Mitochondria and Hair

Mitochondria are the powerhouse of every cell in the human body. I am surprised at how little importance hair loss researchers (as well as interested parties such as ourselves) have given to this important subject.

Update: June 2022 — A new study from Singapore finds that there is altered dermal papilla mitochondrial function in androgenetic alopecia. Balding dermal papilla cells were also found to be under significantly higher oxidative stress than non-balding dermal papilla cells.

Note that mitochondria is the plural of the actual organelle known as mitochondrion.

To date, I have only covered this important subject twice on this blog. Moreover, both instances only occurred earlier this year.

New Mitochondrial Hair Treatment Patent

Yesterday, someone on Twitter messaged me about a highly interesting new patent application from Israel. This patent was filed on March 22nd, 2018 and was published on October 4th, 2018.

The scientists involved seem to be highly qualified. All have high levels of education, have started their own companies, and have many patents to their names:

Going back to this particular patent, the scientists make numerous claims in regards to hair loss reversal, new hair growth, hair follicle size and cycle elongation, hair cell proliferation and more. The main method for doing so seems to be via:

“Administering a composition comprising an effective amount of about 1 μg/ml to about 100 μg/ml of intact mitochondria, ruptured mitochondria and/or mitochondrial constituents selected from the group consisting of mitochondrial protein, mitochondrial nucleic acid, mitochondrial lipid and mitochondrial saccharide.”

Writing this post at 11pm, you will have to forgive me for not putting in the effort to try to figure out any further details regarding the above (or the rest of the lengthy patent).

Hopefully, the few scientists among this blog’s commentators will do the hard work for me this time.

Brotzu Lotion Named Trinov. Releasing in Italy Soon.

Update: As expected, Fidia officially announced yesterday that the Brotzu Lotion will be named TRINOV. This much anticipated product will be released in Italy by the end of 2018.

Brotzu Lotion Update

I first covered the highly interesting Brotzu lotion and its octogenarian inventor (Dr. Giovanni Brotzu) in early 2016. Thereafter, I discussed the lotion several more times, including a post from earlier this year regarding the countdown to its release.

I do not want to repeat all the details about this PGE1 precursor (Dihomo-Gamma-Linolenic Acid — DGLA) based product yet again. So please make sure to read all my past posts on the Brotzu lotion.

The Brotzu lotion has caused more frenzy in hair loss forums than any other product during the past year. In the process, it has taken over from the excitement surrounding JAK inhibitors and hair loss.

However, it should be noted that at best, this product will only bring back hair that you have lost in the past several years per Dr. Brotzu. It is definitely not a hair loss cure.

Brotzu Lotion to be Named Trinov

Five days ago, one of the Italian hair loss forum members posted groundbreaking new information about the Brotzu lotion: it will be named Trinov. The forums moderators have nicely summarized this information. Some sources also indicate the names “Tri Nov” as well as “Trinov Capelli”.

The original patent for Trinov was filed by Fidia Farmaceutici (Italy) on June 11th 2018. It looks like a patent for rights to both the name “Trinov”, and the appearance of the Trinov logo. Another related patent was filed on July 30th 2018.

Also significant, it seems like Fidia Farmaceutica has registered a new domain called Trinov Anticaduta.

You can track the latest developments regarding the Brotzu lotion in the below forums:

Trinov Product Release in October?

From some of the above threads, it seems like the Trinov product will be released in October 2018. However, I would not count on this to be a certainty, as we have learnt many a times in the past.

Keep checking out Fidia’s news section for future updates on Trinov.