Dermarolling, Minoxidil, PGD2 and PGE2

As if one unprecedented phenomenon (see my prior post) was not enough, 2013 also witnessed the emergence of a second more scientifically grounded phenomenon in dermarolling in combination with the application of Minoxidil (Rogaine). Creative and intelligent hair loss forum members are also experimenting with the addition of PGD2 (prostaglandin D2) inhibitors and PGE2 (prostaglandin E2) to this mix.

The logic behind these experiments is related to the wounding and resulting hair regrowth that a company called Follica is attempting, and a recent study on the enhanced positive effect of Minoxidil in combination with dermarolling/microneedling with a dermaroller imply a strong proven scientific basis for the excitement surrounding this issue.  I myself have seen decent results from applying Minoxidil to my scalp for a number of years, and will perhaps try dermarolling in the future.

I will elaborate on this subject in more detail in future posts, but for now I encourage readers to go through the following massive threads on the main hair loss forums in order to gauge the excitement around this issue:

The baldtruthtalk forum thread on dermarolling and minoxidil

The hairlosstalk forum thread on dermarolling and minoxidil

The hairlosshelp forum thread on dermarolling and minoxidil

9 thoughts on “Dermarolling, Minoxidil, PGD2 and PGE2”

  1. Hii i have a question about derma rolling efficiency.
    Can the healing process be depleted or in any way, be exhausted if used for long as if now im 18 and i start rolling today, so is their any chance that the whole reservoir of healing be empty due to regular use??

  2. I have decided after doing a week of research that I’m giving derma rolling a go. I started last friday.

    I don’t have access to the research drugs other people are using in some online records. Nor do I want to use drugs that haven’t yet passed through known saftey efficacy tests.

    So my regime will continue as follows.

    Topical finasteride and minoxidil, twice a day.

    Stemoxidine, around 3 ml, once or twice a day. I know the jury is out on stemoxidine, but it’s cheap and available and lots of people have used it for a long time with mixed reviews. I’ll give it a whirl.

    Nitzoral 2% twice a week

    Alpecin shampoo e/d.

    Maybe I’ll chuck in some rosemary oil before bed time. Any advice on something to go with the rosemary would be good. Might search for some pumpkin seed oils and some seaweed extracts.

    Finally. I’ll dermaroll with a 1.5 192 needles roller, once a week.

    I’m considering logging my progress somewhere with photos. If anyone is interested then let me know.

  3. So if I basically create a thread on any particular hair loss forum, I can link it here?

    I’ve just taken some base line pics. Albeit 2.5 months on fin and minox topically. I’ve noticed a general, slight thickening all over and have had lots of miniature hair growth. So I thought I best take it now.

    Not that I want to muddy the waters as im sure I am going to respond pretty well to the fin and minox. But I’ve been down this road before, a few years back, taking fin and min. So I know what to expect. I’m hoping that the dermarolling will show better results. Gradually I will steer more towards the protocol of swiss temples. Bar the fact I will continue with the topical fin and min. O have way more research to do before I head down that path. So for at least 3 months I am just sticking with the fin, min, Nitzoral, stemox and derma rolling.
    Maybe add in some rosemary and castor oil.

    So for people familiar with swiss temples regime, you’ll see I’m only a couple of compounds off the full protocol.

    I’m in for the long haul on this one. I have nothing to lose!

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