This Month’s Hair Loss News

Hair loss news first:

— I have covered Samumed and its SM04554 product a few times on this blog in the recent past. The drug is likely not going to be a miracle hair loss cure. I was therefore impressed that the company’s CEO Osman Kibar still managed to recently get profiled on a Forbes magazine cover page. In any case, a few days ago Samumed completed its Phase 2 clinical trials. Now we can only hope that they choose to continue with Phase 3 trials.

— Seems like South Korea’s Dong-A ST updated the Phase 1 clinical trials page for its DA-4001 topical finasteride product.

— Sweden based Follicum’s US patent was approved in July. The patent covers the drug candidate FOL-005.

HairCell, yet another new startup in the hair loss world. This one wants to use a “bioelectric stimulator combined with a micro infusion pump”. Even if the vast majority of these new entrants end up as outright failures or frauds, the frenetic new activity in the hair loss world is great.  HairCell’s phase 1 clinical trials have not yet commenced.

HLT forum member “jgray201” has a very interesting thread that he started in 2012, but updates every so often including several weeks ago.

Joe Tillman has been making some great videos that he then posts on his YouTube channel. When you combine Joe with the highly respected and skilled surgeon Dr. Ron Shapiro, you get an excellent final result.

— Commentator Peter Renardo gives us some more updates on his decades old artery ligation procedure. Extremely interesting, although I would never go through with such a procedure just to save my hair.

— A 2015 presentation on Kerastem by Dr. David Perez-Meza from Spain was posted on an Italian hair loss site last month. Results in 6 patients showed an improvement in all, with an average 14 percent increase in hair count at 6 months. Not that great for the price people pay for this treatment unless the results last for years.

Brief mention of Follica.

— A huge increase in men wanting to become women (MTF transsexuals) in the UK. This will lead to many interesting before and after MTF transition photos of scalp hair regrowth via medication, transplants and castration. The increase in women wanting to become men (FTM transsexuals) is not so useful for our purposes.

El Chapo going bald, although the link between stress and permanent hair loss is tenuous at best in my opinion.

And now on to medical items of interest:

— Stem cell stimulating regenerative dental fillings could eliminate the need for root canals.

Artificial pancreas next year?

— Extremely interesting article on “pausing” people so as to then bring them back from the dead.

Growing human bones from fat cells.

— Finally, we have a biodegradable absorbable stent for heart patients with blocked arteries.

3-parent DNA containing life-forms seem healthy when it comes to monkeys. Note that the UK has already approved this technology for human embryos.

3D printed jaw for cancer survivor.

— Recently, I read an article that referred to an interesting freely available online 3D Human Blastocyst Viewer. You have to click on the bottom left options first and then on all the options on the right side. Way above my head, but there are probably at least three blog commentators on here who will understand this. Also reminds me of Dr. Michael Rendl’s Hair-GEL (gene expression library) site. And Dr. Owen Rakham’s Mogrify,  both of which I have mentioned on this blog in the past.

A transparent skull implant = “window into the brain”. Also make sure to read my post on the first ever full skull and scalp transplant.

Wired magazine’s Kevin Kelly: Next 30 years in technology.

— Thanks to commentator “Susana” from Portugal (who is usually quite pessimistic) for providing us with this link on groundbreaking skin replacement technology from Spain.

Kyocera Branches out from Electronics into Hair Regeneration

Update: RIKEN added a brief summary of this development on its site and included the below photo on its home page:

Kyocera, Tsuji and Organ Partnership

 

Update: Commentator “sets” e-mailed Kyocera and got a response:

“Hello. My name is Hina Morioka from the Corporate Communications Division at Kyocera Corporation. Thank you very much for your question about our research with RIKEN and Organ Technologies.

Regarding timeline, we aim to put the technologies into practical use and make medical treatment available in 2020 in Japan (medical treatment at one’s own expense).”


I was planning on publishing an entirely different post today, but things continue moving along rapidly in the hair loss research world and you regularly encounter sudden usually pleasant surprises.  In the last post, commentator “Lewa” just brought to my attention that major Japanese electronics manufacturer Kyocera was entering the hair regeneration market via a collaboration with the government-affiliated RIKEN Institute in Japan (where the renowned Dr. Takashi Tsuji leads the hair related research department) and Organ Technologies in Japan (a company in which Dr. Tsuji is one of the directors).  In that article, I read that they plan to commence clinical trials BY 2020, but that they also planned to start their business IN 2020.  They will develop prototype equipment by March 2018.  Very ambitious and rapid progression targets, but if it can be done anywhere, it would be in Japan where the government is very supportive of expediting research.  With the addition of Kyocera into the mix, Dr. Tsuji now has access to funding that all other hair researchers around the world can only dream of.  The only other hair loss cure research related company with this kind of funding access is also based in Japan in the name of Shiseido.

At first I was only intending to mention the above development in my once a month “brief items of interest” post.  However, then I discovered an even better version of the above article on Kyocera’s website. This second article is far less ambiguous when it comes to the dates and therefore this development deserves its own post now.  Key quotes from the above second article:

“The companies aim to put the technologies into practical use in 2020.”

“Kyocera, RIKEN and Organ Technologies plan to establish cell culture and transplant technologies and develop devices for transplantation, aiming to put the technologies into practical use for the treatment of human alopecia in 2020 in Japan.”

Update: Forbes magazine now has a story on this news too.
Update: A brief Japan Times summary.

The division of labor between the partner companies will be as follows:

Kyocera = Development of cell processing devices via the utilization of its microfabrication and manufacturing technologies.

RIKEN and Organ Technologies = “Development of stem cell culture/amplification technologies, development of cell manipulation technologies, establishment of production processes, implementation of preclinical studies, etc.”

The technology (“regenerated follicular primordium” via a combination of epithelial stem cells and mesenchymal stem cells) being developed is outlined in the bottom part of the below image taken from Kyocera’s press release.  Top image shows a modern day FUT (strip) hair transplant procedure with limited donor hair supply limitations.

 

Tsuji, RIKEN and Kyocera hair regeneration method