USC — How the Gene Wnt7b Activates Hair Growth

This year has witnessed so much new and interesting hair loss related research, that it is hard to believe that in just this one month three universities published major new findings!

I already covered the news from U Penn (hirsutism) in the US and King’s College (skin cells) in the UK in earlier posts this month. Those two findings were widely covered in the media. However, perhaps I should have covered research from a much lesser known team from University of Southern California in the US first.

USC scientist Krzysztof Kobielak and postdoctoral fellow Eve Kandyba along with other colleagues have published three papers this year related to hair loss.

Wnt7b and Hair Growth

The latest of these three (published in November in the journal Stem Cells, but publicized this month) focuses on how the gene Wnt7b activates hair growth.

Earlier work by this team entailed research on how reduced BMP signaling and increased Wnt signaling activates hair growth, while increased BMP signaling and decreased Wnt signaling keeps hair follicle stem cells (hfSCs) in a resting state. Much more can be read here.

It is also encouraging that this project has received government funding via the National Institute of Arthritis and Musculoskeletal and Skin Diseases.

One thought on “USC — How the Gene Wnt7b Activates Hair Growth”

  1. I just wanted to say thank you and I truly appreciate your blog here. It is an amazing idea, and I really feel that it is something that will change the outcome of when the world gets a hair growth treatment that works for everyone. You focus on the things that uplift us. You show what great work is being done now. You show how close we are. This is wonderful. One sentiment I offer to everyone “haircureNOW”. It could be today when a discovery is made utilizing technology that is already cleared to be used around the world for hair growth. And for today, I will be happy and appreciative anyways.
    God Bless.

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