A Good Recent Alopecia Areata Video from Dr. Angela Christiano

Despite the main focus of this blog being on androgenic alopecia (also known as male pattern baldness, even though females suffer from it too), I have made a number of posts about alopecia areata on here in the past year.  This is largely due to all the good news that has come out this year for people suffering from alopecia areata from the great work of people such as Dr. Angela Christiano and Dr. Brett King. In my opinion, there is also a chance that these drugs may benefit people with certain types of angrogenic alopecia where there is an inflammatory (dandruff, itching, scaling) component involved too, but this is pure conjecture on my part and entirely unproven.

Dr. Christiano recently published a good video (with more of a female focus, a rarity in the hair loss research world) on alopecia areata that includes her personal experiences with the disease.  The video is embedded below.  She has a few interesting slides on there:

  • 11:00 = I was quite surprised to read that alopecia areata affects 5.3 million people in the US, with a 1.7 percent lifetime risk.
  • 11:42 = comparison with genes involved in psoriosis and vitiligo.
  • 12:15 and 12:45 = most important part of the presentation related to research on Janus kinase (JAK) inhibitors such as Ruxolitinib (JAK 1,2), Tofacitinib (JAK 1,2,3), Baricitinib (JAK 1,2), VX-509 (JAK 1,2) and R348 (JAK 1,2).  The last three mentioned are not yet approved, while the first two are FDA approved for certain applications and you can read about those drugs via the “Categories” section in the left hand column of this blog.
  • 12:57 = Results on mice.
  • 23:47 = Great results on a woman and, thereafter, on a man.

4 thoughts on “A Good Recent Alopecia Areata Video from Dr. Angela Christiano”

  1. Hola estos medicamentos pueden llegar a servir para la alopecia androgenetica??? hay novedades si en el 2015 pueden llegar a salir nuevas alternativas???? alguien sabe algo?

  2. I am female and have had AA since I was 15 (I am 35 now). Its been my experience that doctors never gave AA the credibility it deserved because it doesn’t cause physical pain. Over the years I’ve taken my theories to doctors only to go down the same two dead ends of the system- they were only willing to test my thyroid or send me to the dermatologist. Once I did get an allergy doctor, who had previously had a career doing research for Yale, justify a food allergy test. And I’m not alone, there are many blogs, articles, books etc of people fighting, and surviving on hope just like I was.

    Little did we know that among our ranks was Dr. Christano and her amazing team and partners! God bless the day her hair stylist discovered her AA! For the depth of my pain that AA has caused will be the height of my joy and gratitude for a head of hair!

    Thank you Dr. Christano for letting your pain turn to passion and for your articulation in this presentation of what its like emotionally to have AA. My daughter and I love your hair and admire you for who you are as a woman. Blessings be with you. (I know this is all in the trial stage but I cant help it! Hooray!! Finally!)

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