Category Archives: Finasteride

News from Japan — Finasteride More Effective on Japanese Men and a Shiseido Update

Finasteride more effective on Japanese men than on Caucasian men

A very important study titled “Five-year efficacy of finasteride in 801 Japanese men with androgenetic alopecia” was just published in the Journal of Dermatology (it was received in 2014, but released now).  Unfortunately, Google Scholar does not have a free version of the study, although I was able to preview the first page here.

Apparently, this was the first major long-term (≥ 5 years) study on oral Finasteride use to treat  hair loss in Japanese men.  A major 3-year efficacy study was published in the past that showed improvement in 78 percent of Japanese patients.  However, this new five-year study showed improvement in a stunning 99.4 percent of the 810 patients who took 1mg finasteride per day for 5 years or more!

The authors (led by Dr. Akio Sato) conclude that Japanese hair loss sufferers are probably much better responders to Finasteride than are Caucasian men.  They cite a prior large-scale 1,553 person study on Caucasian men that showed a 48 percent improvement after 5 years (I am guessing that most of the remainder saw maintenance).

The authors mention that on average, Japanese men bald 10 years later than Caucasian men — and from my own observations, Japanese men also bald far less frequently than Caucasian men. This latest study on Japanese men also showed better responses in those that had less pre-existing baldness and started treatment at a younger age.  As is almost always the case with these studies, the side effects from long-term Finasteride use were minimal.

On hair loss forums, you will often read anecdotal reports about persistent relatively serious side effects in some people who have taken Finasteride for a while, and it is up to you and your doctor to decide on whether its worth this risk.  I take 1.25mg Finasteride every two days and may raise my dose to 1mg daily in the future.

Shiseido update from Japan

Also from Japan, Shiseido was covered in a local paper that you need to translate into English.  A take on that article from a two-person Canadian-Japanese translation team named “Master Blaster” can be read here.  It seems like Replicel thinks that the cure will be here in 2018, although I will only buy that time-frame once their final clinical trial results come through later this year and show limited side effects as well as positive hair growth results.  I am nevertheless very pleased to read about an even more optimistic timeline for a cure than I project on this blog’s name.

Before and After Finasteride and Minoxidil Photos

While we await a true cure, for those who have not lost too much of their hair yet, taking the combination of Finasteride and Minoxidil can often result in excellent results.  For those who have already lost a lot of hair, with rare exceptions, modest regrowth and maintenance are unfortunately the best you can hope for with these medications.

My recent post on collecting Dutasteride testimonials made me realize that I should write this post for people who are highly skeptical of Finasteride.  Dutasteride, if approved to treat hair loss, will certainly be superior to Finasteride (albeit with higher rates of side effects).

On this page, I will post links to before and after photos on various hair transplant surgeon’s websites of patients who have had good to great results from Finasteride and/or Minoxidil treatment.  Most patients take both medications.

Before and after hair loss medication photos from Dr. Rogers’ website

Before and after hair loss medication photos from Dr. Bernstein’s website

Before and after Finasteride photos from Dr. Collins’ website.  And one more with just the crown.

Before and after hair loss medication photos from Dr. Lam’s website

Belgravia Centre UK Success Stories (it seems like some of their patients get high-dose Minoxidil 12.5%)