Category Archives: Rodney Sinclair

Link between hair cells and fat cells could lead to fat dissolving cream?!

Hair loss researchers have in recent years published a few studies related to the link between fat cells and hair cells. In the latest findings, a new research paper by Dr. Fiona Watt, Dr. Rodney Sinclair and others concluded that “epidermal Wnt/β-catenin is a critical initiator of a signaling cascade that induces adipogenesis and highlights the role of epidermal Wnt signaling in synchronizing adipocyte differentiation with the hair growth cycle”.

Apparantly, the implications of this work are that a fat dissolving cream could soon be invented.

Of course most of us are interested in the hair loss aspect of this research and not too concerned about the fat cells link. However, excessive fat/obesity is now becoming as common as baldness in men, and is in fact far more common than baldness in women. Many obese people do not eat too much and are not lazy as often depicted in the media. Rather, their genetics and hormonal makeup often makes it close to impossible for them to loose and keep too much weight off.  Even with their best effort to exercise and limit caloric intake daily, some people will always be 50 pounds overweight.

It is therefore not surprising that the same pathways examined in prior hair loss related research are now being examined in order to potentially develop a blockbuster fat dissolving cream. Unfortunately, even if developed, such a cream would not aid in reducing the more dangerous excessive visceral fat around our essential organs. The fat that would be reduced is the less dangerous subcutaneous fat, which is cosmetically distressing for a lot of people.