Part 1 Here
Me: If you hire a western scientist to work at your lab (even if its a non hair loss related biologist), it will boost your credibility drastically…that is if you care about credibility on forums etc…
Dr. Nigam: Yes, Dr. Gerd (Lauster) will be the first.
For the time being..I am not for marketing or credibility..I want real success in this field..and it would speak for itself…I would rather focus on meeting, communicating with relevant people..who can help me solve the probs I am facing as I move forward with newer experiments..Ask Mwamba..I have already solved the problem of scarless fue..first in the world..which is a small achievement but nevertheless..an achievement ..to contribute in the hair restoration industry
Me: Wow that is a big achievement if you can present it at a conference.
Dr. Nigam: Yes I will present in a conference. Lot of potential associations we spoke ..and will finalize shortly critics cannot believe even this…but Mwamba was so excited about this ..that he will be offering at his clinic shortly.. I can take any scrutiny to prove..that we have solved the problem of white dots or scars in hair restoration…at least let me prove this…and than may be people can go to the next level to scrutinize and think about the denovo doubling and partial success with pure hm injections. Donor regen…we are moving faster..as it is non aga scalp…by injecting dp cultures, hair stemcells and growth factors
Me: What did you discuss with Dr. Jahoda at the recent ISHRS Conference? Any other interesting interactions from the conference?
Dr. Nigam:
Discussed with Jahoda..
1)How is he thinking to improve the trichogenicity of 3d spheroidal dp cultures. Shared what I am doing to achieve the same.
2)Also discussed how we are planning to produce mass scale 3d spheroidal dp’s with pva coated low adherent tubes.
Also discussed the problem I am facing in transferring 3d spheroids from the petri dish in the lab to the patients scalp..as any movement dissociates the cells.
What would be the ideal number of cells per 3d spheroid of dp.
In his presentation he spoke about the master regulation gene which christiano is trying to locate, upregulation of the same should be sufficient to enhance the trichogenicity of the cultured dp cells.
He also mentioned in his presentation that… as on today hair doubling is possibility..as upper part of amputated follicle with intact dermal cup sheath can create it’s own dermal papilla…as the demal cup sheath cells are progenitor or mother cells to the dermal papilla cells.
That is what I have been talking about and doing…with further addition of fresh trichogenic dp cells and growth factors into the upper bisected follicle.
Also Met Dr Washenik, discussed their research work and findings at Aderans, showed my work ,spent a good time with Dr. Cole and Dr. Mwamba.
Met a whole lot of surgeons…few called me the rebellious doctor..!
I was approached by seven surgeons from Canada,USA,UK,who were quite interested to be a part of our research activity and offer their support, for furthering our work and how they could incorporate the same,at their clinic.
Interesting among them was this team, who were working with induced pluripotent stemcells from Las Vegas.
I will be present in major stemcell conferences and would visit stemcell research laboratories in Japan, China,Germany and UK in next six months.
Not only stemcell hair conferences and lab but also other than hair, stemcell conferences and labs.
Due to better funding,people researching in other diseases with stemcell ,are moving faster ,specially in the field of 3d culture and enhancement of trichogenicity of stemcells.
I believe,the next advancement for mpb cure would be,
1) Tissue engineering with stemcell and growth factors to enhance donor regeneration and better survival of the implanted grafts…with the fusion of hair restoration with the tissue engineering.
2) Next stage would be activation of dormant follicles with tissue eng.
3) And ultimately creation of neofollilces which are dht resistant, with autologas autologous stemcell and or induced pluripotent stemcelsl.
If aderans, replicelll, dr nigam have produced at least, in few patients scalp, sufficiently good amount of Terminal hair with hm injections alone…,and why should every or most of the scalps… not respond the same way
The time is not too far before the success percentage improves with pure hm injections .
Had the regulations been more relax, for at least autologas hair stemcell ,scientists would have been closer to cure by now.
My applied research work is dedicated to these scientists.
Not an individual… but the group of experts likes cell biologists,Immunologists,genetic experts,allied biotech experts,nano technologists ,hair transplant surgeons etc. with high tech laboratories, with clinical trials..at the right location with relax regulations.. is the only way to reach cure faster…. this is what I want to do …. and getting investment for such a team effort.. will not be difficult.
Will be at Berlin next month to meet Gerd….trying whatever I can…