loss related work versus its tendon repair and skin generation related work. Nevertheless, I do not think that the company’s CEO Lee Buckler ever addressed us hair loss sufferers directly. Until today.

Replicel RCH-01 Release Date

The main point from the video address by Mr. Buckler: the earliest possible release of the company’s RCH-01 hair loss product is in 2018. And that is predicated upon successful clinical trial results from the company’s much larger Japanese partner Shiseido.

I suspect that Mr. Buckler got tired of getting the same question over and over again about when they will release the hair loss product and finally decided to release this latest video. It seems like Replicel’s disagreement with Shiseido from last year is not hurting the two companies’ long-term collaboration.

Replicel and Mr. Buckler have been extremely busy in recent weeks. Just from the past week, you can read and listen to two new interviews from the CEO:

And there was also a detailed favorable report about the company in Zacks Investment Research two weeks ago, along with a “brokered private placement” of common shares.