Dr. Michael Rendl — Mesenchymal Control of Hair Follicle Formulation, Growth and Regeneration

On this blog, I have in the past discussed various dermatological associations and non-profits, including several important ones in the United States such as the American Academy of Dermatology (AAD) and Advancing Innovation in Dermatology (AID).  A third one called the Society for Investigative Dermatology (SID) recently had its 75th annual meeting on May 11th, 2016.

On SID’s youtube channel, you can find a number of the video presentations from this meeting, including a few that discuss hair in at least part of the presentation.  On SID’s website they have a summary list of presentations that includes quite a few involving hair, but none of those videos seem to be available as yet.  Hopefully they will make more of them publicly available soon assuming they videotaped all the presentations.

For now, the most relevant video when it comes to our cause is a presentation by Dr. Michael Rendl that I have embedded below.  On this blog, I have discussed Dr. Rendl’s work several times in the past, including in this post about his Rendl lab.  The below video is highly interesting, especially when it comes to the crucial dermal papilla cell and its induction of hair growth.  I did not realize how complicated this process is and how researchers still have so many uncertainties about the various signals, transcription factors, pathways and processes that lead to the dermal papilla inducing hair growth.

The parts on gene expression, RNA deep-sequencing and CRISPR-mediated genome editing are also very interesting, especially since CRISPR has been in the news so much in the past year (and it now seems inevitable that adult humans will be able to have their genes edited in the future).  A lot of the content is very technical and way above my head.

Kudos to Dr. Rendl for creating the hair-GEL (gene expression library) website for sharing this crucial information with everyone for free.

It is too bad that Dr. Rendl is totally bald and seems to be very comfortable with that look.  I would have preferred it if he had a combover or hairpiece that would suggest much more of a personal interest in this subject matter (as we have seen with Dr. Angela Christiano, who wears a wig fit for a queen).


11 thoughts on “Dr. Michael Rendl — Mesenchymal Control of Hair Follicle Formulation, Growth and Regeneration”

  1. Don’t worry admin, lots of people who shave their heads willingly still want their hair back. Thanks for the info you da real mvp

  2. Dear All,
    apart from all these wonderful new things, I reaaly like to check if there are advances known on old interesting findings.
    in the study of 2009 , I saw very interesting data ( and pictures!) for a combination of natural substances to promote hair growth.


    Do anyone knows more on this ? any feedback would be apprecciated since this taking some soia milk and some more pepper powder is something easy to start up and add in a safe way to my anti hair-loss regimen ( only minoxidil and caffeine based shampoo). Thanks in any case!

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